ES271787A1 - Procedimiento para la preparaciën de derivados pirazinicos - Google Patents
Procedimiento para la preparaciën de derivados pirazinicosInfo
- Publication number
- ES271787A1 ES271787A1 ES0271787A ES271787A ES271787A1 ES 271787 A1 ES271787 A1 ES 271787A1 ES 0271787 A ES0271787 A ES 0271787A ES 271787 A ES271787 A ES 271787A ES 271787 A1 ES271787 A1 ES 271787A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- methoxy
- chloro
- preparation
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YEAICDDXRUOCKJ-UHFFFAOYSA-N 4-amino-n-pyrazin-2-ylbenzenesulfonamide Chemical class C1=CC(N)=CC=C1S(=O)(=O)NC1=CN=CC=N1 YEAICDDXRUOCKJ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- -1 alkali metal salt Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 abstract 2
- VDCVWLBXEWOGCO-UHFFFAOYSA-N 2,3,5-trichloropyrazine Chemical compound ClC1=CN=C(Cl)C(Cl)=N1 VDCVWLBXEWOGCO-UHFFFAOYSA-N 0.000 abstract 1
- FJBBJUZPLKNMNK-UHFFFAOYSA-N 4-amino-N-(5-chloro-3-methoxypyrazin-2-yl)benzenesulfonamide Chemical compound ClC=1N=C(C(=NC1)NS(=O)(=O)C1=CC=C(C=C1)N)OC FJBBJUZPLKNMNK-UHFFFAOYSA-N 0.000 abstract 1
- QXNZMDMHGJRESJ-UHFFFAOYSA-N 4-amino-n-(3,5-dichloropyrazin-2-yl)benzenesulfonamide Chemical compound C1=CC(N)=CC=C1S(=O)(=O)NC1=NC=C(Cl)N=C1Cl QXNZMDMHGJRESJ-UHFFFAOYSA-N 0.000 abstract 1
- PVLPKSOHLYTQQR-UHFFFAOYSA-N N-[4-[(5-chloro-3-methoxypyrazin-2-yl)sulfamoyl]phenyl]acetamide Chemical compound C(C)(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=C(N=C1OC)Cl PVLPKSOHLYTQQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 230000003385 bacteriostatic effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- KXRZBTAEDBELFD-UHFFFAOYSA-N sulfamethopyrazine Chemical compound COC1=NC=CN=C1NS(=O)(=O)C1=CC=C(N)C=C1 KXRZBTAEDBELFD-UHFFFAOYSA-N 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
- C07D241/22—Benzenesulfonamido pyrazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1928460 | 1960-11-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES271787A1 true ES271787A1 (es) | 1962-07-01 |
Family
ID=11156395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0271787A Expired ES271787A1 (es) | 1960-11-07 | 1961-11-06 | Procedimiento para la preparaciën de derivados pirazinicos |
Country Status (4)
| Country | Link |
|---|---|
| BR (1) | BR6133829D0 (es) |
| CH (1) | CH425802A (es) |
| ES (1) | ES271787A1 (es) |
| GB (2) | GB981096A (es) |
-
1961
- 1961-01-01 BR BR13382961D patent/BR6133829D0/pt unknown
- 1961-09-29 GB GB3507161A patent/GB981096A/en not_active Expired
- 1961-09-29 GB GB4887162A patent/GB981097A/en not_active Expired
- 1961-11-02 CH CH1270661A patent/CH425802A/de unknown
- 1961-11-06 ES ES0271787A patent/ES271787A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB981096A (en) | 1965-01-20 |
| CH425802A (de) | 1966-12-15 |
| BR6133829D0 (pt) | 1973-05-31 |
| GB981097A (en) | 1965-01-20 |
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