ES2985191T3 - Detección de metilación de nucleótidos en ácidos nucleicos - Google Patents

Detección de metilación de nucleótidos en ácidos nucleicos Download PDF

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Publication number
ES2985191T3
ES2985191T3 ES20853612T ES20853612T ES2985191T3 ES 2985191 T3 ES2985191 T3 ES 2985191T3 ES 20853612 T ES20853612 T ES 20853612T ES 20853612 T ES20853612 T ES 20853612T ES 2985191 T3 ES2985191 T3 ES 2985191T3
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methylation
dna
sequencing
molecule
nucleic acid
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Spanish (es)
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Yuk-Ming Dennis Lo
Rossa Wai Kwun Chiu
Kwan Chee Chan
Peiyong Jiang
Suk Hang Cheng
Wenlei Peng
On Yee Tse
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Chinese University of Hong Kong CUHK
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Chinese University of Hong Kong CUHK
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    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6869—Methods for sequencing
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • C—CHEMISTRY; METALLURGY
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/164—Methylation detection other then bisulfite or methylation sensitive restriction endonucleases
    • C—CHEMISTRY; METALLURGY
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/601—Detection means characterised by use of a special device being a microscope, e.g. atomic force microscopy [AFM]
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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ES20853612T 2019-08-16 2020-08-17 Detección de metilación de nucleótidos en ácidos nucleicos Active ES2985191T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962887987P 2019-08-16 2019-08-16
US202062970586P 2020-02-05 2020-02-05
US202062991891P 2020-03-19 2020-03-19
US202063019790P 2020-05-04 2020-05-04
US202063051210P 2020-07-13 2020-07-13
PCT/CN2020/109602 WO2021032060A1 (en) 2019-08-16 2020-08-17 Determination of base modifications of nucleic acids

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ES2985191T3 true ES2985191T3 (es) 2024-11-04

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ES20853612T Active ES2985191T3 (es) 2019-08-16 2020-08-17 Detección de metilación de nucleótidos en ácidos nucleicos
ES24151720T Active ES3003866T3 (en) 2019-08-16 2020-08-17 Detection of methylation of a cytosine of nucleic acids

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ES24151720T Active ES3003866T3 (en) 2019-08-16 2020-08-17 Detection of methylation of a cytosine of nucleic acids

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US (4) US11091794B2 (he)
EP (3) EP3827092B1 (he)
JP (4) JP7264534B2 (he)
KR (4) KR102427319B1 (he)
CN (5) CN112752853B (he)
AU (4) AU2020323958B2 (he)
BR (1) BR122021009560B1 (he)
CA (1) CA3110884A1 (he)
DK (2) DK3827092T3 (he)
ES (2) ES2985191T3 (he)
GB (13) GB2619466B (he)
IL (3) IL302199B2 (he)
MX (3) MX389993B (he)
NZ (4) NZ786185A (he)
PH (1) PH12021550223A1 (he)
SG (1) SG11202101070QA (he)
TW (5) TWI752593B (he)
WO (1) WO2021032060A1 (he)
ZA (1) ZA202100887B (he)

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AU2023210593B2 (en) 2024-03-21
KR20220109492A (ko) 2022-08-04
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GB202210633D0 (en) 2022-08-31
NZ796695A (en) 2024-02-23
GB2590573A (en) 2021-06-30
GB202103010D0 (en) 2021-04-14
GB2608713A (en) 2023-01-11
AU2022231719A1 (en) 2022-10-06
NZ786185A (en) 2022-08-26
CN112752853B (zh) 2023-06-30
PH12021550223A1 (en) 2021-10-11
EP4365307A3 (en) 2024-07-10
GB2615272A (en) 2023-08-02
GB2620069A (en) 2023-12-27
TWI832483B (zh) 2024-02-11
GB202201811D0 (en) 2022-03-30
GB2590573B (en) 2021-12-22
GB2620315A (en) 2024-01-03
MX2022001469A (es) 2022-02-22
WO2021032060A1 (en) 2021-02-25
TW202124728A (zh) 2021-07-01
TWI752593B (zh) 2022-01-11
KR20220109493A (ko) 2022-08-04
KR102658592B1 (ko) 2024-04-17
GB2609830A (en) 2023-02-15
IL294153B2 (he) 2023-09-01
US20210047679A1 (en) 2021-02-18
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