ES274455A1 - Un procedimiento para preparar 5-(3'-dimetilamino-2'-metilpropil) dibenzo/a,d/1,4/ -cicloheptadieno y sus sales farmacologicamente aceptables - Google Patents

Un procedimiento para preparar 5-(3'-dimetilamino-2'-metilpropil) dibenzo/a,d/1,4/ -cicloheptadieno y sus sales farmacologicamente aceptables

Info

Publication number: ES274455A1
Authority: ES; Spain
Prior art keywords: methyl; dimethylamino; optically active; propyl; dibenzo
Prior art date: 1961-02-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0274455A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth Canada Inc

Original Assignee

Ayerst Mckenna and Harrison Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1961-02-10

Filing date

1962-02-09

Publication date

1962-07-01

1962-02-09 Application filed by Ayerst Mckenna and Harrison Inc filed Critical Ayerst Mckenna and Harrison Inc

1962-07-01 Publication of ES274455A1 publication Critical patent/ES274455A1/es

Status Expired legal-status Critical Current

Links

QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
-1 3-Dimethylamino -2- methyl propyl halide Chemical class 0.000 abstract 1
UGXACBBAXFABGT-UHFFFAOYSA-N 3-chloro-n,n,2-trimethylpropan-1-amine Chemical compound ClCC(C)CN(C)C UGXACBBAXFABGT-UHFFFAOYSA-N 0.000 abstract 1
239000007818 Grignard reagent Substances 0.000 abstract 1
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical group [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
MIOPJNTWMNEORI-UHFFFAOYSA-N camphorsulfonic acid Chemical compound C1CC2(CS(O)(=O)=O)C(=O)CC1C2(C)C MIOPJNTWMNEORI-UHFFFAOYSA-N 0.000 abstract 1
239000003638 chemical reducing agent Substances 0.000 abstract 1
PJQCANLCUDUPRF-UHFFFAOYSA-N dibenzocycloheptene Chemical compound C1CC2=CC=CC=C2CC2=CC=CC=C12 PJQCANLCUDUPRF-UHFFFAOYSA-N 0.000 abstract 1
150000004795 grignard reagents Chemical class 0.000 abstract 1
OGQVROWWFUXRST-UHFFFAOYSA-N heptadiene group Chemical class C=CC=CCCC OGQVROWWFUXRST-UHFFFAOYSA-N 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
235000002906 tartaric acid Nutrition 0.000 abstract 1
239000011975 tartaric acid Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES0274455A 1961-02-10 1962-02-09 Un procedimiento para preparar 5-(3'-dimetilamino-2'-metilpropil) dibenzo/a,d/1,4/ -cicloheptadieno y sus sales farmacologicamente aceptables Expired ES274455A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CA816737		1961-02-10
US13410561A	1961-08-28	1961-08-28

Publications (1)

Publication Number	Publication Date
ES274455A1 true ES274455A1 (es)	1962-07-01

Family

ID=25673352

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0274455A Expired ES274455A1 (es)	1961-02-10	1962-02-09	Un procedimiento para preparar 5-(3'-dimetilamino-2'-metilpropil) dibenzo/a,d/1,4/ -cicloheptadieno y sus sales farmacologicamente aceptables

Country Status (3)

Country	Link
ES (1)	ES274455A1 (fr)
FR (1)	FR2133M (fr)
GB (1)	GB975465A (fr)

1962
- 1962-02-06 GB GB4544/62A patent/GB975465A/en not_active Expired
- 1962-02-09 ES ES0274455A patent/ES274455A1/es not_active Expired
- 1962-05-08 FR FR896808A patent/FR2133M/fr active Active

Also Published As

Publication number	Publication date
GB975465A (en)	1964-11-18
FR2133M (fr)	1963-11-12

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