ES286482A1 - Un procedimiento mejorado para la producción de ácido 7-aminocefalosporánico - Google Patents

Un procedimiento mejorado para la producción de ácido 7-aminocefalosporánico

Info

Publication number: ES286482A1
Authority: ES; Spain
Prior art keywords: translation; production; machine; legally binding; google translate
Prior art date: 1962-03-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES286482A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Glaxo Laboratories Ltd

Original Assignee

Glaxo Laboratories Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1962-03-28

Filing date

1963-03-27

Publication date

1963-10-16

1963-03-27 Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd

1963-10-16 Publication of ES286482A1 publication Critical patent/ES286482A1/es

Status Expired legal-status Critical Current

Links

HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
HOKIDJSKDBPKTQ-GLXFQSAKSA-N Cephalosporin C Natural products S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 2
HOKIDJSKDBPKTQ-GLXFQSAKSA-M cephalosporin C(1-) Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H]([NH3+])C([O-])=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-M 0.000 abstract 2
BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
239000004157 Nitrosyl chloride Substances 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
235000019253 formic acid Nutrition 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000003701 inert diluent Substances 0.000 abstract 1
239000012046 mixed solvent Substances 0.000 abstract 1
VPCDQGACGWYTMC-UHFFFAOYSA-N nitrosyl chloride Chemical compound ClN=O VPCDQGACGWYTMC-UHFFFAOYSA-N 0.000 abstract 1
235000019392 nitrosyl chloride Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)

ES286482A 1962-03-28 1963-03-27 Un procedimiento mejorado para la producción de ácido 7-aminocefalosporánico Expired ES286482A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB11874/62A GB1017534A (en)	1962-03-28	1962-03-28	Improvements in or relating to the production of 7-aminocephalosporanic acid

Publications (1)

Publication Number	Publication Date
ES286482A1 true ES286482A1 (es)	1963-10-16

Family

ID=9994261

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES286482A Expired ES286482A1 (es)	1962-03-28	1963-03-27	Un procedimiento mejorado para la producción de ácido 7-aminocefalosporánico

Country Status (7)

Country	Link
US (1)	US3367933A (es)
AT (2)	AT249858B (es)
BR (1)	BR6348026D0 (es)
CH (1)	CH451157A (es)
ES (1)	ES286482A1 (es)
GB (1)	GB1017534A (es)
SE (2)	SE320071B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3507862A (en) *	1968-12-26	1970-04-21	Lilly Co Eli	Cleavage of cephalosporin c
US6518420B2 (en) *	1997-06-04	2003-02-11	Biochemie Gesellschaft M.B.H.	Precipitation process of 7-aminocephalosporanic acid (7-ACA)
KR20040014498A (ko) *	2001-04-19	2004-02-14	바이오퍼마 무르시아, 에스.에이.	세팔로스포린 유도체의 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3188311A (en) *	1961-04-03	1965-06-08	Lilly Co Eli	Process for the preparation of 7-amino-cephalosporanic acids

1962
- 1962-03-28 GB GB11874/62A patent/GB1017534A/en not_active Expired
1963
- 1963-03-26 CH CH379563A patent/CH451157A/de unknown
- 1963-03-27 SE SE3335/63A patent/SE320071B/xx unknown
- 1963-03-27 ES ES286482A patent/ES286482A1/es not_active Expired
- 1963-03-28 BR BR148026/63A patent/BR6348026D0/pt unknown
- 1963-03-28 AT AT250963A patent/AT249858B/de active
- 1963-03-28 AT AT243265A patent/AT249869B/de active
1965
- 1965-05-21 SE SE06659/65A patent/SE327991B/xx unknown
1966
- 1966-07-19 US US566387A patent/US3367933A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
BR6348026D0 (pt)	1973-07-03
CH451157A (de)	1968-05-15
AT249869B (de)	1966-10-10
US3367933A (en)	1968-02-06
GB1017534A (en)	1966-01-19
AT249858B (de)	1966-10-10
SE327991B (es)	1970-09-07
SE320071B (es)	1970-02-02

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