ES2636441T8 - Un procedimiento novedoso para la síntesis de polifenoles - Google Patents
Un procedimiento novedoso para la síntesis de polifenoles Download PDFInfo
- Publication number
- ES2636441T8 ES2636441T8 ES12739384.1T ES12739384T ES2636441T8 ES 2636441 T8 ES2636441 T8 ES 2636441T8 ES 12739384 T ES12739384 T ES 12739384T ES 2636441 T8 ES2636441 T8 ES 2636441T8
- Authority
- ES
- Spain
- Prior art keywords
- polyphenols
- synthesis
- novel procedure
- novel
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000008442 polyphenolic compounds Chemical class 0.000 title 1
- 235000013824 polyphenols Nutrition 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pyrane Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| INDE01962011 | 2011-01-27 | ||
| IN196DE2011 | 2011-01-27 | ||
| PCT/IN2012/000052 WO2012101652A2 (en) | 2011-01-27 | 2012-01-24 | A novel process for synthesis of polyphenols |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2636441T3 ES2636441T3 (es) | 2017-10-05 |
| ES2636441T8 true ES2636441T8 (es) | 2018-12-14 |
Family
ID=46581222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES12739384.1T Active ES2636441T3 (es) | 2011-01-27 | 2012-01-24 | Un procedimiento novedoso para la síntesis de polifenoles |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9428482B2 (es) |
| EP (1) | EP2668176B1 (es) |
| JP (1) | JP5890846B2 (es) |
| CN (1) | CN103582635B (es) |
| ES (1) | ES2636441T3 (es) |
| TW (1) | TWI697489B (es) |
| WO (1) | WO2012101652A2 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9556140B2 (en) | 2013-01-26 | 2017-01-31 | Sphaera Pharma Pvt. Ltd. | Approach for synthesis of catechins |
| CN105283179A (zh) * | 2013-04-04 | 2016-01-27 | 斯法尔制药私人有限公司 | 表儿茶素及相关多酚的新类似物 |
| US10618933B2 (en) | 2014-07-23 | 2020-04-14 | Epirium Bio Inc. | Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof |
| US10898465B2 (en) | 2016-06-21 | 2021-01-26 | Epirium Bio Inc. | Utility of (+) epicatechin and their analogs |
| CN105949161B (zh) * | 2016-06-28 | 2018-05-15 | 温州大学 | 一种3-芳巯基黄酮化合物的制备方法 |
| CN106946835B (zh) * | 2017-04-25 | 2019-03-01 | 广州科技职业技术学院 | 橙皮素酯化物及其制备方法和应用 |
| WO2019044672A1 (ja) * | 2017-08-28 | 2019-03-07 | 株式会社Nbcメッシュテック | ポリフェノールの製造方法 |
| CA3117466A1 (en) | 2018-10-24 | 2020-04-30 | Epirium Bio Inc. | Co-crystals comprising epicatechin and a carboxy-n-heterocyclic co-crystal former |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2122608B (en) * | 1982-06-01 | 1985-10-02 | Zyma Sa | (+)-cyanidan-3-ol derivatives |
| EP0445819B1 (en) * | 1990-03-08 | 2001-08-22 | Fuji Photo Film Co., Ltd. | Positive type photoresist composition |
| US6476241B1 (en) * | 2000-09-05 | 2002-11-05 | Mars Incorporated | Synthesis of 4α-arylepicatechins |
| EP1602652A1 (en) * | 2003-03-03 | 2005-12-07 | San-Ei Gen F.F.I., Inc. | Adiponectin expression promoter |
| JP5339664B2 (ja) * | 2004-02-13 | 2013-11-13 | 花王株式会社 | Ampk活性化剤 |
| JP2006083105A (ja) * | 2004-09-16 | 2006-03-30 | Ito En Ltd | 血液流動性改善剤および飲食物 |
| EP1896443A1 (en) * | 2005-06-29 | 2008-03-12 | Mars, Incorporated | Preparation of (+)-catechin, (-)-epicatechin, (-)-catechin, (+)-epicatechin, and their 5,7,3',4'-tetra-o-benzyl analogues |
| US20100204204A1 (en) * | 2007-06-06 | 2010-08-12 | University Of South Florida | Nutraceutical co-crystal compositions |
| JP5382676B2 (ja) * | 2007-12-07 | 2014-01-08 | 国立大学法人名古屋大学 | アントシアニジン類の製造方法 |
-
2012
- 2012-01-24 JP JP2013551012A patent/JP5890846B2/ja not_active Expired - Fee Related
- 2012-01-24 ES ES12739384.1T patent/ES2636441T3/es active Active
- 2012-01-24 US US13/981,279 patent/US9428482B2/en active Active
- 2012-01-24 EP EP12739384.1A patent/EP2668176B1/en active Active
- 2012-01-24 CN CN201280010653.7A patent/CN103582635B/zh active Active
- 2012-01-24 WO PCT/IN2012/000052 patent/WO2012101652A2/en not_active Ceased
- 2012-01-30 TW TW101102826A patent/TWI697489B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TW201309662A (zh) | 2013-03-01 |
| WO2012101652A3 (en) | 2012-12-27 |
| ES2636441T3 (es) | 2017-10-05 |
| US20140031421A1 (en) | 2014-01-30 |
| EP2668176A4 (en) | 2014-08-27 |
| EP2668176A2 (en) | 2013-12-04 |
| JP2014509312A (ja) | 2014-04-17 |
| WO2012101652A2 (en) | 2012-08-02 |
| CN103582635A (zh) | 2014-02-12 |
| CN103582635B (zh) | 2019-02-19 |
| JP5890846B2 (ja) | 2016-03-22 |
| TWI697489B (zh) | 2020-07-01 |
| US9428482B2 (en) | 2016-08-30 |
| EP2668176B1 (en) | 2017-05-17 |
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