ES2636441T8 - Un procedimiento novedoso para la síntesis de polifenoles - Google Patents
Un procedimiento novedoso para la síntesis de polifenoles Download PDFInfo
- Publication number
- ES2636441T8 ES2636441T8 ES12739384.1T ES12739384T ES2636441T8 ES 2636441 T8 ES2636441 T8 ES 2636441T8 ES 12739384 T ES12739384 T ES 12739384T ES 2636441 T8 ES2636441 T8 ES 2636441T8
- Authority
- ES
- Spain
- Prior art keywords
- polyphenols
- synthesis
- novel procedure
- novel
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000008442 polyphenolic compounds Chemical class 0.000 title 1
- 235000013824 polyphenols Nutrition 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN196DE2011 | 2011-01-27 | ||
| INDE01962011 | 2011-01-27 | ||
| PCT/IN2012/000052 WO2012101652A2 (en) | 2011-01-27 | 2012-01-24 | A novel process for synthesis of polyphenols |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2636441T3 ES2636441T3 (es) | 2017-10-05 |
| ES2636441T8 true ES2636441T8 (es) | 2018-12-14 |
Family
ID=46581222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12739384.1T Active ES2636441T3 (es) | 2011-01-27 | 2012-01-24 | Un procedimiento novedoso para la síntesis de polifenoles |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9428482B2 (es) |
| EP (1) | EP2668176B1 (es) |
| JP (1) | JP5890846B2 (es) |
| CN (1) | CN103582635B (es) |
| ES (1) | ES2636441T3 (es) |
| TW (1) | TWI697489B (es) |
| WO (1) | WO2012101652A2 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105026384A (zh) * | 2013-01-26 | 2015-11-04 | 斯法尔制药私人有限公司 | 合成儿茶素的新方法 |
| WO2014162320A2 (en) | 2013-04-04 | 2014-10-09 | Sphaera Pharma Pvt. Ltd. | Novel analogues of epicatechin and related polyphenols |
| CN106714770B (zh) | 2014-07-23 | 2024-04-19 | 斯法尔制药私人有限公司 | 羟基类固醇化合物、其中间体、制备方法、组合物及其用途 |
| EP3472176B1 (en) * | 2016-06-21 | 2024-05-15 | Sphaera Pharma Pvt. Ltd. | Utility of (+) epicatechin and their analogs |
| CN105949161B (zh) * | 2016-06-28 | 2018-05-15 | 温州大学 | 一种3-芳巯基黄酮化合物的制备方法 |
| CN106946835B (zh) * | 2017-04-25 | 2019-03-01 | 广州科技职业技术学院 | 橙皮素酯化物及其制备方法和应用 |
| EP3677577A4 (en) | 2017-08-28 | 2021-04-28 | NBC Meshtec, Inc. | POLYPHENOL PRODUCTION PROCESS |
| BR112021007684A2 (pt) | 2018-10-24 | 2021-07-27 | Epirium Bio Inc. | cocristal, composição farmacêutica, métodos para tratar uma doença ou distúrbio que se beneficiaria da modificação da cadeia de transporte de elétrons, para reduzir os níveis de triglicerídeos, para tratar uma doença ou distúrbio selecionado a partir do grupo que consiste em uma síndrome metabólica, diabetes tipo ii, uma hiperlipidemia congênita e hiperlipidemia induzida por drogas, para tratar uma condição relacionada à disfunção mitocondrial, para melhorar o desempenho esportivo, resistência, construção de forma ou força muscular, ou facilitar a recuperação dos efeitos do treinamento ou competição e para tratar ou prevenir distrofinopatia, sarcoglicanopatia ou disferlinopatia, processo para preparar um cocristal, e, uso de um cocristal |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2122608B (en) * | 1982-06-01 | 1985-10-02 | Zyma Sa | (+)-cyanidan-3-ol derivatives |
| EP0445819B1 (en) * | 1990-03-08 | 2001-08-22 | Fuji Photo Film Co., Ltd. | Positive type photoresist composition |
| US6476241B1 (en) * | 2000-09-05 | 2002-11-05 | Mars Incorporated | Synthesis of 4α-arylepicatechins |
| CN100400535C (zh) * | 2003-03-03 | 2008-07-09 | 三荣源有限公司 | 脂联素表达促进剂 |
| JP5339664B2 (ja) * | 2004-02-13 | 2013-11-13 | 花王株式会社 | Ａｍｐｋ活性化剤 |
| JP2006083105A (ja) * | 2004-09-16 | 2006-03-30 | Ito En Ltd | 血液流動性改善剤および飲食物 |
| CN101248057A (zh) * | 2005-06-29 | 2008-08-20 | 马尔斯公司 | (+)-儿茶素、(-)-表儿茶素、(-)-儿茶素、(+)-表儿茶素以及它们的5,7,3＇,4＇-四-o-苄基类似物的制备 |
| WO2008153945A2 (en) * | 2007-06-06 | 2008-12-18 | University Of South Florida | Nutraceutical co-crystal compositions |
| JP5382676B2 (ja) * | 2007-12-07 | 2014-01-08 | 国立大学法人名古屋大学 | アントシアニジン類の製造方法 |
-
2012
- 2012-01-24 JP JP2013551012A patent/JP5890846B2/ja not_active Expired - Fee Related
- 2012-01-24 EP EP12739384.1A patent/EP2668176B1/en active Active
- 2012-01-24 CN CN201280010653.7A patent/CN103582635B/zh active Active
- 2012-01-24 WO PCT/IN2012/000052 patent/WO2012101652A2/en not_active Ceased
- 2012-01-24 ES ES12739384.1T patent/ES2636441T3/es active Active
- 2012-01-24 US US13/981,279 patent/US9428482B2/en active Active
- 2012-01-30 TW TW101102826A patent/TWI697489B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012101652A2 (en) | 2012-08-02 |
| EP2668176A4 (en) | 2014-08-27 |
| TW201309662A (zh) | 2013-03-01 |
| CN103582635A (zh) | 2014-02-12 |
| US9428482B2 (en) | 2016-08-30 |
| EP2668176A2 (en) | 2013-12-04 |
| ES2636441T3 (es) | 2017-10-05 |
| EP2668176B1 (en) | 2017-05-17 |
| CN103582635B (zh) | 2019-02-19 |
| TWI697489B (zh) | 2020-07-01 |
| JP2014509312A (ja) | 2014-04-17 |
| JP5890846B2 (ja) | 2016-03-22 |
| US20140031421A1 (en) | 2014-01-30 |
| WO2012101652A3 (en) | 2012-12-27 |
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