ES2927760T8 - Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas - Google Patents
Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativasInfo
- Publication number
- ES2927760T8 ES2927760T8 ES19164672T ES19164672T ES2927760T8 ES 2927760 T8 ES2927760 T8 ES 2927760T8 ES 19164672 T ES19164672 T ES 19164672T ES 19164672 T ES19164672 T ES 19164672T ES 2927760 T8 ES2927760 T8 ES 2927760T8
- Authority
- ES
- Spain
- Prior art keywords
- cyclopropanated
- treatment
- fatty acids
- unsaturated fatty
- neurodegenerative diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000002148 esters Chemical class 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 title 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
- C07C69/635—Halogen-containing esters of saturated acids containing rings in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361892727P | 2013-10-18 | 2013-10-18 | |
| US201361896735P | 2013-10-29 | 2013-10-29 | |
| US201461925449P | 2014-01-09 | 2014-01-09 | |
| US201461925441P | 2014-01-09 | 2014-01-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2927760T3 ES2927760T3 (es) | 2022-11-10 |
| ES2927760T8 true ES2927760T8 (es) | 2023-05-05 |
Family
ID=51846995
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19164672T Active ES2927760T3 (es) | 2013-10-18 | 2014-10-20 | Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas |
| ES14793391T Active ES2732153T3 (es) | 2013-10-18 | 2014-10-20 | Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14793391T Active ES2732153T3 (es) | 2013-10-18 | 2014-10-20 | Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9962357B2 (es) |
| EP (3) | EP3567025B8 (es) |
| JP (1) | JP2016535012A (es) |
| CA (1) | CA2927675A1 (es) |
| DK (1) | DK3057934T3 (es) |
| ES (2) | ES2927760T3 (es) |
| PL (1) | PL3057934T3 (es) |
| PT (1) | PT3057934T (es) |
| WO (1) | WO2015058191A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180311209A1 (en) * | 2015-10-08 | 2018-11-01 | Cognitive Research Enterprises, Inc. | Dosing regimens of pkc activators |
| US20220133687A1 (en) * | 2020-11-02 | 2022-05-05 | Synaptogenix, Inc. | Methods of treating and preventing neurodegenerative diseases with hgf activating compounds |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY118354A (en) * | 1995-05-01 | 2004-10-30 | Scarista Ltd | 1,3-propane diol derivatives as bioactive compounds |
| JPH10139735A (ja) * | 1996-09-13 | 1998-05-26 | Sumitomo Chem Co Ltd | エステル化合物、それを有効成分とする有害生物防除剤およびその製造中間体 |
| WO2001062740A1 (en) * | 2000-02-25 | 2001-08-30 | South Alabama Medical Science Foundation | Mibefradil analogues and their use |
| JP4995423B2 (ja) | 2002-12-03 | 2012-08-08 | ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート | 物質を血液−脳関門を渡って輸送するための人工低密度リポタンパク質キャリア |
| US7521447B2 (en) * | 2003-03-03 | 2009-04-21 | Array Biopharma Inc. | P38 inhibitors and methods of use thereof |
| DE10351087A1 (de) * | 2003-10-31 | 2005-05-25 | Bayer Technology Services Gmbh | Feste Wirkstoff-Formulierung |
| CN101223884B (zh) * | 2007-01-15 | 2011-07-13 | 大日本除虫菊株式会社 | 杀虫防虫剂或害虫的摄食阻碍剂 |
| CA2731171C (en) | 2008-07-28 | 2016-10-18 | Blanchette Rockefeller Neurosciences Institute | Pkc-activating compounds for the treatment of neurodegenerative diseases |
| CN101608402B (zh) * | 2009-07-14 | 2011-07-27 | 东华大学 | 植物油改性含氟拒水整理剂、制备方法及其应用 |
| US10052299B2 (en) * | 2009-10-30 | 2018-08-21 | Retrotope, Inc. | Alleviating oxidative stress disorders with PUFA derivatives |
| WO2012137225A1 (en) * | 2011-04-08 | 2012-10-11 | Sphaera Pharma Pvt. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
| WO2012148891A1 (en) * | 2011-04-29 | 2012-11-01 | Evonik Degussa Corporation | Peptide-lipid conjugates and uses thereof |
| EP2780316B1 (en) | 2011-11-13 | 2020-04-15 | Blanchette Rockefeller Neurosciences Institute | Esters of dcpla and methods of treatment using the same |
-
2014
- 2014-10-20 US US15/028,487 patent/US9962357B2/en active Active
- 2014-10-20 WO PCT/US2014/061368 patent/WO2015058191A1/en not_active Ceased
- 2014-10-20 EP EP19164672.8A patent/EP3567025B8/en active Active
- 2014-10-20 DK DK14793391.5T patent/DK3057934T3/da active
