ES254141A1 - Procedimiento de preparaciën de nuevas diamidinas derivadas de la difenilurea - Google Patents

Procedimiento de preparaciën de nuevas diamidinas derivadas de la difenilurea

Info

Publication number: ES254141A1
Authority: ES; Spain
Prior art keywords: phosgene; amidino group; give; gives; hydrogen
Prior art date: 1958-12-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0254141A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

May and Baker Ltd

Original Assignee

May and Baker Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1958-12-15

Filing date

1959-12-12

Publication date

1960-03-01

1959-12-12 Application filed by May and Baker Ltd filed Critical May and Baker Ltd

1960-03-01 Publication of ES254141A1 publication Critical patent/ES254141A1/es

Status Expired legal-status Critical Current

Links

125000003739 carbamimidoyl group Chemical group C(N)(=N)* 0.000 abstract 8
YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 6
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
125000004432 carbon atom Chemical group C* 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
238000000034 method Methods 0.000 abstract 4
VGKODZCNDHJSOX-UHFFFAOYSA-N trihydrate;tetrahydrochloride Chemical compound O.O.O.Cl.Cl.Cl.Cl VGKODZCNDHJSOX-UHFFFAOYSA-N 0.000 abstract 4
QMEZUZOCLYUADC-UHFFFAOYSA-N hydrate;dihydrochloride Chemical compound O.Cl.Cl QMEZUZOCLYUADC-UHFFFAOYSA-N 0.000 abstract 3
-1 inorganic acids Chemical class 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
239000000243 solution Substances 0.000 abstract 3
CFKMVGJGLGKFKI-UHFFFAOYSA-N 4-chloro-m-cresol Chemical compound CC1=CC(O)=CC=C1Cl CFKMVGJGLGKFKI-UHFFFAOYSA-N 0.000 abstract 2
YIUIVFFUEVPRIU-UHFFFAOYSA-N 8-chlorotheophylline Chemical compound O=C1N(C)C(=O)N(C)C2=NC(Cl)=N[C]21 YIUIVFFUEVPRIU-UHFFFAOYSA-N 0.000 abstract 2
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
150000007513 acids Chemical class 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004093 cyano group Chemical group *C#N 0.000 abstract 2
239000012153 distilled water Substances 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
238000002347 injection Methods 0.000 abstract 2
239000007924 injection Substances 0.000 abstract 2
150000007522 mineralic acids Chemical class 0.000 abstract 2
ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
CXPBSSIFNALKAT-UHFFFAOYSA-N 1,1-bis(2-chloro-5-cyanophenyl)urea Chemical compound ClC1=CC=C(C=C1N(C(=O)N)C1=CC(=CC=C1Cl)C#N)C#N CXPBSSIFNALKAT-UHFFFAOYSA-N 0.000 abstract 1
VXHWMDKNNXDNNL-UHFFFAOYSA-N 1,1-bis(3-cyanophenyl)urea Chemical compound NC(=O)N(C1=CC(=CC=C1)C#N)C1=CC(=CC=C1)C#N VXHWMDKNNXDNNL-UHFFFAOYSA-N 0.000 abstract 1
ZIFFQNWYXMPRIP-UHFFFAOYSA-N 1,1-bis(5-cyano-2-methoxyphenyl)urea Chemical compound C(#N)C=1C=C(C(=CC1)OC)N(C(=O)N)C1=CC(=CC=C1OC)C#N ZIFFQNWYXMPRIP-UHFFFAOYSA-N 0.000 abstract 1
KRBRYJLBILJHAS-UHFFFAOYSA-N 3-amino-4-chlorobenzonitrile Chemical compound NC1=CC(C#N)=CC=C1Cl KRBRYJLBILJHAS-UHFFFAOYSA-N 0.000 abstract 1
MAYBZGKWHOVSAQ-UHFFFAOYSA-N 3-amino-4-methoxybenzonitrile Chemical compound COC1=CC=C(C#N)C=C1N MAYBZGKWHOVSAQ-UHFFFAOYSA-N 0.000 abstract 1
PHXHYPQRDRRSAN-UHFFFAOYSA-N 3-aminobenzenecarboximidamide;hydrochloride Chemical compound Cl.NC(=N)C1=CC=CC(N)=C1 PHXHYPQRDRRSAN-UHFFFAOYSA-N 0.000 abstract 1
NJXPYZHXZZCTNI-UHFFFAOYSA-N 3-aminobenzonitrile Chemical compound NC1=CC=CC(C#N)=C1 NJXPYZHXZZCTNI-UHFFFAOYSA-N 0.000 abstract 1
XBLPHYSLHRGMNW-UHFFFAOYSA-N 4-chloro-3-nitrobenzonitrile Chemical compound [O-][N+](=O)C1=CC(C#N)=CC=C1Cl XBLPHYSLHRGMNW-UHFFFAOYSA-N 0.000 abstract 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
230000002152 alkylating effect Effects 0.000 abstract 1
229910021529 ammonia Inorganic materials 0.000 abstract 1
LLOHIFXFHGMBNO-UHFFFAOYSA-N azane;2-hydroxyethanesulfonic acid Chemical compound [NH4+].OCCS([O-])(=O)=O LLOHIFXFHGMBNO-UHFFFAOYSA-N 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
229960002242 chlorocresol Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
239000000839 emulsion Substances 0.000 abstract 1
XDYHDLLKHFVVSE-UHFFFAOYSA-N hydrate;dihydrobromide Chemical class O.Br.Br XDYHDLLKHFVVSE-UHFFFAOYSA-N 0.000 abstract 1
229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
NQMRYBIKMRVZLB-UHFFFAOYSA-N methylamine hydrochloride Chemical compound [Cl-].[NH3+]C NQMRYBIKMRVZLB-UHFFFAOYSA-N 0.000 abstract 1
150000007524 organic acids Chemical class 0.000 abstract 1
235000005985 organic acids Nutrition 0.000 abstract 1
YBVNFKZSMZGRAD-UHFFFAOYSA-N pentamidine isethionate Chemical compound OCCS(O)(=O)=O.OCCS(O)(=O)=O.C1=CC(C(=N)N)=CC=C1OCCCCCOC1=CC=C(C(N)=N)C=C1 YBVNFKZSMZGRAD-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1
239000006188 syrup Substances 0.000 abstract 1
235000020357 syrup Nutrition 0.000 abstract 1
239000003826 tablet Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES0254141A 1958-12-15 1959-12-12 Procedimiento de preparaciën de nuevas diamidinas derivadas de la difenilurea Expired ES254141A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB4042858A GB888965A (en)	1958-12-15	1958-12-15	Improvements in or relating to diamidines

Publications (1)

Publication Number	Publication Date
ES254141A1 true ES254141A1 (es)	1960-03-01

Family

ID=10414865

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0254141A Expired ES254141A1 (es)	1958-12-15	1959-12-12	Procedimiento de preparaciën de nuevas diamidinas derivadas de la difenilurea

Country Status (2)

Country	Link
ES (1)	ES254141A1 (es)
GB (1)	GB888965A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10109204A1 (de) *	2001-02-26	2002-09-19	4Sc Ag	Verbindungen zur Behandlung von Protozoen-Erkrankungen
US6949567B2 (en)	2001-02-26	2005-09-27	4Sc Ag	Compounds for the treatment of protozoal diseases

1958
- 1958-12-15 GB GB4042858A patent/GB888965A/en not_active Expired
1959
- 1959-12-12 ES ES0254141A patent/ES254141A1/es not_active Expired

Also Published As

Publication number	Publication date
GB888965A (en)	1962-02-07

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