ES260469A1 - Mejoras en los aparatos para estudiar particulas en fluido de suspensiën - Google Patents
Mejoras en los aparatos para estudiar particulas en fluido de suspensiënInfo
- Publication number
- ES260469A1 ES260469A1 ES0260469A ES260469A ES260469A1 ES 260469 A1 ES260469 A1 ES 260469A1 ES 0260469 A ES0260469 A ES 0260469A ES 260469 A ES260469 A ES 260469A ES 260469 A1 ES260469 A1 ES 260469A1
- Authority
- ES
- Spain
- Prior art keywords
- particles
- analyzing device
- particle analyzing
- channel
- suspension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 239000000725 suspension Substances 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N15/131—Details
- G01N15/132—Circuits
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N2015/135—Electrodes
- G01N2015/136—Scanning electrodes
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Measurement Of Radiation (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
Mejoras en aparatos para estudiar partículas en un fluido de suspensión, caracterizadas porque en el cual la impedancia total de un canal de pequeñas dimensiones en dicha suspensión es variada por un movimiento relativo entre dichas partículas y dicho canal como un resultado de propiedades eléctricas contrastantes de dichas partículas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US834860A US3259842A (en) | 1959-08-19 | 1959-08-19 | Particle analyzing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES260469A1 true ES260469A1 (es) | 1961-02-01 |
Family
ID=25267997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0260469A Expired ES260469A1 (es) | 1959-08-19 | 1960-08-18 | Mejoras en los aparatos para estudiar particulas en fluido de suspensiën |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US3259842A (es) |
| BE (1) | BE594258A (es) |
| ES (1) | ES260469A1 (es) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3461030A (en) * | 1965-10-22 | 1969-08-12 | Beloit Corp | Determination of fiber characteristics in paper making |
| US3444464A (en) * | 1965-11-26 | 1969-05-13 | Coulter Electronics | Multiple aperture fittings for particle analyzing apparatus |
| US3535644A (en) * | 1967-07-28 | 1970-10-20 | Nasa | Pulse amplitude and width detector |
| US3675768A (en) * | 1969-03-17 | 1972-07-11 | Gildardo Legorreta Sanchez | Method and apparatus for classifying and segregating particles with electrical and optical means |
| US3699319A (en) * | 1971-03-10 | 1972-10-17 | Robert H Berg | Average volume digital computer and digital volume totalizer for cells and particles |
| US3733548A (en) * | 1971-04-28 | 1973-05-15 | Coulter Electronics | Apparatus and method for measuring particle concentration of a suspension passing through a sensing zone |
| US3781674A (en) * | 1971-07-22 | 1973-12-25 | Coulter Electronics | Noise discriminating circuitry and method for electronic particle study apparatus |
| US3733547A (en) * | 1972-01-04 | 1973-05-15 | Coulter Electronics | Method and apparatus for measuring particle concentration in a fluid suspension of particles |
| US3781675A (en) * | 1972-04-27 | 1973-12-25 | Gen Science Corp | Self priming conductivity cell |
| US3790883A (en) * | 1972-05-09 | 1974-02-05 | Coulter Electronics | Particle study apparatus having improved particle resolution means |
| US3944917A (en) * | 1973-08-13 | 1976-03-16 | Coulter Electronics, Inc. | Electrical sensing circuitry for particle analyzing device |
| US3921006A (en) * | 1974-09-16 | 1975-11-18 | Coulter Electronics | Particle counting apparatus including isolated manometer |
| US4278936A (en) * | 1980-02-05 | 1981-07-14 | Coulter Electronics, Inc. | Biological cell parameter change test method and apparatus |
| US4453266A (en) * | 1980-04-21 | 1984-06-05 | Rush-Presbyterian-St. Luke's Medical Center | Method and apparatus for measuring mean cell volume of red blood cells |
