ES2531018T3 - Vacuna contra la tuberculosis y método de uso de la misma - Google Patents

Vacuna contra la tuberculosis y método de uso de la misma Download PDF

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Publication number
ES2531018T3
ES2531018T3 ES08745627T ES08745627T ES2531018T3 ES 2531018 T3 ES2531018 T3 ES 2531018T3 ES 08745627 T ES08745627 T ES 08745627T ES 08745627 T ES08745627 T ES 08745627T ES 2531018 T3 ES2531018 T3 ES 2531018T3
Authority
ES
Spain
Prior art keywords
tuberculosis vaccine
composition
inactivated
host
mucosal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08745627T
Other languages
English (en)
Inventor
Jennifer Lighter
Jason Fisher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mico Bio Inc
Original Assignee
Mico Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mico Bio Inc filed Critical Mico Bio Inc
Application granted granted Critical
Publication of ES2531018T3 publication Critical patent/ES2531018T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Una composición farmacéutica que comprende Mycobacterium tuberculosis (M. tb) inactivada completa, en la que dicha composición está formulada para una administración intranasal, mucosal o intrapulmonar a un hospedador mamífero, y en la que dicha composición comprende una dosis inmunológicamente protectora cuando es administrada a dicho hospedador, y en la que dicha M. tb está inactivada con irradiación.
ES08745627T 2007-04-12 2008-04-11 Vacuna contra la tuberculosis y método de uso de la misma Active ES2531018T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92330107P 2007-04-12 2007-04-12
PCT/US2008/060065 WO2008128065A2 (en) 2007-04-12 2008-04-11 Tuberculosis vaccine and method of using same

Publications (1)

Publication Number Publication Date
ES2531018T3 true ES2531018T3 (es) 2015-03-09

Family

ID=39523390

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08745627T Active ES2531018T3 (es) 2007-04-12 2008-04-11 Vacuna contra la tuberculosis y método de uso de la misma

Country Status (14)

Country Link
US (3) US8394389B2 (es)
EP (1) EP2144626B8 (es)
JP (2) JP5713672B2 (es)
AU (1) AU2008240181B2 (es)
CA (1) CA2682870C (es)
CY (1) CY1117290T1 (es)
DK (1) DK2144626T3 (es)
ES (1) ES2531018T3 (es)
HR (1) HRP20150177T1 (es)
HU (1) HUE024427T2 (es)
PL (1) PL2144626T3 (es)
PT (1) PT2144626E (es)
SI (1) SI2144626T1 (es)
WO (1) WO2008128065A2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008240181B2 (en) 2007-04-12 2014-01-09 Jason Fisher Tuberculosis vaccine and method of using same
WO2012137072A1 (en) 2011-04-06 2012-10-11 Biovaxim Limited Therapeutic vaccine compositions inducing tolerance to hiv for treating hiv infections in humans
US9839684B2 (en) 2011-04-06 2017-12-12 Biovaxim Limited Pharmaceutical compositions comprising inactivated HIV viral particles and non-pathogenic lactobacilli for the induction of antigen-specific immunotolerance
CA2833633A1 (en) * 2011-04-20 2012-10-26 Jason Fisher Composition and method for enhancing an immune response
ES2438690B1 (es) * 2012-06-15 2015-01-16 Fundació Institut Per A La Investigació En Ciències De La Salut "Germans Trias I Pujol" (Igtp) Unitat De Tuberculosi Experimental Micobacterias inactivadas para su uso por vía oral en la prevención de la tuberculosis
WO2014001571A1 (en) * 2012-06-29 2014-01-03 Lysando Ag Composition for use in mycobacteria diagnosis
EP2679677A1 (en) * 2012-06-29 2014-01-01 Lysando Aktiengesellschaft Composition for use in Mycobacteria therapy
EP2679232A1 (en) * 2012-06-29 2014-01-01 Lysando Aktiengesellschaft Composition for use in Mycobacteria vaccination
KR101615186B1 (ko) 2014-03-07 2016-04-25 연세대학교 산학협력단 결핵 백신의 면역효과 증강용 조성물 및 면역효과 증진 방법
KR101631054B1 (ko) * 2015-12-31 2016-06-16 중앙대학교 산학협력단 마이코박테리아 유래 CFP-10 또는 Ag85B에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편
US10279031B2 (en) * 2016-05-11 2019-05-07 Phibro Animal Health Corporation Composition comprising antigens and a mucosal adjuvant and a method for using
WO2018006939A1 (en) 2016-07-05 2018-01-11 Universidad De Zaragoza Inactivated tuberculosis vaccine
CN108743931B (zh) * 2018-05-02 2022-08-16 成都威斯克生物医药有限公司 抗结核病疫苗及其制备方法和用途
WO2020115161A1 (en) 2018-12-04 2020-06-11 Sabiotec Spin-Off Sl Immunostimulant for use against pathogens

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8404280D0 (en) * 1984-02-17 1984-03-21 Stanford J L Biological preparations
US4724114A (en) 1984-04-23 1988-02-09 Kimberly-Clark Corporation Selective layering of superabsorbents in meltblown substrates
SE9900495D0 (sv) * 1999-02-12 1999-02-12 Pharmatrix Ab Vaccine composition
DE60226175T2 (de) * 2001-11-14 2009-07-09 Novavax, Inc. Mycobakterieller impfstoff
KR20050008453A (ko) 2002-03-08 2005-01-21 바쿠레시 마파탈 카마르 결핵 관리에 유용한 약제학적 조성물의 제조방법
BRPI0612833A2 (pt) * 2005-06-23 2010-11-30 Statens Seruminstitut composição imunogênica, vacina, composição farmacêutica, polipeptìdeo de fusão e uso das três primeiras
AU2008240181B2 (en) 2007-04-12 2014-01-09 Jason Fisher Tuberculosis vaccine and method of using same

Also Published As

Publication number Publication date
US20100112007A1 (en) 2010-05-06
US20150258187A1 (en) 2015-09-17
EP2144626B8 (en) 2015-02-18
US8932608B2 (en) 2015-01-13
JP2010523711A (ja) 2010-07-15
JP2015038130A (ja) 2015-02-26
WO2008128065A3 (en) 2008-12-18
CA2682870C (en) 2016-08-09
WO2008128065A2 (en) 2008-10-23
AU2008240181B2 (en) 2014-01-09
PT2144626E (pt) 2015-03-03
EP2144626B1 (en) 2014-12-03
EP2144626A2 (en) 2010-01-20
DK2144626T3 (en) 2015-02-09
PL2144626T3 (pl) 2015-09-30
US8394389B2 (en) 2013-03-12
JP5713672B2 (ja) 2015-05-07
US9636391B2 (en) 2017-05-02
CA2682870A1 (en) 2008-10-23
HUE024427T2 (en) 2016-01-28
SI2144626T1 (sl) 2015-04-30
AU2008240181A1 (en) 2008-10-23
US20130273110A1 (en) 2013-10-17
HRP20150177T1 (hr) 2015-04-10
CY1117290T1 (el) 2017-04-26

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