ES281347A1 - Procedure for the manufacture of basic derivatives of dibenzo [b. E] -oxepine or dibenzo- [b, e] -tiepine, from its salts and quaternary ammonium combinations (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the manufacture of basic derivatives of dibenzo [b. E] -oxepine or dibenzo- [b, e] -tiepine, from its salts and quaternary ammonium combinations (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Roche Diagnostics GmbH
CF Boehringer und Soehne GmbH
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Boehringer Mannheim GmbH
CF Boehringer und Soehne GmbH
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Application filed by Boehringer Mannheim GmbH, CF Boehringer und Soehne GmbHfiledCriticalBoehringer Mannheim GmbH
Publication of ES281347A1publicationCriticalpatent/ES281347A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Process for the manufacture of dibenzo- [b, e] -oxepine or dibenzo- [b, e] -thiepine derivatives of their salts and quaternary ammonium combinations, characterized in that from the general formula I ** (See formula) ** wherein X means an oxygen or sulfur atom, R1 and R2 hydrogen, halogen, trifluoromethyl, alkyl, alkoxy, alkylmercapto or acyl residues, R3 hydrogen or a lower alkyl radical and A a basic group, and its quaternary ammonium salts and combinations, to the dibenzo- [b, e] -oxepin or tiepin-ll-omas, of the formula II ** (See formula) ** where X, R1 and R2 have the above meaning, they are reacted with Grignard combinations of the formula (see formula), in which R3 and A have the meaning indicated at the beginning, and the product of the reaction is treated with water-dissociating media, after which the obtained alkylidene (I) combinations are transferred it interests its salts or quaternary ammonium combinations. (Machine-translation by Google Translate, not legally binding)
ES0281347A1961-10-071962-10-06Procedure for the manufacture of basic derivatives of dibenzo [b. E] -oxepine or dibenzo- [b, e] -tiepine, from its salts and quaternary ammonium combinations (Machine-translation by Google Translate, not legally binding)
ExpiredES281347A1
(en)
Procedure for the manufacture of basic derivatives of dibenzo [b. E] -oxepine or dibenzo- [b, e] -tiepine, from its salts and quaternary ammonium combinations (Machine-translation by Google Translate, not legally binding)
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Procedure for the manufacture of basic derivatives of dibenzo [b. E] -oxepine or dibenzo- [b, e] -tiepine, from its salts and quaternary ammonium combinations (Machine-translation by Google Translate, not legally binding)
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