| US4374644A (en) * | 1981-04-06 | 1983-02-22 | Coulter Electronics, Inc. | Blood cell volume monitoring |
| US4535284A (en) * | 1981-07-10 | 1985-08-13 | Coulter Electronics, Inc. | High and low frequency analysis of osmotic stress of cells |
| JPS5829450A (ja) * | 1981-08-18 | 1983-02-21 | 株式会社豊田中央研究所 | ヘマトクリツト測定装置 |
| US4450435A (en) * | 1981-11-30 | 1984-05-22 | Bobby Dencil James | Analog debris alarm |
| US4555662A (en) * | 1983-03-03 | 1985-11-26 | Limca Research Inc. | Method and apparatus for the detection and measurement of particulates in molten metal |
| US4600880A (en) * | 1983-03-03 | 1986-07-15 | Limca Research Inc. | Apparatus for the detection and measurement of particulates in molten metal |
| JPS60213850A (ja) * | 1984-04-09 | 1985-10-26 | Hitachi Ltd | 粒子分析装置 |
| US4751179A (en) * | 1984-05-31 | 1988-06-14 | Coulter Electronics, Inc. | Method and reagents for differential determination of four populations of leukocytes in blood |
| US4775833A (en) * | 1986-10-03 | 1988-10-04 | Coulter Electronics, Inc. | Lodged debris detector for a particle analyzer |
| US5907240A (en) * | 1997-05-12 | 1999-05-25 | Cdc Technologies, Inc. | Method and apparatus for cell differentiation by measuring apparent cell size, membrane integrity and intracellular complexity |
| US6111398A (en) * | 1997-07-03 | 2000-08-29 | Coulter International Corp. | Method and apparatus for sensing and characterizing particles |
| US6175227B1 (en) | 1997-07-03 | 2001-01-16 | Coulter International Corp. | Potential-sensing method and apparatus for sensing and characterizing particles by the Coulter principle |
| US6259242B1 (en) | 1999-05-26 | 2001-07-10 | Coulter International Corp. | Apparatus incorporating a sensing conduit in conductive material and method of use thereof for sensing and characterizing particles |
| US7732127B2 (en) * | 2002-12-20 | 2010-06-08 | Acea Biosciences, Inc. | Dynamic monitoring of cell adhesion and spreading using the RT-CES system |
| US7560269B2 (en) * | 2002-12-20 | 2009-07-14 | Acea Biosciences, Inc. | Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays |
| US7468255B2 (en) * | 2002-12-20 | 2008-12-23 | Acea Biosciences | Method for assaying for natural killer, cytotoxic T-lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology |
| WO2004010102A2 (en) * | 2002-07-20 | 2004-01-29 | Acea Biosciences, Inc. | Impedance based apparatuses and methods for analyzing cells and particles |
| US7470533B2 (en) * | 2002-12-20 | 2008-12-30 | Acea Biosciences | Impedance based devices and methods for use in assays |
| US8263375B2 (en) | 2002-12-20 | 2012-09-11 | Acea Biosciences | Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology |
| US8206903B2 (en) | 2002-12-20 | 2012-06-26 | Acea Biosciences | Device and method for electroporation-based delivery of molecules into cells and dynamic monitoring of cell responses |
| US7192752B2 (en) | 2002-12-20 | 2007-03-20 | Acea Biosciences | Real time electronic cell sensing systems and applications for cell-based assays |
| US10215748B2 (en) | 2002-12-20 | 2019-02-26 | Acea Biosciences, Inc. | Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways |
| US9612234B2 (en) | 2008-05-05 | 2017-04-04 | Acea Biosciences, Inc. | Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (RTCA) cardio instruments |
| US10539523B2 (en) | 2002-12-20 | 2020-01-21 | Acea Biosciences, Inc. | System and method for monitoring cardiomyocyte beating, viability, morphology, and electrophysiological properties |
| US11346797B2 (en) | 2002-12-20 | 2022-05-31 | Agilent Technologies, Inc. | System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties |
| US10551371B2 (en) | 2003-11-10 | 2020-02-04 | Acea Biosciences, Inc. | System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function |
