ES281304A1 - Un procedimiento para la preparación de nuevos polipéptidos hipotensores - Google Patents

Un procedimiento para la preparación de nuevos polipéptidos hipotensores

Info

Publication number: ES281304A1
Authority: ES; Spain
Prior art keywords: methioninamide; phenylalanyl; leucyl; alanyl; glycyl
Prior art date: 1961-10-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES281304A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Italia SRL

Original Assignee

Farmaceutici Italia SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1961-10-05

Filing date

1962-10-04

Publication date

1963-04-16

1962-10-04 Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA

1963-04-16 Publication of ES281304A1 publication Critical patent/ES281304A1/es

Status Expired legal-status Critical Current

Links

208000001953 Hypotension Diseases 0.000 title abstract 2
208000021822 hypotensive Diseases 0.000 title abstract 2
230000001077 hypotensive effect Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
229920001184 polypeptide Polymers 0.000 title abstract 2
102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
125000006239 protecting group Chemical group 0.000 abstract 4
125000003277 amino group Chemical group 0.000 abstract 3
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
XRGQYRDWHWWDOP-JEUDFCHESA-N (3s)-3-amino-4-[[(2s)-1-[[(2s)-1-[[(2s,3s)-1-[[2-[[(2s)-1-[[(2s)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4 Chemical compound CSCC[C@@H](C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)CC1=CC=CC=C1 XRGQYRDWHWWDOP-JEUDFCHESA-N 0.000 abstract 1
RUXQNKVQSKOOBS-JURCDPSOSA-N Ala-Phe-Ile Chemical compound [H]N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(O)=O RUXQNKVQSKOOBS-JURCDPSOSA-N 0.000 abstract 1
KPNWAJMEMRCLAL-GUBZILKMSA-N Gln-Ser-Lys Chemical compound C(CCN)C[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)N)N KPNWAJMEMRCLAL-GUBZILKMSA-N 0.000 abstract 1
RLXSTJVYBMNHEP-UWVGGRQHSA-N Gly-L-Leu-L-Met-NH2 Chemical compound CSCC[C@@H](C(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CN RLXSTJVYBMNHEP-UWVGGRQHSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
229910021529 ammonia Inorganic materials 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ES281304A 1961-10-05 1962-10-04 Un procedimiento para la preparación de nuevos polipéptidos hipotensores Expired ES281304A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1798361		1961-10-05
IT216162		1962-02-05

Publications (1)

Publication Number	Publication Date
ES281304A1 true ES281304A1 (es)	1963-04-16

Family

ID=26325222

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES281304A Expired ES281304A1 (es)	1961-10-05	1962-10-04	Un procedimiento para la preparación de nuevos polipéptidos hipotensores

Country Status (7)

Country	Link
CH (1)	CH429754A (es)
DE (1)	DE1518133B1 (es)
DK (2)	DK104307C (es)
ES (1)	ES281304A1 (es)
FR (1)	FR2822M (es)
GB (1)	GB984810A (es)
SE (1)	SE302617B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2495962A1 (en)	2002-08-19	2004-03-04	Pfizer Products Inc.	Combination therapy for hyperproliferative diseases
US7741317B2 (en)	2005-10-21	2010-06-22	Bristol-Myers Squibb Company	LXR modulators
US7888376B2 (en)	2005-11-23	2011-02-15	Bristol-Myers Squibb Company	Heterocyclic CETP inhibitors
US8383660B2 (en)	2006-03-10	2013-02-26	Pfizer Inc.	Dibenzyl amine compounds and derivatives
US7919506B2 (en)	2006-03-10	2011-04-05	Pfizer Inc.	Dibenzyl amine compounds and derivatives
CN101663262B (zh)	2006-12-01	2014-03-26	百时美施贵宝公司	用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物
MX2015014666A (es)	2013-04-17	2016-03-01	Pfizer	Derivados de n-piperidin-3-ilbenzamida para tratar enfermedades cardiovasculares.
WO2016055901A1 (en)	2014-10-08	2016-04-14	Pfizer Inc.	Substituted amide compounds
SG11202107614PA (en)	2019-01-18	2021-08-30	Astrazeneca Ab	Pcsk9 inhibitors and methods of use thereof
CN121574104A (zh) *	2026-01-23	2026-02-27	天津卡普希科技有限公司	一种美容肽脯氨酰-脯氨酰-赖氨酸的制备方法、缩合剂和应用

1962
- 1962-10-01 GB GB37178/62A patent/GB984810A/en not_active Expired
- 1962-10-01 DE DE19621518133 patent/DE1518133B1/de active Pending
- 1962-10-02 CH CH1155562A patent/CH429754A/de unknown
- 1962-10-03 DK DK428662AA patent/DK104307C/da active
- 1962-10-03 FR FR911147A patent/FR2822M/fr not_active Expired
- 1962-10-03 DK DK352664AA patent/DK108976C/da active
- 1962-10-04 SE SE10643/62A patent/SE302617B/xx unknown
- 1962-10-04 ES ES281304A patent/ES281304A1/es not_active Expired

Also Published As

Publication number	Publication date
FR2822M (fr)	1964-10-05
DK104307C (da)	1966-05-02
GB984810A (en)	1965-03-03
DK108976C (da)	1968-03-04
CH429754A (de)	1967-02-15
DE1518133B1 (de)	1970-08-20
SE302617B (es)	1968-07-29

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