ES284046A1 - Un procedimiento para la preparación de una nueva clase de derivados de la 6-metil y 1,6-dimetil-ergolina i - Google Patents

Un procedimiento para la preparación de una nueva clase de derivados de la 6-metil y 1,6-dimetil-ergolina i

Info

Publication number: ES284046A1
Authority: ES; Spain
Prior art keywords: methyl; ergoline; dimethyl; translation; derivatives
Prior art date: 1962-01-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES284046A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Italia SRL

Original Assignee

Farmaceutici Italia SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1962-01-11

Filing date

1963-01-10

Publication date

1963-07-01

1963-01-10 Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA

1963-07-01 Publication of ES284046A1 publication Critical patent/ES284046A1/es

Status Expired legal-status Critical Current

Links

UNELDXFWWQRODL-IUODEOHRSA-N (6ar,10ar)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline Chemical compound C1=CC([C@H]2CCCN([C@@H]2C2)C)=C3C2=CN(C)C3=C1 UNELDXFWWQRODL-IUODEOHRSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
-1 cycloaliphatic Chemical group 0.000 abstract 4
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
125000001931 aliphatic group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000000623 heterocyclic group Chemical group 0.000 abstract 2
150000002923 oximes Chemical class 0.000 abstract 2
GNLJBJNONOOOQC-UHFFFAOYSA-N $l^{3}-carbane;magnesium Chemical compound [Mg]C GNLJBJNONOOOQC-UHFFFAOYSA-N 0.000 abstract 1
DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 1
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
238000003747 Grignard reaction Methods 0.000 abstract 1
AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
TVLOHELFBBHWQM-IYMXMJTCSA-N NC(CC)C1CN[C@@H]2CC3=CNC4=CC=CC([C@H]2C1)=C34 Chemical compound NC(CC)C1CN[C@@H]2CC3=CNC4=CC=CC([C@H]2C1)=C34 TVLOHELFBBHWQM-IYMXMJTCSA-N 0.000 abstract 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
CDKFWIMBZAUBRS-UHFFFAOYSA-M [I-].CC[Mg+] Chemical compound [I-].CC[Mg+] CDKFWIMBZAUBRS-UHFFFAOYSA-M 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
150000004791 alkyl magnesium halides Chemical class 0.000 abstract 1
150000008064 anhydrides Chemical class 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
238000004587 chromatography analysis Methods 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
239000011591 potassium Substances 0.000 abstract 1
229910052700 potassium Inorganic materials 0.000 abstract 1
239000011734 sodium Substances 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
150000003512 tertiary amines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES284046A 1962-01-11 1963-01-10 Un procedimiento para la preparación de una nueva clase de derivados de la 6-metil y 1,6-dimetil-ergolina i Expired ES284046A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT46362		1962-01-11

Publications (1)

Publication Number	Publication Date
ES284046A1 true ES284046A1 (es)	1963-07-01

Family

ID=11098737

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES284046A Expired ES284046A1 (es)	1962-01-11	1963-01-10	Un procedimiento para la preparación de una nueva clase de derivados de la 6-metil y 1,6-dimetil-ergolina i

Country Status (6)

Country	Link
AT (1)	AT253685B (de)
CH (1)	CH445507A (de)
DK (1)	DK105034C (de)
ES (1)	ES284046A1 (de)
GB (1)	GB969147A (de)
SE (1)	SE309245B (de)

1963
- 1963-01-07 GB GB744/63A patent/GB969147A/en not_active Expired
- 1963-01-07 AT AT11363A patent/AT253685B/de active
- 1963-01-08 CH CH17463A patent/CH445507A/de unknown
- 1963-01-09 SE SE211/63A patent/SE309245B/xx unknown
- 1963-01-10 ES ES284046A patent/ES284046A1/es not_active Expired
- 1963-01-10 DK DK10363AA patent/DK105034C/da active

Also Published As

Publication number	Publication date
SE309245B (de)	1969-03-17
AT253685B (de)	1967-04-25
CH445507A (de)	1967-10-31
DK105034C (da)	1966-08-08
GB969147A (en)	1964-09-09

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