ES255692A1 - Procedure for the manufacture of tricyclic compounds (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the manufacture of tricyclic compounds (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES255692A1
ES255692A1 ES0255692A ES255692A ES255692A1 ES 255692 A1 ES255692 A1 ES 255692A1 ES 0255692 A ES0255692 A ES 0255692A ES 255692 A ES255692 A ES 255692A ES 255692 A1 ES255692 A1 ES 255692A1
Authority
ES
Spain
Prior art keywords
protected
manufacture
tricyclic compounds
general formula
group formed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0255692A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES255692A1 publication Critical patent/ES255692A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Procedimiento para la fabricación de compuestos tricíclicos el cual comprende el condensar un compuesto escogido en el grupo formado por los compuestos representados por la fórmula general **(Ver fórmula)** en la cual Z representa un radical bivalente escogido en el grupo formado por el oxígeno el azufre y el etileno y productos de los mismos derivados de substitución aromáticonuclear por alquilo halogenoalquilo aralquilo arilo alcoxi aralcoxi ariloxi alquiltio aralquiltio ariltio halógeno acilo protegido amino protegido hidroxi protegido y carboxi protegido con un compuesto representado por la fórmula general M-C≡C-B en la cual M representa un metal alcalino y B representa un radical no aromático monovalente que lleva uno o más grupos amino terciarios el hidrolizar el producto de condensación disgregando cualquier grupo protector que pueda estar presente el hidrogenar si se desea parcial o totalmente la cadena lateral insaturada el tratar si se desea el producto de hidrogenación por un agente deshidratante y el hidrogenar si se desea el enlace doble semicíclico.Process for the manufacture of tricyclic compounds which comprises condensing a compound chosen in the group formed by the compounds represented by the general formula ** (See formula) ** in which Z represents a bivalent radical chosen in the group formed by oxygen sulfur and ethylene and products thereof derivatives of aromatic nuclear substitution by alkyl halogenoalkyl aralkyl aryl alkoxy aralkoxy aryloxy alkylthio aralkylthio arylthio halogen acyl protected amino protected hydroxy protected and carboxy protected with a compound represented by the general formula MC≡CB in which M represents an alkali metal and B represents a monovalent non-aromatic radical bearing one or more tertiary amino groups to hydrolyze the condensation product by disintegrating any protecting groups that may be present on hydrogenate if partially or totally unsaturated side chain to treat if desired the hydrogenation product is desired by u n dehydrating agent and hydrogenating if desired the semi-cyclic double bond.

ES0255692A 1959-02-12 1960-02-11 Procedure for the manufacture of tricyclic compounds (Machine-translation by Google Translate, not legally binding) Expired ES255692A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH6947159 1959-02-12

Publications (1)

Publication Number Publication Date
ES255692A1 true ES255692A1 (en) 1960-08-16

Family

ID=4529539

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0255692A Expired ES255692A1 (en) 1959-02-12 1960-02-11 Procedure for the manufacture of tricyclic compounds (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
BE (1) BE587479A (en)
ES (1) ES255692A1 (en)
FR (1) FR173M (en)
OA (1) OA00933A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB969025A (en) * 1961-04-27 1964-09-09 Koninklijke Pharma Fab Nv Dihydrodibenzocycloheptene derivatives

Also Published As

Publication number Publication date
OA00933A (en) 1968-03-22
FR173M (en) 1961-02-13
BE587479A (en) 1960-08-11

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