ES258378A1 - Procedimiento para la preparacion de nuevos deerivados de la insoindolina - Google Patents

Procedimiento para la preparacion de nuevos deerivados de la insoindolina

Info

Publication number: ES258378A1
Authority: ES; Spain
Prior art keywords: general formula; compound; compounds; reacting; prepared
Prior art date: 1959-05-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0258378A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee

JR Geigy AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1959-05-27

Filing date

1960-05-25

Publication date

1960-12-01

1960-05-25 Application filed by JR Geigy AG filed Critical JR Geigy AG

1960-12-01 Publication of ES258378A1 publication Critical patent/ES258378A1/es

Status Expired legal-status Critical Current

Links

GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical class C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 10
RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical compound O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 abstract 4
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
229910052794 bromium Chemical group 0.000 abstract 2
229910052801 chlorine Inorganic materials 0.000 abstract 2
239000000460 chlorine Substances 0.000 abstract 2
239000012954 diazonium Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
230000000802 nitrating effect Effects 0.000 abstract 2
-1 phthalic acid ester halides Chemical class 0.000 abstract 2
235000010269 sulphur dioxide Nutrition 0.000 abstract 2
239000004291 sulphur dioxide Substances 0.000 abstract 2
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
238000009833 condensation Methods 0.000 abstract 1
230000005494 condensation Effects 0.000 abstract 1
150000001879 copper Chemical class 0.000 abstract 1
ORTQZVOHEJQUHG-UHFFFAOYSA-L copper(II) chloride Chemical compound Cl[Cu]Cl ORTQZVOHEJQUHG-UHFFFAOYSA-L 0.000 abstract 1
150000001989 diazonium salts Chemical class 0.000 abstract 1
239000002934 diuretic Substances 0.000 abstract 1
230000001882 diuretic effect Effects 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
150000005171 halobenzenes Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000001077 hypotensive effect Effects 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
150000003951 lactams Chemical class 0.000 abstract 1
150000002596 lactones Chemical class 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
238000006396 nitration reaction Methods 0.000 abstract 1
XNGIFLGASWRNHJ-UHFFFAOYSA-N o-dicarboxybenzene Natural products OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 abstract 1
LGRFSURHDFAFJT-UHFFFAOYSA-N phthalic anhydride Chemical class C1=CC=C2C(=O)OC(=O)C2=C1 LGRFSURHDFAFJT-UHFFFAOYSA-N 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
230000000894 saliuretic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES0258378A 1959-05-27 1960-05-25 Procedimiento para la preparacion de nuevos deerivados de la insoindolina Expired ES258378A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH7362959A CH374670A (de)	1959-05-27	1959-05-27	Verfahren zur Herstellung von neuen Isoindolinderivaten

Publications (1)

Publication Number	Publication Date
ES258378A1 true ES258378A1 (es)	1960-12-01

Family

ID=4532757

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES0258378A Expired ES258378A1 (es)	1959-05-27	1960-05-25	Procedimiento para la preparacion de nuevos deerivados de la insoindolina
ES0258380A Expired ES258380A1 (es)	1959-05-27	1960-05-25	Procedimiento para la preparacion de nuevos derivados de la isoindolina

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES0258380A Expired ES258380A1 (es)	1959-05-27	1960-05-25	Procedimiento para la preparacion de nuevos derivados de la isoindolina

Country Status (5)

Country	Link
BE (1)	BE591292A (fr)
CH (1)	CH374670A (fr)
DE (1)	DE1238031B (fr)
ES (2)	ES258378A1 (fr)
GB (1)	GB916101A (fr)

1959
- 1959-05-27 CH CH7362959A patent/CH374670A/de unknown
1960
- 1960-05-25 ES ES0258378A patent/ES258378A1/es not_active Expired
- 1960-05-25 DE DE1960G0029755 patent/DE1238031B/de active Pending
- 1960-05-25 ES ES0258380A patent/ES258380A1/es not_active Expired
- 1960-05-26 GB GB1863760A patent/GB916101A/en not_active Expired
- 1960-05-27 BE BE591292A patent/BE591292A/fr unknown

Also Published As

Publication number	Publication date
ES258380A1 (es)	1960-12-01
BE591292A (fr)	1960-11-28
CH374670A (de)	1964-01-31
GB916101A (en)	1963-01-23
DE1238031B (de)	1967-04-06

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