ES254059A1 - Un procedimiento para preparar un derivado esteroide de la serie del pregnano - Google Patents
Un procedimiento para preparar un derivado esteroide de la serie del pregnanoInfo
- Publication number
- ES254059A1 ES254059A1 ES0254059A ES254059A ES254059A1 ES 254059 A1 ES254059 A1 ES 254059A1 ES 0254059 A ES0254059 A ES 0254059A ES 254059 A ES254059 A ES 254059A ES 254059 A1 ES254059 A1 ES 254059A1
- Authority
- ES
- Spain
- Prior art keywords
- steroid
- radicals
- treating
- streptomyces
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003431 steroids Chemical class 0.000 title abstract 5
- -1 alkyl radicals Chemical class 0.000 abstract 8
- 241000187747 Streptomyces Species 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000004593 Epoxy Substances 0.000 abstract 1
- 241000187654 Nocardia Species 0.000 abstract 1
- 229910018162 SeO2 Inorganic materials 0.000 abstract 1
- 241000958254 Streptomyces argenteolus Species 0.000 abstract 1
- 241000813867 Streptomyces roseochromogenus Species 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- JPJALAQPGMAKDF-UHFFFAOYSA-N selenium dioxide Chemical compound O=[Se]=O JPJALAQPGMAKDF-UHFFFAOYSA-N 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77859558A | 1958-12-08 | 1958-12-08 | |
| US82563959A | 1959-07-08 | 1959-07-08 | |
| US83585659A | 1959-08-25 | 1959-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES254059A1 true ES254059A1 (es) | 1960-05-01 |
Family
ID=27419743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0254059A Expired ES254059A1 (es) | 1958-12-08 | 1959-12-09 | Un procedimiento para preparar un derivado esteroide de la serie del pregnano |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE585432A (es) |
| ES (1) | ES254059A1 (es) |
| GB (2) | GB933868A (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX3864E (es) * | 1975-05-27 | 1981-08-26 | Syntex Corp | Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona |
| WO1994025478A1 (en) * | 1993-04-29 | 1994-11-10 | Instytut Farmaceutyczny | 16α,17α-ACETAL GLUCOCORTICOSTEROIDAL DERIVATIVES |
| WO2005028495A1 (en) * | 2003-09-24 | 2005-03-31 | Glaxo Group Limited | Anti-inflammatory glucocorticoids |
| RU2008100237A (ru) * | 2005-06-14 | 2009-07-20 | Джилид Сайэнс, Инк. (US) | ОБЩИЕ ПРОЛЕКАРСТВЕННЫЕ ФОРМЫ СТЕРОИДОВ И β-АГОНИСТОВ (ВАРИАНТЫ), ВКЛЮЧАЮЩИЙ ИХ АЭРОЗОЛЬНЫЙ СОСТАВ (ВАРИАНТЫ) И СПОСОБ ПРЕДОТВРАЩЕНИЯ И/ИЛИ ЛЕЧЕНИЯ ЛЕГОЧНЫХ ВОСПАЛЕНИЙ И/ИЛИ БРОНХОСТЕНОЗА С ИХ ПОМОЩЬЮ |
| EP2207788A1 (en) | 2007-10-04 | 2010-07-21 | AstraZeneca AB | Steroidal [3, 2-c]pyrazole compounds, with glucocorticoid activity |
| CA2716476A1 (en) * | 2008-02-27 | 2009-09-03 | Astrazeneca Ab | 16 alpha, 17 alpha-acetal glucocorticosteroidal derivatives and their use |
| UY32520A (es) | 2009-04-03 | 2010-10-29 | Astrazeneca Ab | Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides |
| PE20190622A1 (es) | 2016-06-02 | 2019-04-26 | Abbvie Inc | Agonista del receptor de glucocorticoides e inmunoconjugados del mismo |
| MA49796A (fr) | 2017-12-01 | 2020-06-03 | Abbvie Inc | Agoniste du récepteur des glucocorticoïdes et immunoconjugués de celui-ci |
-
1959
- 1959-12-08 BE BE585432A patent/BE585432A/fr unknown
- 1959-12-08 GB GB2319361A patent/GB933868A/en not_active Expired
- 1959-12-08 GB GB4166359A patent/GB933867A/en not_active Expired
- 1959-12-09 ES ES0254059A patent/ES254059A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB933867A (en) | 1963-08-14 |
| BE585432A (fr) | 1960-06-08 |
| GB933868A (en) | 1963-08-14 |
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