ES2584319T3 - Microesferas de almidón hidrolizado con ligandos endógenos cargados - Google Patents

Microesferas de almidón hidrolizado con ligandos endógenos cargados Download PDF

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Publication number
ES2584319T3
ES2584319T3 ES10834831.9T ES10834831T ES2584319T3 ES 2584319 T3 ES2584319 T3 ES 2584319T3 ES 10834831 T ES10834831 T ES 10834831T ES 2584319 T3 ES2584319 T3 ES 2584319T3
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ES
Spain
Prior art keywords
microspheres
wound healing
hydrolyzed starch
wound
conjugated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10834831.9T
Other languages
English (en)
Spanish (es)
Inventor
Malin MALMSJÖ
Eddie Thordarson
Sten Peter Apell
Peter Fyhr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Magle AB
Original Assignee
Magle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magle AB filed Critical Magle AB
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Publication of ES2584319T3 publication Critical patent/ES2584319T3/es
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/003—Crosslinking of starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/02—Esters
    • C08B31/04—Esters of organic acids, e.g. alkenyl-succinated starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES10834831.9T 2009-12-04 2010-11-17 Microesferas de almidón hidrolizado con ligandos endógenos cargados Active ES2584319T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0901521 2009-12-04
SE0901521 2009-12-04
PCT/SE2010/051268 WO2011068455A1 (en) 2009-12-04 2010-11-17 Microspheres of hydrolysed starch with endogenous, charged ligands

Publications (1)

Publication Number Publication Date
ES2584319T3 true ES2584319T3 (es) 2016-09-27

Family

ID=44115153

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10834831.9T Active ES2584319T3 (es) 2009-12-04 2010-11-17 Microesferas de almidón hidrolizado con ligandos endógenos cargados

Country Status (20)

Country Link
US (2) US9708416B2 (lt)
EP (1) EP2506859B1 (lt)
JP (1) JP5767239B2 (lt)
KR (1) KR20120130166A (lt)
CN (1) CN102740862B (lt)
AU (1) AU2010327380B2 (lt)
BR (1) BR112012012997B8 (lt)
CA (1) CA2781593C (lt)
ES (1) ES2584319T3 (lt)
HR (1) HRP20160835T1 (lt)
HU (1) HUE030071T2 (lt)
IL (1) IL220069A (lt)
LT (1) LT2506859T (lt)
PL (1) PL2506859T3 (lt)
PT (1) PT2506859T (lt)
RU (2) RU2725890C2 (lt)
SI (1) SI2506859T1 (lt)
UA (1) UA110776C2 (lt)
WO (1) WO2011068455A1 (lt)
ZA (1) ZA201203497B (lt)

