ES2531254T3 - Monitor de brote-supresión para coma inducido - Google Patents

Monitor de brote-supresión para coma inducido Download PDF

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Publication number
ES2531254T3
ES2531254T3 ES07875122T ES07875122T ES2531254T3 ES 2531254 T3 ES2531254 T3 ES 2531254T3 ES 07875122 T ES07875122 T ES 07875122T ES 07875122 T ES07875122 T ES 07875122T ES 2531254 T3 ES2531254 T3 ES 2531254T3
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ES
Spain
Prior art keywords
outbreak
suppression
processor
absolute amplitude
user
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07875122T
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English (en)
Inventor
Michael J Bier
David A Kaiser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California San Diego UCSD
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University of California Berkeley
University of California San Diego UCSD
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Publication of ES2531254T3 publication Critical patent/ES2531254T3/es
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4821—Determining level or depth of anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A61B5/372—Analysis of electroencephalograms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Artificial Intelligence (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Signal Processing (AREA)
  • Fuzzy Systems (AREA)
  • Mathematical Physics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Evolutionary Computation (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Debugging And Monitoring (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

Un método para monitorizar un sujeto sedado usando un procesador lógico, que comprende: recibir datos digitales que representan el electroencefalograma, EEG, de dicho sujeto en dicho procesador; calcular una diferencia de amplitud absoluta (di) a través de la señal de EEG, con un historial de 1 segundo, alisando de este modo para minimizar los efectos de la variación de la señal sobre la detección del inicio; usar dicho procesador para determinar uno o más inicios de brote detectando un inicio de brote cuando una diferencia de amplitud absoluta alisada supera un criterio basado en la mediana de la amplitud absoluta del EEG multiplicada por un factor especificado; usar dicho procesador para determinar uno o más inicios de supresión detectando un inicio de supresión cuando la diferencia de amplitud absoluta alisada va por debajo de la mediana de la amplitud absoluta; usar dicho procesador para determinar uno o más intervalos de brote-supresión, determinando el tiempo entre un inicio de la supresión y un inicio del brote posterior, independientemente de la duración del brote; usar dicho procesador para determinar un intervalo de brote-supresión medio en curso para una duración temporal especificada junto con un nivel de confianza estadística; y presentar dados que indican dicho intervalo de brote-supresión medio en curso a un usuario, proporcionando de este modo a dicho usuario información para guiar el ajuste de terapia para el mantenimiento de un estado de sedación deseado, en el que dicha presentación comprende presentar datos al usuario que indican el intervalo de brote-supresión medio en curso y que también indican el nivel de confianza del intervalo de brote-supresión medio en curso.
ES07875122T 2006-09-29 2007-10-01 Monitor de brote-supresión para coma inducido Active ES2531254T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82743306P 2006-09-29 2006-09-29
PCT/IB2007/004703 WO2009004403A2 (en) 2006-09-29 2007-10-01 Burst suppression monitor for induced coma

Publications (1)

Publication Number Publication Date
ES2531254T3 true ES2531254T3 (es) 2015-03-12

Family

ID=39827585

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07875122T Active ES2531254T3 (es) 2006-09-29 2007-10-01 Monitor de brote-supresión para coma inducido

Country Status (5)

Country Link
US (2) US8649855B2 (es)
EP (1) EP2076173B1 (es)
DK (1) DK2076173T3 (es)
ES (1) ES2531254T3 (es)
WO (1) WO2009004403A2 (es)

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US8914115B2 (en) * 2009-12-03 2014-12-16 Medtronic, Inc. Selecting therapy cycle parameters based on monitored brain signal
US20130310422A1 (en) 2010-09-01 2013-11-21 The General Hospital Corporation Reversal of general anesthesia by administration of methylphenidate, amphetamine, modafinil, amantadine, and/or caffeine
US8565886B2 (en) 2010-11-10 2013-10-22 Medtronic, Inc. Arousal state modulation with electrical stimulation
US8706181B2 (en) 2011-01-25 2014-04-22 Medtronic, Inc. Target therapy delivery site selection
US11559237B1 (en) * 2011-08-24 2023-01-24 Neurowave Systems Inc. Robust real-time EEG suppression detection device and method
US20130072809A1 (en) * 2011-09-19 2013-03-21 Persyst Development Corporation Method And System For Analyzing An EEG Recording
US20140194769A1 (en) * 2011-09-19 2014-07-10 Persyst Development Corporation Multiple Patient EEG Monitoring
WO2014059418A1 (en) 2012-10-12 2014-04-17 The General Hospital Corporation System and method for monitoring and controlling a state of a patient during and after administration of anesthetic compound
EP2988658A1 (en) * 2013-04-23 2016-03-02 The General Hospital Corporation Monitoring brain metabolism and activity using electroencephalogram and optical imaging
JP6660878B2 (ja) 2013-06-27 2020-03-11 ザ ジェネラル ホスピタル コーポレイション 生理学的データにおける動的構造を追跡するためのシステムおよび該システムの作動方法
US10383574B2 (en) * 2013-06-28 2019-08-20 The General Hospital Corporation Systems and methods to infer brain state during burst suppression
US10602978B2 (en) 2013-09-13 2020-03-31 The General Hospital Corporation Systems and methods for improved brain monitoring during general anesthesia and sedation
CN105193409B (zh) * 2015-08-07 2018-01-16 深圳大学 一种脑电抑制水平评估方法及系统
US10786168B2 (en) 2016-11-29 2020-09-29 The General Hospital Corporation Systems and methods for analyzing electrophysiological data from patients undergoing medical treatments
US10953192B2 (en) 2017-05-18 2021-03-23 Advanced Brain Monitoring, Inc. Systems and methods for detecting and managing physiological patterns
CN109009089B (zh) * 2018-05-08 2021-06-15 南京伟思医疗科技股份有限公司 一种适用于新生儿的脑电信号爆发抑制检测方法
CN109259764B (zh) * 2018-07-27 2021-05-14 昆明理工大学 一种确定动态脑功能网络阈值方法
SG11202108509VA (en) * 2019-02-08 2021-09-29 Univ Nanyang Tech Method and system for seizure detection

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US4846190A (en) 1983-08-23 1989-07-11 John Erwin R Electroencephalographic system data display
ATE77038T1 (de) 1985-07-30 1992-06-15 Swinburne Ltd Elektroenzephalograph zur ueberwachung des bewusstseinszustandes und der narkosetiefe.
SE8600289L (sv) 1986-01-23 1987-07-24 Icor Ab Anordning for bestemning av narkosdjup
US5010891A (en) 1987-10-09 1991-04-30 Biometrak Corporation Cerebral biopotential analysis system and method
US5195531A (en) 1991-03-01 1993-03-23 Bennett Henry L Anesthesia adequacy monitor and method
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Also Published As

Publication number Publication date
EP2076173B1 (en) 2014-12-17
US8649855B2 (en) 2014-02-11
US20140249444A1 (en) 2014-09-04
EP2076173A2 (en) 2009-07-08
US20080249431A1 (en) 2008-10-09
US9597006B2 (en) 2017-03-21
WO2009004403A2 (en) 2009-01-08
WO2009004403A3 (en) 2009-08-27
EP2076173A4 (en) 2012-06-06
DK2076173T3 (da) 2015-02-09

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