ES251166A1 - Un procedimiento de preparacion de derivados hidrosolubles de una hormona esteroide - Google Patents
Un procedimiento de preparacion de derivados hidrosolubles de una hormona esteroideInfo
- Publication number
- ES251166A1 ES251166A1 ES0251166A ES251166A ES251166A1 ES 251166 A1 ES251166 A1 ES 251166A1 ES 0251166 A ES0251166 A ES 0251166A ES 251166 A ES251166 A ES 251166A ES 251166 A1 ES251166 A1 ES 251166A1
- Authority
- ES
- Spain
- Prior art keywords
- salt
- testosterone
- alkali metal
- preparation
- disulphamylbenzoate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 3
- -1 steroid compounds Chemical class 0.000 title abstract 2
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 abstract 8
- 150000003839 salts Chemical class 0.000 abstract 5
- 229910052783 alkali metal Inorganic materials 0.000 abstract 4
- 229960003604 testosterone Drugs 0.000 abstract 4
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 150000001340 alkali metals Chemical class 0.000 abstract 3
- VYWYYJYRVSBHJQ-UHFFFAOYSA-M 3,5-dinitrobenzoate Chemical compound [O-]C(=O)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1 VYWYYJYRVSBHJQ-UHFFFAOYSA-M 0.000 abstract 2
- LRLKURLTXFBDNQ-UHFFFAOYSA-N 3,5-disulfamoylbenzoic acid Chemical compound NS(=O)(=O)C1=CC(=CC(=C1)C(O)=O)S(N)(=O)=O LRLKURLTXFBDNQ-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- 159000000000 sodium salts Chemical class 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- VYWYYJYRVSBHJQ-UHFFFAOYSA-N 3,5-dinitrobenzoic acid Chemical class OC(=O)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1 VYWYYJYRVSBHJQ-UHFFFAOYSA-N 0.000 abstract 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical compound [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical group OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR771805A FR1238739A (fr) | 1958-08-04 | 1958-08-04 | Procédé de préparation de dérivés hydrosolubles de testostérone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES251166A1 true ES251166A1 (es) | 1959-11-01 |
Family
ID=8707176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0251166A Expired ES251166A1 (es) | 1958-08-04 | 1959-07-30 | Un procedimiento de preparacion de derivados hidrosolubles de una hormona esteroide |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE581323A (fr) |
| CH (1) | CH378876A (fr) |
| ES (1) | ES251166A1 (fr) |
| FR (1) | FR1238739A (fr) |
| GB (1) | GB915129A (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004025985A1 (de) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estriol- und Estetrol-Prodrugs |
| DE102004025966A1 (de) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estradiol-Prodrugs |
-
1958
- 1958-08-04 FR FR771805A patent/FR1238739A/fr not_active Expired
-
1959
- 1959-07-07 CH CH7544259A patent/CH378876A/fr unknown
- 1959-07-16 GB GB2449259A patent/GB915129A/en not_active Expired
- 1959-07-30 ES ES0251166A patent/ES251166A1/es not_active Expired
- 1959-08-03 BE BE581323A patent/BE581323A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB915129A (en) | 1963-01-09 |
| BE581323A (fr) | 1960-02-03 |
| FR1238739A (fr) | 1960-08-19 |
| CH378876A (fr) | 1964-06-30 |
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