ES256088A1 - Procedimiento de preparaciën de una pregnatrieno-diona sustituida - Google Patents

Procedimiento de preparaciën de una pregnatrieno-diona sustituida

Info

Publication number: ES256088A1
Authority: ES; Spain
Prior art keywords: dione; methyl; dihydroxy; pregnane; diene
Prior art date: 1959-02-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0256088A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Laboratoires Francais de Chimiotherapie SA

Laboratoires Francaise de Chimiotherapie

Original Assignee

Laboratoires Francais de Chimiotherapie SA

Laboratoires Francaise de Chimiotherapie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1959-02-27

Filing date

1960-02-26

Publication date

1960-08-16

1960-02-26 Application filed by Laboratoires Francais de Chimiotherapie SA, Laboratoires Francaise de Chimiotherapie filed Critical Laboratoires Francais de Chimiotherapie SA

1960-08-16 Publication of ES256088A1 publication Critical patent/ES256088A1/es

Status Expired legal-status Critical Current

Links

238000002360 preparation method Methods 0.000 title abstract 2
239000003246 corticosteroid Substances 0.000 title 1
229960001334 corticosteroids Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 2
XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
YXHKONLOYHBTNS-UHFFFAOYSA-N Diazomethane Chemical compound C=[N+]=[N-] YXHKONLOYHBTNS-UHFFFAOYSA-N 0.000 abstract 1
238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
150000001340 alkali metals Chemical class 0.000 abstract 1
230000031709 bromination Effects 0.000 abstract 1
238000005893 bromination reaction Methods 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
230000018044 dehydration Effects 0.000 abstract 1
238000006297 dehydration reaction Methods 0.000 abstract 1
238000007269 dehydrobromination reaction Methods 0.000 abstract 1
ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
150000004965 peroxy acids Chemical class 0.000 abstract 1
DNXIASIHZYFFRO-UHFFFAOYSA-N pyrazoline Chemical compound C1CN=NC1 DNXIASIHZYFFRO-UHFFFAOYSA-N 0.000 abstract 1
238000001149 thermolysis Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)

ES0256088A 1959-02-27 1960-02-26 Procedimiento de preparaciën de una pregnatrieno-diona sustituida Expired ES256088A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR787940A FR1227326A (fr)	1959-02-27	1959-02-27	Procédé de préparation d'une pregnatriène-dione substituée

Publications (1)

Publication Number	Publication Date
ES256088A1 true ES256088A1 (es)	1960-08-16

Family

ID=8711821

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0256088A Expired ES256088A1 (es)	1959-02-27	1960-02-26	Procedimiento de preparaciën de una pregnatrieno-diona sustituida

Country Status (5)

Country	Link
BE (1)	BE588076A (es)
CH (1)	CH371447A (es)
ES (1)	ES256088A1 (es)
FR (1)	FR1227326A (es)
GB (1)	GB934704A (es)

1959
- 1959-02-27 FR FR787940A patent/FR1227326A/fr not_active Expired
1960
- 1960-02-18 CH CH184960A patent/CH371447A/fr unknown
- 1960-02-22 GB GB619360A patent/GB934704A/en not_active Expired
- 1960-02-26 BE BE588076A patent/BE588076A/fr unknown
- 1960-02-26 ES ES0256088A patent/ES256088A1/es not_active Expired

Also Published As

Publication number	Publication date
BE588076A (fr)	1960-08-26
GB934704A (en)	1963-08-21
CH371447A (fr)	1963-08-31
FR1227326A (fr)	1960-08-19

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