ES281304A1 - Un procedimiento para la preparación de nuevos polipéptidos hipotensores - Google Patents

Un procedimiento para la preparación de nuevos polipéptidos hipotensores

Info

Publication number: ES281304A1
Authority: ES; Spain
Prior art keywords: methioninamide; phenylalanyl; leucyl; alanyl; glycyl
Prior art date: 1961-10-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES281304A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Italia SRL

Original Assignee

Farmaceutici Italia SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1961-10-05

Filing date

1962-10-04

Publication date

1963-04-16

1962-10-04 Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA

1963-04-16 Publication of ES281304A1 publication Critical patent/ES281304A1/es

Status Expired legal-status Critical Current

Links

208000001953 Hypotension Diseases 0.000 title abstract 2
208000021822 hypotensive Diseases 0.000 title abstract 2
230000001077 hypotensive effect Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
229920001184 polypeptide Polymers 0.000 title abstract 2
102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
125000006239 protecting group Chemical group 0.000 abstract 4
125000003277 amino group Chemical group 0.000 abstract 3
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
XRGQYRDWHWWDOP-JEUDFCHESA-N (3s)-3-amino-4-[[(2s)-1-[[(2s)-1-[[(2s,3s)-1-[[2-[[(2s)-1-[[(2s)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4 Chemical compound CSCC[C@@H](C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)CC1=CC=CC=C1 XRGQYRDWHWWDOP-JEUDFCHESA-N 0.000 abstract 1
RUXQNKVQSKOOBS-JURCDPSOSA-N Ala-Phe-Ile Chemical compound [H]N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(O)=O RUXQNKVQSKOOBS-JURCDPSOSA-N 0.000 abstract 1
KPNWAJMEMRCLAL-GUBZILKMSA-N Gln-Ser-Lys Chemical compound C(CCN)C[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N)N KPNWAJMEMRCLAL-GUBZILKMSA-N 0.000 abstract 1
RLXSTJVYBMNHEP-UWVGGRQHSA-N Gly-L-Leu-L-Met-NH2 Chemical compound CSCC[C@@H](C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CN RLXSTJVYBMNHEP-UWVGGRQHSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
229910021529 ammonia Inorganic materials 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ES281304A 1961-10-05 1962-10-04 Un procedimiento para la preparación de nuevos polipéptidos hipotensores Expired ES281304A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1798361		1961-10-05
IT216162		1962-02-05

Publications (1)

Publication Number	Publication Date
ES281304A1 true ES281304A1 (es)	1963-04-16

Family

ID=26325222

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES281304A Expired ES281304A1 (es)	1961-10-05	1962-10-04	Un procedimiento para la preparación de nuevos polipéptidos hipotensores

Country Status (7)

Country	Link
CH (1)	CH429754A (es)
DE (1)	DE1518133B1 (es)
DK (2)	DK108976C (es)
ES (1)	ES281304A1 (es)
FR (1)	FR2822M (es)
GB (1)	GB984810A (es)
SE (1)	SE302617B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1545519B1 (en)	2002-08-19	2011-03-23	Pfizer Inc.	Combination therapy for hyperproliferative diseases
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
US7919506B2 (en)	2006-03-10	2011-04-05	Pfizer Inc.	Dibenzyl amine compounds and derivatives
US8383660B2 (en)	2006-03-10	2013-02-26	Pfizer Inc.	Dibenzyl amine compounds and derivatives
JP5498168B2 (ja)	2006-12-01	2014-05-21	ブリストル−マイヤーズスクイブカンパニー	アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
SG11201507496UA (en)	2013-04-17	2015-11-27	Pfizer	N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en)	2014-10-08	2016-04-14	Pfizer Inc.	Substituted amide compounds
US11248001B2 (en)	2019-01-18	2022-02-15	Astrazeneca Ab	PCSK9 inhibitors and methods of use thereof
CN121574104A (zh) *	2026-01-23	2026-02-27	天津卡普希科技有限公司	一种美容肽脯氨酰-脯氨酰-赖氨酸的制备方法、缩合剂和应用

1962
- 1962-10-01 GB GB37178/62A patent/GB984810A/en not_active Expired
- 1962-10-01 DE DE19621518133 patent/DE1518133B1/de active Pending
- 1962-10-02 CH CH1155562A patent/CH429754A/de unknown
- 1962-10-03 FR FR911147A patent/FR2822M/fr not_active Expired
- 1962-10-03 DK DK352664AA patent/DK108976C/da active
- 1962-10-03 DK DK428662AA patent/DK104307C/da active
- 1962-10-04 ES ES281304A patent/ES281304A1/es not_active Expired
- 1962-10-04 SE SE10643/62A patent/SE302617B/xx unknown

Also Published As

Publication number	Publication date
SE302617B (es)	1968-07-29
CH429754A (de)	1967-02-15
GB984810A (en)	1965-03-03
DK104307C (da)	1966-05-02
DK108976C (da)	1968-03-04
DE1518133B1 (de)	1970-08-20
FR2822M (fr)	1964-10-05

Publication	Publication Date	Title
ES467453A1 (es)	1978-10-16	Un procedimiento para la preparacion de hentriacontapepti- dos.
NO834340L (no)	1984-05-28	Nye polypeptider
KR830004223A (ko)	1983-07-09	싸이클 헥사펩티드 소마토스테틴 유사체의 제조방법
GB1109086A (en)	1968-04-10	Polypeptides
ES2060123T3 (es)	1994-11-16	Aminoacidos protegidos y procedimientos para su fabricacion.
GB984810A (en)	1965-03-03	Polypeptides
ES403973A1 (es)	1975-11-16	Un procedimiento para la preparacion de monapeptidos.
ES8605769A1 (es)	1985-12-16	Un procedimiento para la preparacion de un peptido
ES391701A1 (es)	1973-06-16	Un procedimiento para la preparacion de hepta y octapepti- dos.
ES471793A1 (es)	1979-02-01	Un procedimiento para preparar peptidos
ES402609A1 (es)	1975-04-16	Procedimiento para la recuperacion de d-penicilamina.
GB1278681A (en)	1972-06-21	Peptides
ES295653A1 (es)	1964-06-16	Un procedimiento para preparar una nueva clase de polipéptidos
ES418158A1 (es)	1976-08-01	Un procedimiento de preparacion de nuevos peptidos.
GB992957A (en)	1965-05-26	New decapeptides and their manufacture
ATE15209T1 (de)	1985-09-15	Verfahren zur herstellung von carbonsaeureamidgruppen enthaltenden verbindungen, insbesondere von peptiden.
GB1000718A (en)	1965-08-11	New hexapeptide
FR2090682A5 (en)	1972-01-14	Pyroglutamyl-histidyl-prolineamide as thyroid stimulant- - from prolineamide and tosyl -l-histidine derivs
ES8101541A1 (es)	1980-12-16	Un procedimiento para la preparacion de un peptido.
ES419803A1 (es)	1976-12-16	Un procedimiento para la preparacion de acidos 3-alquil-3- cefem-4-carboxilicos.
FR4219M (es)	1966-07-18
GB1164618A (en)	1969-09-17	Tetracosapeptides and Process for their Manufacture
GB1190077A (en)	1970-04-29	Peptides and Process for Preparing them
ES8502731A1 (es)	1985-01-16	Un procedimiento para la preparacion de un peptido ciclico a-21978c.
GB1037168A (en)	1966-07-27	A new peptide and production thereof