ES2654621T3 - Utilización cosmética de la asociación de un extracto de germen de algarroba y de cafeína como agente activo adelgazante - Google Patents

Utilización cosmética de la asociación de un extracto de germen de algarroba y de cafeína como agente activo adelgazante Download PDF

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Publication number
ES2654621T3
ES2654621T3 ES13818289.4T ES13818289T ES2654621T3 ES 2654621 T3 ES2654621 T3 ES 2654621T3 ES 13818289 T ES13818289 T ES 13818289T ES 2654621 T3 ES2654621 T3 ES 2654621T3
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Prior art keywords
caffeine
association
extract
cosmetic use
carob bean
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ES13818289.4T
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English (en)
Inventor
Nouha Domloge
Frédérique PORTOLAN
Anne Clement
Jean Marie BOTTO
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ISP Investments LLC
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ISP Investments LLC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645Proteins of vegetable origin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9711Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9717Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/06Preparations for care of the skin for countering cellulitis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Utilización cosmética de la asociación de un extracto peptídico de germen de algarroba (Ceratonia siliqua L.) y de cafeína, o uno de sus derivados, como agente activo adelgazante.

Description

imagen1
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[0112] La evaluación de la eficacia se realiza mediante comparaciones de las mediciones en T0 y en T 28 días, siendo cada voluntario su propio testigo. Resultados: [0113] En las condiciones experimentales, después de 28 días de aplicación, se observa una disminución media 5 significativa de -2,2 cm de la circunferencia del abdomen, una disminución media significativa de -1,2 cm de la
circunferencia superior del muslo y una disminución media significativa del volumen de los troncos de los muslos. [0114] La serie de datos sigue una distribución normal. El análisis estadístico utiliza una prueba t de Student para datos emparejados, en la que P<0,05 se considera significativo.
[0115] Por otra parte, un cuestionario ha permitido determinar que la mayoría de los voluntarios consideró las 10 zonas tratadas más lisas y más firmes y el aspecto de piel de naranja atenuado.
Conclusión: [0116] La aplicación dos veces al día de la asociación del extracto de algarroba según el ejemplo 1 y de cafeína al 2 % durante 1 mes permite un adelgazamiento significativo de los muslos y del vientre, así como una atenuación del aspecto de piel de naranja.
15 Ejemplo 6: Preparación de composiciones 1 Crema adelgazante 1
[0117]
Fase
Componente % másico
A
Agua purificada 38,84
A
Metilpropanodiol 3,00
A
Gliceret-26 3,00
B
Glicerina 100 % veg. 2,00
B
Goma de xantana estándar 0,3
C
Isododecano 15,00
C
DC 1503 Fluido 3,0
C
Acetato de tocoferol 0,5
D
Pemulen TR1 0,5
D
Synthalen K 0,3
E
NA 4 EDTA 0,1
E
L Arginina 0,2
E
Agua purificada 1,4
F
Ácido salicílico 0,4
F
Alcohol agrícola 96 % 10,00
G
Agua purificada 4,7
G
Hidróxido de sodio 0,3
H
PF pomelo E 9509056/07 0,3
I
Agua purificada 8,58
J
Cafeína 2,0
K
Sol. Col. FDC azul N1 0,1 % sin conservante 0,640
12
Fase
Componente % másico
K
Sol. Col. FDC amarillo 5 al 0,1 % en MP DIOL 0,440
L
Bodyfit 2,5
L
Extracto de algarroba según el ejemplo 1 2,00
2 Crema adelgazante 2
[0118]
Fase
Componente % másico
A
Agua purificada 49,615
A
Hidróxido de sodio 0,110
A
Metilpropanodiol 4,00
B
Ácido salicílico 0,4
C
Cafeína 1,5
D
NA 4 EDTA 0,1
E
Synthalen K 1,0
F
Alcohol cetílico 20 OE 1,0
F
Coco-caprilato caprato 9,00
F
Alcohol cetílico 2,00
F
Manteca de karité 100 % veg. 2,00
F
Cera de abeja 100 % natural 2,00
F
Acetato de tocoferol 0,5
F
Alcohol estearílico OV 1,00
F
Dimeticona 20CST 2,00
G
Hidróxido de sodio 0,350
G
Agua purificada 2,00
H
Sulfato de dextrano 0,5
H
Extracto de algarroba según el ejemplo 1 2,00
H
Agua purificada 3,00
I
Rutina 0,05
I
Propilenglicol 4,00
J
Alcohol agrícola 96 % 11,00
J
Sol. Col. FDC azul N1 0,1 % sin conservante 0,275
J
PF revitalizante TER G111 25975 0,3
13

Claims (1)

  1. imagen1
ES13818289.4T 2012-12-11 2013-12-10 Utilización cosmética de la asociación de un extracto de germen de algarroba y de cafeína como agente activo adelgazante Active ES2654621T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1203364 2012-12-11
FR1203364A FR2999080B1 (fr) 2012-12-11 2012-12-11 Utilisation cosmetique de l'association d'un extrait de de germe de caroube et de cafeine en tant qu'agent actif amincissant
PCT/FR2013/053022 WO2014091147A2 (fr) 2012-12-11 2013-12-10 Utilisation cosmetique de l'association d'un extrait de germe de caroube et de cafeine en tant qu'agent actif amincissant