- 2014-10-20 EP EP14793391.5A patent/EP3057934B1/en active Active
- 2014-10-20 CA CA2927675A patent/CA2927675A1/en not_active Abandoned
- 2014-10-20 PT PT14793391T patent/PT3057934T/pt unknown
- 2014-10-20 ES ES19164672T patent/ES2927760T3/es active Active
- 2014-10-20 ES ES14793391T patent/ES2732153T3/es active Active
- 2014-10-20 PL PL14793391T patent/PL3057934T3/pl unknown
- 2014-10-20 EP EP22184036.6A patent/EP4101835A1/en active Pending
- 2014-10-20 JP JP2016524133A patent/JP2016535012A/ja active Pending
-
2018
- 2018-04-04 US US15/945,041 patent/US20180325856A1/en not_active Abandoned
-
2019
- 2019-01-25 US US16/257,988 patent/US11273139B2/en not_active Expired - Fee Related
-
2022
- 2022-02-04 US US17/665,033 patent/US12016837B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9962357B2 (en) | 2018-05-08 |
| ES2927760T3 (es) | 2022-11-10 |
| WO2015058191A1 (en) | 2015-04-23 |
| US12016837B2 (en) | 2024-06-25 |
| ES2732153T3 (es) | 2019-11-20 |
| EP4101835A1 (en) | 2022-12-14 |
| CA2927675A1 (en) | 2015-04-23 |
| EP3567025B8 (en) | 2023-01-25 |
| US20160256427A1 (en) | 2016-09-08 |
| US20180325856A1 (en) | 2018-11-15 |
| EP3057934A1 (en) | 2016-08-24 |
| US20190192471A1 (en) | 2019-06-27 |
| PL3057934T3 (pl) | 2019-09-30 |
| EP3567025B1 (en) | 2022-08-03 |
| EP3057934B1 (en) | 2019-03-27 |
| DK3057934T3 (da) | 2019-07-01 |
| JP2016535012A (ja) | 2016-11-10 |
| US11273139B2 (en) | 2022-03-15 |
| EP3567025A1 (en) | 2019-11-13 |
| US20220151973A1 (en) | 2022-05-19 |
| PT3057934T (pt) | 2019-06-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUE046239T2 (hu) | Zsírsav keverékek gyulladásos megbetegedések kezelésében való alkalmazásra | |
| CO6910186A2 (es) | Uso de ácidos grasos omega para el tratamiento de enfermedades | |
| IL243481A0 (en) | Drug for treatment of nonalcoholic fatty liver disease | |
| PL2717692T3 (pl) | Kwasy tetrahydrokannabinol-11-owe do stosowania w leczeniu chorób zwłóknieniowych | |
| PT2872497T (pt) | Derivados de cromanilo para o tratamento de doenças mitocondriais | |
| ZA201702385B (en) | Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states | |
| HUE050205T2 (hu) | Omega-3 zsírsavak készítményei az idegrendszer károsodásával járó betegségek kezelésére | |
| IL250271A0 (en) | A mixture of fatty acids and palmitoylethanolamide for use in the treatment of inflammatory and allergic pathologies | |
| EP2941252A4 (en) | USE OF FATTY ACID NIACIN CONJUGATES FOR THE TREATMENT OF DISEASES | |
| CL2014001883A1 (es) | Compuestos y métodos para el tratamiento de las infecciones de candidiasis y aspergillus | |
| ZA201603117B (en) | Withanolides useful for the treatment of neurodegenerative diseases | |
| PT3016654T (pt) | Ácido tauroursodeoxicólico (tudca) para utilização no tratamento de doenças neurodegenerativas | |
| PT3004353T (pt) | Bumetanida para tratar doenças neurodegenerativas com síndromes parkinsonianos | |
| GB201406390D0 (en) | The local treatment of inflammatory ophthalmic diseases | |
| SG11201507181YA (en) | Method for the treatment of fatty liver disease | |
| PL2810935T3 (pl) | Siarczanowane estry kwasów oligohydroksykarboksylowych i ich zastosowanie | |
| IL245199A (en) | Processes for making unsaturated esters | |
| ES2927760T8 (es) | Esteres halogenados de ácidos grasos insaturados ciclopropanados para su utilización en el tratamiento de las enfermedades neurodegenerativas | |
| CL2015001520A1 (es) | Proteina slurp-1 para usarse en el tratamiento de enfermedades oculares | |
| ES1136010Y (es) | Dispositivo de agua para prevenir la proliferacion de seres vivos en las conducciones de agua | |
| ES1136008Y (es) | Instalacion de agua para prevenir la proliferacion de seres vivos en las conducciones de agua | |
| HUE042691T2 (hu) | Tiazolo-pirimidinon felhasználása gyulladásos bélbetegségek kezeléséhez | |
| ES1087856Y (es) | Aposento para tratamiento terapeutico de animales | |
| HK1232769A1 (en) | Mixture of fatty acids and palmitoylethanolamide for use in the treatment of inflammatory and allergic pathologies | |
| TH1601000171A (th) | องค์ประกอบที่อีมัลซิฟายได้เองของ Omega3 แฟตตี้แอซิด |