| WO2006037325A1 (en) * | 2004-10-01 | 2006-04-13 | Chempaq A/S | A method for calibrating a particle counting apparatus |
| US8041515B2 (en) * | 2006-09-20 | 2011-10-18 | Acea Biosciences, Inc. | Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents |
| CA2723223C (en) | 2008-05-05 | 2017-06-06 | Acea Biosciences, Inc. | Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution |
| EP2422181A1 (en) * | 2009-04-24 | 2012-02-29 | Beckman Coulter, Inc. | Method of characterizing particles |
| US12066428B2 (en) | 2015-11-20 | 2024-08-20 | Agilent Technologies, Inc. | Cell-substrate impedance monitoring of cancer cells |
| CN110582569B (zh) | 2017-03-03 | 2024-04-02 | 安捷伦科技有限公司 | 用于iPSC和ESC衍生的心肌细胞的功能成熟的方法和系统 |
| US20220195487A1 (en) * | 2019-04-18 | 2022-06-23 | BEIJING XINJI JINNUO MEDICAL EQUIPMENT Co.,Ltd. | Method for Measuring Inhibition of Bacteria by Antibacterial Drug, and Bacterial Counting Device and Method Thereof |
| USD941488S1 (en) | 2020-02-07 | 2022-01-18 | Agilent Technologies, Inc. | Instrument for analyzing biological cells |
| US20210301245A1 (en) | 2020-03-29 | 2021-09-30 | Agilent Technologies, Inc. | Systems and methods for electronically and optically monitoring biological samples |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2536617A (en) * | 1945-02-27 | 1951-01-02 | Barton L Weller | Direct current negative feedback amplifier |
| US2550990A (en) * | 1946-04-08 | 1951-05-01 | Weston Electrical Instr Corp | Direct current amplifier |
| US2573523A (en) * | 1946-06-24 | 1951-10-30 | Gen Electric | Feedback amplifier |
| US2680227A (en) * | 1947-06-19 | 1954-06-01 | Atomic Energy Commission | Polaroscope |
| US2589133A (en) * | 1948-01-13 | 1952-03-11 | John Hays Hammond Jr | Electrical filter |
| US2541198A (en) * | 1948-04-14 | 1951-02-13 | Irving R Brenholdt | Amplifier |
| US2656508A (en) * | 1949-08-27 | 1953-10-20 | Wallace H Coulter | Means for counting particles suspended in a fluid |
| BE501088A (es) * | 1950-02-07 | |||
| US2869121A (en) * | 1950-09-18 | 1959-01-13 | Martin Co | Synchronization system |
| US2671200A (en) * | 1950-10-18 | 1954-03-02 | Jerome F Lederer | Safety signal device |
| US2970259A (en) * | 1951-04-23 | 1961-01-31 | Phillips Petroleum Co | Flame detector |
| US2731520A (en) * | 1952-03-10 | 1956-01-17 | Phillips Petroleum Co | Pulse-amplitude measuring circuit compensated for varying frequency |
| US2760184A (en) * | 1952-08-22 | 1956-08-21 | Tidewater Oil Company | System for detecting solids in gaseous streams |
| US2825872A (en) * | 1953-06-23 | 1958-03-04 | Vilbiss Co | Particle analyzing apparatus |
| US2719287A (en) * | 1953-07-31 | 1955-09-27 | William W Bartlett | Electronic gas flowmeter |
| US2811591A (en) * | 1954-08-30 | 1957-10-29 | Raytheon Mfg Co | Feedback network compensations |
| US2919399A (en) * | 1955-01-05 | 1959-12-29 | Jr James R Brown | Automatic impedance plotter |
| US2839619A (en) * | 1955-04-05 | 1958-06-17 | Johnstone Charles Wilkin | Pulse amplifier |
| US2943264A (en) * | 1955-05-24 | 1960-06-28 | Ibm | Pulse reshaper |
| US3001175A (en) * | 1956-02-29 | 1961-09-19 | Walter P Christoph | Hydraulic rectifying bridge circuit |
| US2901609A (en) * | 1956-05-02 | 1959-08-25 | Westinghouse Air Brake Co | Differentiator |
| US3023397A (en) * | 1957-09-23 | 1962-02-27 | Jr Herbert B Reed | Hydraulic phase discriminator |
| CA686707A (en) * | 1960-09-13 | 1964-05-19 | Holzer Johann | Time correcting regenerative pulse repeater |
-
1959
- 1959-08-19 US US834860A patent/US3259842A/en not_active Expired - Lifetime
-
1960
- 1960-08-18 ES ES0260469A patent/ES260469A1/es not_active Expired
- 1960-08-19 BE BE594258A patent/BE594258A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3259842A (en) | 1966-07-05 |
| BE594258A (fr) | 1961-02-20 |
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