ES268859A1 - Procedimiento para la obtenciën de nuevos derivados de pirazina - Google Patents
Procedimiento para la obtenciën de nuevos derivados de pirazinaInfo
- Publication number
- ES268859A1 ES268859A1 ES0268859A ES268859A ES268859A1 ES 268859 A1 ES268859 A1 ES 268859A1 ES 0268859 A ES0268859 A ES 0268859A ES 268859 A ES268859 A ES 268859A ES 268859 A1 ES268859 A1 ES 268859A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- aminopyrazine
- alkyl
- chloro
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003216 pyrazines Chemical class 0.000 title 1
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 229910019213 POCl3 Inorganic materials 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- JPMJUTNVPDDMKZ-UHFFFAOYSA-N 3-chloro-5-methylpyrazin-2-amine Chemical compound CC1=CN=C(N)C(Cl)=N1 JPMJUTNVPDDMKZ-UHFFFAOYSA-N 0.000 abstract 2
- CGJYSLPJPPINSM-UHFFFAOYSA-N 3-chloro-6-methylpyrazin-2-amine Chemical compound CC1=CN=C(Cl)C(N)=N1 CGJYSLPJPPINSM-UHFFFAOYSA-N 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- CAWHJQAVHZEVTJ-UHFFFAOYSA-N methylpyrazine Chemical compound CC1=CN=CC=N1 CAWHJQAVHZEVTJ-UHFFFAOYSA-N 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- XFTQRUTUGRCSGO-UHFFFAOYSA-N pyrazin-2-amine Chemical compound NC1=CN=CC=N1 XFTQRUTUGRCSGO-UHFFFAOYSA-N 0.000 abstract 2
- HEOLCUBUYOTJDB-UHFFFAOYSA-N 3-amino-5-methyl-1h-pyrazin-2-one Chemical compound CC1=CN=C(O)C(N)=N1 HEOLCUBUYOTJDB-UHFFFAOYSA-N 0.000 abstract 1
- YVGTVIOWXKGPRN-UHFFFAOYSA-N 3-amino-6-methyl-1h-pyrazin-2-one Chemical compound CC1=CN=C(N)C(=O)N1 YVGTVIOWXKGPRN-UHFFFAOYSA-N 0.000 abstract 1
- WUPAWCXFTGKASP-UHFFFAOYSA-N 5-methyl-2-oxo-1h-pyrazine-3-carboxamide Chemical compound CC1=CN=C(O)C(C(N)=O)=N1 WUPAWCXFTGKASP-UHFFFAOYSA-N 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- STQLOVWBLNDJOX-UHFFFAOYSA-N N-(3-nitropyrazin-2-yl)benzenesulfonamide Chemical compound [N+](=O)([O-])C=1C(=NC=CN1)NS(=O)(=O)C1=CC=CC=C1 STQLOVWBLNDJOX-UHFFFAOYSA-N 0.000 abstract 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 abstract 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- -1 p-nitrobenzenesulphonyl halide Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
- C07D241/22—Benzenesulfonamido pyrazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1210860 | 1960-07-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES268859A1 true ES268859A1 (es) | 1961-12-16 |
Family
ID=11139461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0268859A Expired ES268859A1 (es) | 1960-07-08 | 1961-07-07 | Procedimiento para la obtenciën de nuevos derivados de pirazina |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE605897A (es) |
| ES (1) | ES268859A1 (es) |
| GB (1) | GB922725A (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE943301C (de) * | 1951-10-17 | 1956-05-17 | Busch Jaeger Duerener Metall | Fassung fuer Leuchtstoffroehren |
| CA2209465C (en) * | 1996-07-11 | 2008-04-29 | Lonza Ag | Process for preparing 3-alkoxy-5-alkylpyrazin-2-amines |
| CA2241933C (en) | 1997-07-03 | 2008-10-07 | Lonza Ag | Process for preparing alkoxypyrazine derivatives |
-
1961
- 1961-07-03 GB GB2396861A patent/GB922725A/en not_active Expired
- 1961-07-07 BE BE605897A patent/BE605897A/fr unknown
- 1961-07-07 ES ES0268859A patent/ES268859A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE605897A (fr) | 1962-01-08 |
| GB922725A (en) | 1963-04-03 |
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