ES2690392A1 - Material inyectable para la regeneración del cartílago articular - Google Patents

Material inyectable para la regeneración del cartílago articular Download PDF

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Publication number
ES2690392A1
ES2690392A1 ES201830730A ES201830730A ES2690392A1 ES 2690392 A1 ES2690392 A1 ES 2690392A1 ES 201830730 A ES201830730 A ES 201830730A ES 201830730 A ES201830730 A ES 201830730A ES 2690392 A1 ES2690392 A1 ES 2690392A1
Authority
ES
Spain
Prior art keywords
injectable material
regeneration
cartilage
relates
articular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES201830730A
Other languages
English (en)
Other versions
ES2690392B2 (es
Inventor
José Luis Gómez Ribelles
Gloria GALLEGO FERRER
Carmen ANTOLINOS TURPÍN
María SANCHO-TELLO VALLS
Carmen CARDA BATALLA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Politecnica de Valencia
Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBEREHD
Universitat de Valencia
Centro de Investigacion Biomedica en Red CIBER
Fundacion Incliva
Original Assignee
Universidad Politecnica de Valencia
Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBEREHD
Universitat de Valencia
Centro de Investigacion Biomedica en Red CIBER
Fundacion Incliva
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Politecnica de Valencia, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBEREHD, Universitat de Valencia, Centro de Investigacion Biomedica en Red CIBER, Fundacion Incliva filed Critical Universidad Politecnica de Valencia
Priority to ES201830730A priority Critical patent/ES2690392B2/es
Publication of ES2690392A1 publication Critical patent/ES2690392A1/es
Application granted granted Critical
Publication of ES2690392B2 publication Critical patent/ES2690392B2/es
Priority to PCT/ES2019/070505 priority patent/WO2020016476A1/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)

Abstract

Material inyectable para la regeneración del cartílago articular.#La invención se refiere a un material inyectable cuyo implante en el lugar de un defecto de cartílago se puede combinar con una técnica de estimulación del hueso subcondral, más particularmente, se refiere a un material inyectable de microesferas de plasma rico en plaquetas obtenidas a partir de una extracción de sangre del propio paciente y otras microesferas sintéticas, preferentemente, de un polímero biorreabsorbible, y su uso como soporte de la regeneración de cartílago.

Description

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Claims (1)

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ES201830730A 2018-07-19 2018-07-19 Material inyectable para la regeneracion del cartilago articular Active ES2690392B2 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES201830730A ES2690392B2 (es) 2018-07-19 2018-07-19 Material inyectable para la regeneracion del cartilago articular
PCT/ES2019/070505 WO2020016476A1 (es) 2018-07-19 2019-07-18 Material inyectable para la regeneración del cartílago articular

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201830730A ES2690392B2 (es) 2018-07-19 2018-07-19 Material inyectable para la regeneracion del cartilago articular

Publications (2)

Publication Number Publication Date
ES2690392A1 true ES2690392A1 (es) 2018-11-20
ES2690392B2 ES2690392B2 (es) 2019-07-05

Family

ID=64317152

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201830730A Active ES2690392B2 (es) 2018-07-19 2018-07-19 Material inyectable para la regeneracion del cartilago articular

Country Status (2)

Country Link
ES (1) ES2690392B2 (es)
WO (1) WO2020016476A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4445905A1 (en) * 2023-04-14 2024-10-16 Santxa Research S.L.U. Plasma enriched in platelets and plasma molecules
ES3055176A1 (es) * 2025-08-14 2026-02-10 Univ Valencia Politecnica Procedimiento de obtención de un material granulado de micropartículas, material granulado de micropartículas y uso del mismo para el almacenamiento y liberación de componentes celulares

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002000272A2 (en) * 2000-06-29 2002-01-03 Biosyntech Canada Inc. Composition and method for the repair and regeneration of cartilage and other tissues
WO2006023803A2 (en) * 2004-08-20 2006-03-02 Artes Medical, Inc. Methods of administering microparticles combined with autologous body components
WO2011150328A1 (en) * 2010-05-27 2011-12-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
EP2591812A1 (en) * 2011-11-14 2013-05-15 University of Twente, Institute for Biomedical Technology and Technical Medicine (MIRA) A dextran-based tissuelette containing platelet-rich plasma lysate for cartilage repair
WO2013116791A1 (en) * 2012-02-02 2013-08-08 Mosaic Biosciences, Inc. Biomaterials for delivery of blood extracts and methods of using same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002000272A2 (en) * 2000-06-29 2002-01-03 Biosyntech Canada Inc. Composition and method for the repair and regeneration of cartilage and other tissues
WO2006023803A2 (en) * 2004-08-20 2006-03-02 Artes Medical, Inc. Methods of administering microparticles combined with autologous body components
WO2011150328A1 (en) * 2010-05-27 2011-12-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
EP2591812A1 (en) * 2011-11-14 2013-05-15 University of Twente, Institute for Biomedical Technology and Technical Medicine (MIRA) A dextran-based tissuelette containing platelet-rich plasma lysate for cartilage repair
WO2013116791A1 (en) * 2012-02-02 2013-08-08 Mosaic Biosciences, Inc. Biomaterials for delivery of blood extracts and methods of using same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MEHEUX CARLOS J ET AL. Efficacy of Intra-articular Platelet-Rich Plasma Injections in Knee Osteoarthritis: A Systematic Review. Arthroscopy MAR 2016. , 29/02/2016, Vol. 32, Páginas 495-505 ISSN 0749-8063(print) ISSN 1526-3231(electronic), (DOI: doi:10.1016/j.arthro.2015.08.005) Todo el documento, en especial página 503, tabla 4. *
SAITO M ET AL. Intraarticular administration of platelet-rich plasma with biodegradable gelatin hydrogel microspheres prevents osteoarthritis progression in the rabbit knee.. Clinical and experimental rheumatology Italy. , 28/02/2009, Vol. 27, Páginas 201 - 207 ISSN 0392-856X (Print), (DOI: pubmed:19473558) todo el documento *
SANCHO-TELLO M ET AL. Poly(l-lactic acid) microspheres induce ï¿¿in vivoï¿¿ articular cartilage regeneration in rabbits. Artificial Organs 20170901 Blackwell Publishing Inc. nld. , 01/09/2017, Vol. 41, Páginas A79 ISSN 1525-1594 (print), Todo el documento. *

Also Published As

Publication number Publication date
WO2020016476A1 (es) 2020-01-23
ES2690392B2 (es) 2019-07-05

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