ES2721401T3 - Dispositivo de inhalación - Google Patents

Dispositivo de inhalación Download PDF

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Publication number
ES2721401T3
ES2721401T3 ES15774606T ES15774606T ES2721401T3 ES 2721401 T3 ES2721401 T3 ES 2721401T3 ES 15774606 T ES15774606 T ES 15774606T ES 15774606 T ES15774606 T ES 15774606T ES 2721401 T3 ES2721401 T3 ES 2721401T3
Authority
ES
Spain
Prior art keywords
inhalation device
aqueous solution
delivery device
spray nozzle
nozzle unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15774606T
Other languages
English (en)
Inventor
Nenad Bencic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xellia Pharmaceuticals ApS
Original Assignee
Xellia Pharmaceuticals ApS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xellia Pharmaceuticals ApS filed Critical Xellia Pharmaceuticals ApS
Application granted granted Critical
Publication of ES2721401T3 publication Critical patent/ES2721401T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manipulator (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un dispositivo de administración pulmonar, que comprende una unidad de boquilla de pulverización y un cartucho que contiene una solución acuosa que comprende de 80 a 400 mg A/mL de una polimixina sulfometilada.
ES15774606T 2014-10-03 2015-10-01 Dispositivo de inhalación Active ES2721401T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462059748P 2014-10-03 2014-10-03
PCT/EP2015/072736 WO2016050933A1 (en) 2014-10-03 2015-10-01 Inhalation device

Publications (1)

Publication Number Publication Date
ES2721401T3 true ES2721401T3 (es) 2019-07-31

Family

ID=54249495

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15774606T Active ES2721401T3 (es) 2014-10-03 2015-10-01 Dispositivo de inhalación

Country Status (27)

Country Link
US (1) US11033602B2 (es)
EP (2) EP3200762B1 (es)
JP (1) JP6626890B2 (es)
KR (1) KR102494511B1 (es)
CN (1) CN106999542B (es)
AU (1) AU2015326847B2 (es)
BR (1) BR112017006816A2 (es)
CA (1) CA2962120C (es)
CO (1) CO2017004442A2 (es)
CY (1) CY1121803T1 (es)
DK (1) DK3200762T3 (es)
ES (1) ES2721401T3 (es)
HR (1) HRP20190747T1 (es)
HU (1) HUE044289T2 (es)
IL (1) IL251480B (es)
LT (1) LT3200762T (es)
MX (1) MX2017004175A (es)
PH (1) PH12017500538A1 (es)
PL (1) PL3200762T3 (es)
PT (1) PT3200762T (es)
RS (1) RS58792B1 (es)
RU (1) RU2702335C2 (es)
SG (1) SG11201702666SA (es)
SI (1) SI3200762T1 (es)
SM (1) SMT201900275T1 (es)
TR (1) TR201906108T4 (es)
WO (1) WO2016050933A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106794221B (zh) 2014-10-03 2021-12-10 埃克斯利亚制药有限公司 组合物
CN112546030A (zh) * 2019-09-26 2021-03-26 盈科瑞（天津）创新医药研究有限公司 一种吸入用多粘菌素e甲磺酸钠溶液及其制备方法
US12178841B2 (en) * 2021-08-05 2024-12-31 Zambon S.P.A. Treatment of non-cystic fibrosis bronchiectasis

