ES271902A1 - Basic ethers - Google Patents

Basic ethers

Info

Publication number
ES271902A1
ES271902A1 ES0271902A ES271902A ES271902A1 ES 271902 A1 ES271902 A1 ES 271902A1 ES 0271902 A ES0271902 A ES 0271902A ES 271902 A ES271902 A ES 271902A ES 271902 A1 ES271902 A1 ES 271902A1
Authority
ES
Spain
Prior art keywords
carbon atoms
acid addition
alkyl radical
pharmaceutical preparations
radical containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0271902A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Pharmaceutische Fabrieken NV
Original Assignee
Koninklijke Pharmaceutische Fabrieken NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Pharmaceutische Fabrieken NV filed Critical Koninklijke Pharmaceutische Fabrieken NV
Publication of ES271902A1 publication Critical patent/ES271902A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:1003449/C2/1> (wherein R1 represents an alkyl radical containing less than seven carbon atoms, R2, R3, R4 and R5 each represents a hydrogen atom or an alkyl radical containing less than five carbon atoms, and the total number of carbon atoms in R1, R2, R3, R4 and R5 is at least three) and non-toxic acid addition salts thereof, pharmaceutical preparations containing them, and their preparation by reacting a compound of the formula <FORM:1003449/C2/2> with a 2-dimethylaminoethyl halide, optionally followed by acid addition salt formation. The carbinol starting materials may be prepared by standard methods. The compounds of the invention are analgesics and diuretics and may be administered orally in the form of pharmaceutical preparations (e.g. syrups, elixirs, tablets and capsules) containing them together with a carrier. Specification 651,710 is referred to.
ES0271902A 1960-11-11 1961-11-10 Basic ethers Expired ES271902A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL257859 1960-11-11

Publications (1)

Publication Number Publication Date
ES271902A1 true ES271902A1 (en) 1962-04-01

Family

ID=19752691

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0271902A Expired ES271902A1 (en) 1960-11-11 1961-11-10 Basic ethers

Country Status (7)

Country Link
BR (1) BR6134092D0 (en)
CH (1) CH404665A (en)
DE (1) DE1445115A1 (en)
DK (1) DK105158C (en)
ES (1) ES271902A1 (en)
FI (1) FI43076B (en)
GB (1) GB1003449A (en)

Also Published As

Publication number Publication date
DE1445115A1 (en) 1968-10-24
FI43076B (en) 1970-10-01
DK105158C (en) 1966-08-29
BR6134092D0 (en) 1973-07-10
GB1003449A (en) 1965-09-02
CH404665A (en) 1965-12-31

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