Publications (1)

Publication Number Publication Date
ES2654621T3 true ES2654621T3 (es) 2018-02-14

Family

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Application Number Title Priority Date Filing Date
ES13818289.4T Active ES2654621T3 (es) 2012-12-11 2013-12-10 Utilización cosmética de la asociación de un extracto de germen de algarroba y de cafeína como agente activo adelgazante

Country Status (7)

Country Link
US (1) US9962329B2 (es)
EP (1) EP2931232B1 (es)
JP (1) JP2016502976A (es)
CN (1) CN104936574B (es)
ES (1) ES2654621T3 (es)
FR (1) FR2999080B1 (es)
WO (1) WO2014091147A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20210266T1 (hr) * 2014-06-26 2021-04-02 Giuliani S.P.A. Pripravak prikladan za očuvanje fiziološkog stanja kože i kose i ponovnu uspostavu njihovih regenerativnih funkcija
JP6527715B2 (ja) * 2015-02-27 2019-06-05 株式会社東洋新薬 黒生姜含有組成物
CN109394622B (zh) * 2018-12-10 2021-04-16 西安海蓝化妆品有限公司 一种瘦腿精华乳液

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU86934A1 (fr) 1987-06-30 1989-03-08 Oreal Composition cosmetique a action anti-cellulitique et amin-cissante dont le principe actif est une 1-hydroxyalkylxanthine
FR2609395B1 (fr) 1988-02-23 1992-01-10 Serobiologiques Lab Sa Utilisation de bases xanthiques comme principe actif d'une composition pharmaceutique, notamment dermatologique, ou cosmetique, composition notamment utile comme matiere de base pour la preparation de composition pharmaceutique ou cosmetique et composition pharmaceutique ou cosmetique ainsi preparee
FR2669537B1 (fr) 1990-11-28 1993-02-19 Oreal Composition amincissante a base d'alpha-2-bloqueurs.
FR2671487B1 (fr) 1991-01-14 1993-03-19 Oreal Utilisation d'un facteur de croissance dans une composition amincissante.
FR2720604B1 (fr) * 1994-06-03 1996-09-06 Meyhall Chemical Ag Fraction de germe de caroube à haute teneur en protéine.
DE10009424A1 (de) 2000-02-28 2001-09-06 Henkel Kgaa Verwendung von Flavonen oder Isoflavonen zur Cellulite-Behandlung
AU2001253070A1 (en) * 2000-03-31 2001-10-15 Jonathan Ingram Isoflavones for treatment of obesity
FR2858769B1 (fr) 2003-08-13 2006-02-10 Soc Extraction Principes Actif Utilisation d'un peptide comme principe actif amincissant
JP2004307358A (ja) * 2003-04-02 2004-11-04 Daiya Seiyaku Kk 外用ゲル基剤及び容器充填型パッド材
FR2859104A1 (fr) * 2003-08-29 2005-03-04 Saint Laurent Parfums Molecules a activite anti-adipogenique sur cellules adipocytaires humaines
US20050186290A1 (en) * 2003-12-10 2005-08-25 L'oreal Use of aquaglyceroporin modulators as slimming agent
FR2867683B1 (fr) * 2004-03-22 2012-12-21 Lm Cosmetics Compositions cosmetiques ou dermatologiques et leurs applications
FR2879924B1 (fr) 2004-12-23 2007-06-15 Soc Extraction Principes Actif Composition cosmetique amincissante
FR2884418B1 (fr) 2005-04-15 2008-11-21 Soc Extraction Principes Actif Utilisation d'un peptide comme principe actif amincissant
US7579027B2 (en) * 2005-09-20 2009-08-25 Grethe Stoa Birketvedt Composition for treating obesity comprising extract from white kidney beans, red kidney beans, and green tea leaves
US20080004283A1 (en) * 2005-12-06 2008-01-03 Menarini Ricerche S.P.A. Pharmaceutical Compositions for the Treatment of Cellulite
FR2954697B1 (fr) * 2009-12-24 2016-11-04 Isp Investments Inc Composition cosmetique et/ou pharmaceutique comprenant un extrait de caroube en tant qu'agent actif activateur de l'expression des aquaporines

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Publication number Publication date
JP2016502976A (ja) 2016-02-01
US20150306023A1 (en) 2015-10-29
US9962329B2 (en) 2018-05-08
WO2014091147A2 (fr) 2014-06-19
FR2999080A1 (fr) 2014-06-13
EP2931232B1 (fr) 2017-10-04
CN104936574A (zh) 2015-09-23
CN104936574B (zh) 2018-01-16
WO2014091147A3 (fr) 2014-08-14
EP2931232A2 (fr) 2015-10-21
FR2999080B1 (fr) 2015-03-20
HK1213787A1 (zh) 2016-07-15

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