ES302607A1 - Procedimiento para la producciën de compuestos de pirrolidina - Google Patents
Procedimiento para la producciën de compuestos de pirrolidinaInfo
- Publication number
- ES302607A1 ES302607A1 ES0302607A ES302607A ES302607A1 ES 302607 A1 ES302607 A1 ES 302607A1 ES 0302607 A ES0302607 A ES 0302607A ES 302607 A ES302607 A ES 302607A ES 302607 A1 ES302607 A1 ES 302607A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- substituted
- carbon atoms
- prepared
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003235 pyrrolidines Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 238000010992 reflux Methods 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000007868 Raney catalyst Substances 0.000 abstract 1
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 1
- 229910000564 Raney nickel Inorganic materials 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- KXZJHVJKXJLBKO-UHFFFAOYSA-N chembl1408157 Chemical compound N=1C2=CC=CC=C2C(C(=O)O)=CC=1C1=CC=C(O)C=C1 KXZJHVJKXJLBKO-UHFFFAOYSA-N 0.000 abstract 1
- 229940114081 cinnamate Drugs 0.000 abstract 1
- 229910017052 cobalt Inorganic materials 0.000 abstract 1
- 239000010941 cobalt Substances 0.000 abstract 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 1
- ZIUSEGSNTOUIPT-UHFFFAOYSA-N ethyl 2-cyanoacetate Chemical compound CCOC(=O)CC#N ZIUSEGSNTOUIPT-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical class [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000001640 fractional crystallisation Methods 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- -1 m-substituted phenyl Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- NNFCIKHAZHQZJG-UHFFFAOYSA-N potassium cyanide Chemical compound [K+].N#[C-] NNFCIKHAZHQZJG-UHFFFAOYSA-N 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3064563A GB1012008A (en) | 1963-08-01 | 1963-08-01 | Process for the production of pyrrolidine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES302607A1 true ES302607A1 (es) | 1965-03-16 |
Family
ID=10310880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0302607A Expired ES302607A1 (es) | 1963-08-01 | 1964-12-15 | Procedimiento para la producciën de compuestos de pirrolidina |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT252231B (de) |
| BR (1) | BR6461271D0 (de) |
| CH (1) | CH429726A (de) |
| DE (1) | DE1272296B (de) |
| DK (1) | DK114900B (de) |
| ES (1) | ES302607A1 (de) |
| FR (1) | FR1605308A (de) |
| GB (1) | GB1012008A (de) |
| NL (1) | NL6408740A (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4426386A (en) * | 1979-12-05 | 1984-01-17 | Astra Lakemedel Aktiebolag | Substituted phenyl piperidines |
-
1963
- 1963-08-01 GB GB3064563A patent/GB1012008A/en not_active Expired
-
1964
- 1964-07-30 CH CH997464A patent/CH429726A/fr unknown
- 1964-07-30 DE DEP1272A patent/DE1272296B/de active Pending
- 1964-07-30 FR FR983621A patent/FR1605308A/fr not_active Expired
- 1964-07-30 AT AT655764A patent/AT252231B/de active
- 1964-07-30 BR BR16127164A patent/BR6461271D0/pt unknown
- 1964-07-30 NL NL6408740A patent/NL6408740A/xx unknown
- 1964-07-31 DK DK380564A patent/DK114900B/da unknown
- 1964-12-15 ES ES0302607A patent/ES302607A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT252231B (de) | 1967-02-10 |
| DE1272296B (de) | 1968-07-11 |
| GB1012008A (en) | 1965-12-01 |
| FR1605308A (en) | 1974-08-02 |
| DK114900B (da) | 1969-08-18 |
| NL6408740A (de) | 1965-02-02 |
| CH429726A (fr) | 1967-02-15 |
| BR6461271D0 (pt) | 1973-07-17 |
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