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1062895A (en) 1962-12-13 1967-03-22 Wellcome Found Sulphomethyl derivatives of polymxin
FR1586834A (es) 1968-02-12 1970-03-06
DE1906699A1 (de) 1968-02-12 1970-02-05 Pfizer Neue Polymyxinderivate und Verfahren zu deren Herstellung
AU611030B2 (en) 1988-04-07 1991-05-30 Edward Shanbrom Non-thrombogenic intravascular time release catheter
SE9201246D0 (sv) 1992-04-21 1992-04-21 Kabi Pharmacia Ab Injection cartridge arrangement
NL9401260A (nl) 1993-11-12 1995-06-01 Cornelis Johannes Maria Van Ri Membraan voor microfiltratie, ultrafiltratie, gasscheiding en katalyse, werkwijze ter vervaardiging van een dergelijk membraan, mal ter vervaardiging van een dergelijk membraan, alsmede diverse scheidingssystemen omvattende een dergelijk membraan.
CA2242335A1 (en) 1996-11-15 1998-05-22 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
US5767068A (en) * 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
ES2261735T3 (es) 2001-05-18 2006-11-16 Chiron Corporation Sistema para la administracion de una formulacion de tobramicina.
US20040022740A1 (en) 2001-07-10 2004-02-05 Baker William R. Macrolide formulations for inhalation and methods of treatment of endobronchial infections
DK1340506T3 (da) 2002-03-01 2007-05-07 Chiesi Farma Spa Sammensætninger omfattende pulmonære tensider og et polymyxin med forbedrede overfladeegenskaber
WO2008025560A1 (en) * 2006-09-01 2008-03-06 Pari Pharma Gmbh Methods for taste masking of nebulised compositions for nasal and pulmonary inhalation therapy
US20080066739A1 (en) * 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
US8329645B2 (en) * 2008-02-08 2012-12-11 Northern Antibiotics Ltd. Polymyxin derivatives and uses thereof
DE102008030267B3 (de) 2008-06-19 2010-01-28 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Verfahren zum Befüllen von Doppelkammersystemen in vorsterilisierbaren Trägersystemen und vorsterilisierbares Trägersystem
BR112012008236A2 (pt) 2009-10-08 2016-03-08 Shl Group Ab inalador de gotículas líquidas medidas
CN102596987B (zh) 2009-10-30 2014-06-25 埃克斯利亚制药有限公司 用于纯化粘菌素的方法和纯化的粘菌素组分
WO2012168820A1 (en) 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
CN102531955B (zh) 2011-09-16 2014-02-19 浙江众益制药股份有限公司 奥沙拉秦钠的制备方法和甲磺化反应的后处理方法
CA2895910C (en) 2013-01-11 2021-12-21 Xellia Pharmaceuticals Aps Polymyxins, compositions, methods of making and methods of use
TW201522364A (zh) 2013-06-07 2015-06-16 Xellia Pharmaceuticals Aps 黏菌素甲磺酸鈉（ｃｍｓ）之定性方法
PT3166960T (pt) 2014-07-09 2019-10-25 Xellia Pharmaceuticals Aps Polimixinas de baixa substituição e composições das mesmas.
CN106794221B (zh) 2014-10-03 2021-12-10 埃克斯利亚制药有限公司 组合物

Also Published As

Publication number Publication date
CY1121803T1 (el) 2020-07-31
EP3200762B1 (en) 2019-03-27
KR102494511B1 (ko) 2023-01-31
RU2017114144A (ru) 2018-11-06
AU2015326847B2 (en) 2018-11-29
AU2015326847A1 (en) 2017-04-13
PH12017500538A1 (en) 2017-08-07
JP2017530138A (ja) 2017-10-12
CN106999542A (zh) 2017-08-01
SI3200762T1 (sl) 2019-08-30
EP3200762A1 (en) 2017-08-09
JP6626890B2 (ja) 2019-12-25
RS58792B1 (sr) 2019-07-31
CA2962120C (en) 2023-09-19
US20190022171A1 (en) 2019-01-24
RU2017114144A3 (es) 2019-04-17
TR201906108T4 (tr) 2019-05-21
MX2017004175A (es) 2017-08-28
IL251480A0 (en) 2017-05-29
RU2702335C2 (ru) 2019-10-08
WO2016050933A1 (en) 2016-04-07
HRP20190747T1 (hr) 2019-07-12
PT3200762T (pt) 2019-05-28
PL3200762T3 (pl) 2019-08-30
EP3520777B1 (en) 2020-09-30
HUE044289T2 (hu) 2019-10-28
IL251480B (en) 2019-09-26
LT3200762T (lt) 2019-06-10
CN106999542B (zh) 2021-02-02
KR20170062521A (ko) 2017-06-07
SG11201702666SA (en) 2017-04-27
BR112017006816A2 (pt) 2018-01-09
DK3200762T3 (da) 2019-05-06
EP3520777A1 (en) 2019-08-07
CA2962120A1 (en) 2016-04-07
US11033602B2 (en) 2021-06-15
SMT201900275T1 (it) 2019-07-11
CO2017004442A2 (es) 2017-09-29

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