ES291377A1 - A method of preparing n-(d-1,6-dimethylisoergolenyl-8)-n,n-dialkylureas - Google Patents
A method of preparing n-(d-1,6-dimethylisoergolenyl-8)-n,n-dialkylureasInfo
- Publication number
- ES291377A1 ES291377A1 ES0291377A ES291377A ES291377A1 ES 291377 A1 ES291377 A1 ES 291377A1 ES 0291377 A ES0291377 A ES 0291377A ES 291377 A ES291377 A ES 291377A ES 291377 A1 ES291377 A1 ES 291377A1
- Authority
- ES
- Spain
- Prior art keywords
- dimethylisoergolenyl
- dialkylureas
- preparing
- compounds
- serotonine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002253 acid Chemical group 0.000 abstract 1
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of formula <FORM:1023795/C2/1> wherein R is a dimethylamino or diethylamino group, acid addition salts thereof, and their preparation by 1-methylation of the corresponding 1-unsubstituted compounds. The compounds of the invention have anti-serotonine activity. Reference has been directed by the Comptroller to Specification 950,528.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS512862 | 1962-09-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES291377A1 true ES291377A1 (en) | 1964-01-01 |
Family
ID=5395556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0291377A Expired ES291377A1 (en) | 1962-09-05 | 1963-09-04 | A method of preparing n-(d-1,6-dimethylisoergolenyl-8)-n,n-dialkylureas |
Country Status (4)
| Country | Link |
|---|---|
| AT (1) | AT240534B (en) |
| CH (1) | CH430738A (en) |
| ES (1) | ES291377A1 (en) |
| GB (1) | GB1023795A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0021206B1 (en) * | 1979-06-13 | 1983-06-22 | Schering Aktiengesellschaft | (ergolin-yl)-n', n'-diethyl urea derivatives, their preparation and pharmaceutical compositions containing them |
-
1963
- 1963-09-03 CH CH1086463A patent/CH430738A/en unknown
- 1963-09-04 AT AT712763A patent/AT240534B/en active
- 1963-09-04 ES ES0291377A patent/ES291377A1/en not_active Expired
- 1963-09-05 GB GB35040/63A patent/GB1023795A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH430738A (en) | 1967-02-28 |
| AT240534B (en) | 1965-06-10 |
| GB1023795A (en) | 1966-03-23 |
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