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US10639396B2 (en) 2015-06-11 2020-05-05 Microvention, Inc. Polymers
US8757077B2 (en) 2009-04-30 2014-06-24 Technip France Spar mooring line sharing method and system
AU2010313530B2 (en) 2009-10-26 2015-12-17 Microvention, Inc. Embolization device constructed from expansile polymer
LT2506859T (lt) 2009-12-04 2016-09-26 Magle Ab Hidrolizuoto krakmolo mikrosferos su endogeniniais įkrautais ligandais
WO2012145431A2 (en) 2011-04-18 2012-10-26 Microvention, Inc. Embolic devices
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JP6480327B2 (ja) 2012-06-14 2019-03-06 マイクロベンション インコーポレイテッドＭｉｃｒｏｖｅｎｔｉｏｎ， Ｉｎｃ． ポリマー治療組成物
EP2906254B1 (en) 2012-10-15 2020-01-08 Microvention, Inc. Polymeric treatment compositions
CA2923741C (en) 2013-09-19 2022-06-07 Microvention, Inc. Polymer films
US9546236B2 (en) 2013-09-19 2017-01-17 Terumo Corporation Polymer particles
US9688788B2 (en) 2013-11-08 2017-06-27 Terumo Corporation Polymer particles
WO2015153996A1 (en) 2014-04-03 2015-10-08 Micro Vention, Inc. Embolic devices
US10226533B2 (en) 2014-04-29 2019-03-12 Microvention, Inc. Polymer filaments including pharmaceutical agents and delivering same
WO2015167751A1 (en) 2014-04-29 2015-11-05 Microvention, Inc. Polymers
US9907880B2 (en) 2015-03-26 2018-03-06 Microvention, Inc. Particles
CN105567626A (zh) * 2016-02-24 2016-05-11 冯玉萍 一种细胞培养用微载体及其制备方法和应用
US10368874B2 (en) 2016-08-26 2019-08-06 Microvention, Inc. Embolic compositions
WO2018064390A1 (en) 2016-09-28 2018-04-05 Microvention, Inc. Polymer particles
CN106955375A (zh) * 2016-12-07 2017-07-18 凯文蔡司淀粉科技有限公司 一种用于微创手术止血的包含植物多聚糖的医疗装置
CN107335090B (zh) * 2017-07-11 2020-09-01 李徐奇 一种具有创面修复作用的生物相容性止血材料及其制备方法
CN107243085A (zh) * 2017-07-12 2017-10-13 南京续航生物材料科技有限公司 一种体内降解时间可控的止血材料及其制备方法
WO2019074965A1 (en) 2017-10-09 2019-04-18 Microvention, Inc. EMBOLIC RADIOACTIVE LIQUID
PL3501552T3 (pl) 2017-12-20 2020-10-19 Magle Chemoswed Holding Ab Wodna kompozycja do wykrywania wycieku płynu ustrojowego
CN111053943A (zh) * 2018-10-16 2020-04-24 中科院大连化学物理研究所张家港产业技术研究院有限公司 一种止血材料的制备方法及其应用
CN110538344B (zh) * 2019-10-09 2020-08-04 北京诺康达医药科技股份有限公司 医用可降解止血材料及其制备方法
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
US12161777B2 (en) 2020-07-02 2024-12-10 Davol Inc. Flowable hemostatic suspension
MX2023007767A (es) 2020-12-28 2023-07-07 Davol Inc Materiales hemostaticos secos en polvo reactivos que comprenden una proteina y un agente de entrelazado a base de polietilenglicol modificado multifuncional.
JP7690377B2 (ja) * 2021-10-29 2025-06-10 株式会社Ｓｃｒｅｅｎホールディングス 画像処理方法、受精卵の評価方法、コンピュータープログラムおよび記録媒体
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Also Published As

Publication number Publication date
CN102740862A (zh) 2012-10-17
EP2506859B1 (en) 2016-05-04
BR112012012997B1 (pt) 2020-12-01
LT2506859T (lt) 2016-09-26
RU2012125200A (ru) 2014-01-20
IL220069A (en) 2017-02-28
UA110776C2 (uk) 2016-02-25
HRP20160835T1 (hr) 2016-09-23
US20120244198A1 (en) 2012-09-27
JP2013512895A (ja) 2013-04-18
AU2010327380B2 (en) 2014-11-27
PT2506859T (pt) 2016-08-12
RU2016122487A3 (lt) 2019-11-29
BR112012012997A2 (pt) 2017-03-01
ZA201203497B (en) 2013-08-28
JP5767239B2 (ja) 2015-08-19
BR112012012997B8 (pt) 2021-05-25
CA2781593C (en) 2018-01-23
CA2781593A1 (en) 2011-06-09
EP2506859A1 (en) 2012-10-10
RU2016122487A (ru) 2018-11-29
SI2506859T1 (sl) 2016-10-28
HK1172268A1 (en) 2013-04-19
AU2010327380A1 (en) 2012-05-31
KR20120130166A (ko) 2012-11-29
EP2506859A4 (en) 2013-10-23
CN102740862B (zh) 2014-12-24
US9708416B2 (en) 2017-07-18
HUE030071T2 (en) 2017-04-28
US20180022833A1 (en) 2018-01-25
WO2011068455A1 (en) 2011-06-09
RU2725890C2 (ru) 2020-07-07
PL2506859T3 (pl) 2016-11-30

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