ES2571111T3 - Método de diagnóstico para predicción de la respuesta de un paciente a la quimioviroterapia o radioviroterapia - Google Patents

Método de diagnóstico para predicción de la respuesta de un paciente a la quimioviroterapia o radioviroterapia

Info

Publication number
ES2571111T3
ES2571111T3 ES11746432T ES11746432T ES2571111T3 ES 2571111 T3 ES2571111 T3 ES 2571111T3 ES 11746432 T ES11746432 T ES 11746432T ES 11746432 T ES11746432 T ES 11746432T ES 2571111 T3 ES2571111 T3 ES 2571111T3
Authority
ES
Spain
Prior art keywords
patient
chemovirotherapy
radiovirotherapy
predicting
response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11746432T
Other languages
English (en)
Inventor
Nathalia Giese
Jens Werner
Markus Büchler
Thomas Giese
Laurent Däffler
Celina Cziepluch
Jean Rommelaere
Zahari Raykov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
German Cancer Research Center
Universität Heidelberg
University Hospital Heidelberg
Original Assignee
German Cancer Research Center
Universität Heidelberg
University Hospital Heidelberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by German Cancer Research Center, Universität Heidelberg, University Hospital Heidelberg filed Critical German Cancer Research Center
Application granted granted Critical
Publication of ES2571111T3 publication Critical patent/ES2571111T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un método de diagnóstico para predecir la respuesta de un paciente a la quimioviroterapia o radioviroterapia, que comprende (a) exponer células de tumor primario de una muestra de tumor obtenida de un paciente a dosis diferentes de (i) un parvovirus y (ii) un agente quimioterapéutico o radioterapia; y (b) determinar la reducción de la expresión o concentración de ISG15 durante periodos de tiempo variables.
ES11746432T 2010-04-30 2011-04-29 Método de diagnóstico para predicción de la respuesta de un paciente a la quimioviroterapia o radioviroterapia Active ES2571111T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10004592A EP2383577A1 (en) 2010-04-30 2010-04-30 Diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy
PCT/EP2011/002154 WO2011134670A2 (en) 2010-04-30 2011-04-29 Diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy

Publications (1)

Publication Number Publication Date
ES2571111T3 true ES2571111T3 (es) 2016-05-24

Family

ID=42782289

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11746432T Active ES2571111T3 (es) 2010-04-30 2011-04-29 Método de diagnóstico para predicción de la respuesta de un paciente a la quimioviroterapia o radioviroterapia

Country Status (8)

Country Link
US (1) US9664684B2 (es)
EP (2) EP2383577A1 (es)
JP (1) JP5725463B2 (es)
AU (1) AU2011247360B2 (es)
CA (1) CA2797553C (es)
DK (1) DK2564201T3 (es)
ES (1) ES2571111T3 (es)
WO (1) WO2011134670A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040175362A1 (en) 1999-05-12 2004-09-09 Curiel David T. Infectivity-enhanced conditionally-replicative adenovirus and uses thereof
US10238698B2 (en) 2012-01-25 2019-03-26 Dnatrix, Inc. Biomarkers and combination therapies using oncolytic virus and immunomodulation
WO2013116778A2 (en) 2012-02-02 2013-08-08 Board Of Regents Immunogenic adenovirus
CN103941009B (zh) * 2014-04-14 2016-06-29 河北工程大学 用于牛羊早期妊娠诊断的isg15胶体金试纸条及其制作方法
EP3568145B1 (en) * 2017-01-13 2025-06-11 Mayo Foundation for Medical Education and Research Materials and methods for treating cancer
EP3657172A1 (en) * 2018-11-22 2020-05-27 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Method for predicting the clinical response of oncolytic parvovirus h1 (h-1pv) treatment in a patient suspected of suffering from cancer by measuring the expression levels of laminins and/or galectins as biomarkers in a patient´s sample
CN109694871B (zh) * 2019-01-16 2022-06-10 中国药科大学 抗人isg15蛋白抗体基因及其应用
CN120225206A (zh) * 2022-09-16 2025-06-27 株式会社韩国原子力工学 具有远端效应的用于预防或者治疗癌症的组合物，以及使用该组合物预防或者治疗癌症的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ536102A (en) * 2002-05-09 2008-01-31 Oncolytics Biotech Inc Oncolytic viruses, in particular reovirus, for reducing pain associated with proliferative disorders, particularly with the growth of a solid tumour mass
US20090136479A1 (en) * 2004-06-28 2009-05-28 The Johns Hopkins University Ubiquitin-like protein isg15 for hiv inhibition
JP4651495B2 (ja) 2005-10-14 2011-03-16 日本製粉株式会社 Ｉｓｇ１５タンパク質と特異的に反応するモノクローナル抗体及びそれを産生するハイブリドーマ並びに癌およびウイルス感染の検出方法
US8435731B2 (en) * 2006-01-11 2013-05-07 Colorado State University Research Foundation Markers for viral infections and other inflammatory responses
US20100111874A1 (en) * 2007-03-19 2010-05-06 University Of Medicine And Dentistry Of New Jresey Method of cancer detection and treatment
ES2402138T3 (es) * 2007-12-28 2013-04-29 Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts Terapia contra el cáncer con un parvovirus combinado con quimioterapia

Also Published As

Publication number Publication date
EP2564201A2 (en) 2013-03-06
CA2797553C (en) 2017-10-17
JP5725463B2 (ja) 2015-05-27
US9664684B2 (en) 2017-05-30
CA2797553A1 (en) 2011-11-03
AU2011247360A1 (en) 2012-11-08
WO2011134670A3 (en) 2012-01-12
DK2564201T3 (en) 2016-05-17
EP2564201B1 (en) 2016-03-09
AU2011247360B2 (en) 2016-03-10
WO2011134670A2 (en) 2011-11-03
US20130101989A1 (en) 2013-04-25
JP2013524823A (ja) 2013-06-20
EP2383577A1 (en) 2011-11-02

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