ES302968A1 - Un método de preparacion de compuestos de alfa- (dialquilamino) trifluorometilpropiofenona - Google Patents

Un método de preparacion de compuestos de alfa- (dialquilamino) trifluorometilpropiofenona

Info

Publication number: ES302968A1
Authority: ES; Spain
Prior art keywords: compounds; reaction; compositions; diethylamino; effected
Prior art date: 1963-08-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0302968A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Richardson Vicks Inc

Original Assignee

Richardson Merrell Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1963-08-08

Filing date

1964-08-08

Publication date

1965-01-16

1964-08-08 Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc

1965-01-16 Publication of ES302968A1 publication Critical patent/ES302968A1/es

Status Expired legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 title abstract 7
230000001225 therapeutic effect Effects 0.000 title abstract 2
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
PCLIMKBDDGJMGD-UHFFFAOYSA-N N-bromosuccinimide Chemical compound BrN1C(=O)CCC1=O PCLIMKBDDGJMGD-UHFFFAOYSA-N 0.000 abstract 2
JRNVZBWKYDBUCA-UHFFFAOYSA-N N-chlorosuccinimide Chemical compound ClN1C(=O)CCC1=O JRNVZBWKYDBUCA-UHFFFAOYSA-N 0.000 abstract 2
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Substances OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 2
125000005265 dialkylamine group Chemical group 0.000 abstract 2
230000002140 halogenating effect Effects 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
239000000047 product Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 2
-1 trifluoromethylphenyl magnesium halide Chemical class 0.000 abstract 2
SOZGHDCEWOLLHV-UHFFFAOYSA-N 2-(trifluoromethyl)benzonitrile Chemical compound FC(F)(F)C1=CC=CC=C1C#N SOZGHDCEWOLLHV-UHFFFAOYSA-N 0.000 abstract 1
FFSQUPZKCFPFEM-UHFFFAOYSA-N 3,3,3-trifluoro-2-methyl-1-phenylpropan-1-one Chemical compound FC(F)(F)C(C)C(=O)C1=CC=CC=C1 FFSQUPZKCFPFEM-UHFFFAOYSA-N 0.000 abstract 1
PXRKCOCTEMYUEG-UHFFFAOYSA-N 5-aminoisoindole-1,3-dione Chemical compound NC1=CC=C2C(=O)NC(=O)C2=C1 PXRKCOCTEMYUEG-UHFFFAOYSA-N 0.000 abstract 1
239000005711 Benzoic acid Substances 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
QHJYQWRLIBPDHL-UHFFFAOYSA-N Cl.CC(C(=O)C1=CC=CC=C1)C Chemical compound Cl.CC(C(=O)C1=CC=CC=C1)C QHJYQWRLIBPDHL-UHFFFAOYSA-N 0.000 abstract 1
CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 1
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
229940124332 anorexigenic agent Drugs 0.000 abstract 1
239000002830 appetite depressant Substances 0.000 abstract 1
235000010233 benzoic acid Nutrition 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
235000015872 dietary supplement Nutrition 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
150000003840 hydrochlorides Chemical class 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
150000004658 ketimines Chemical class 0.000 abstract 1
239000008141 laxative Substances 0.000 abstract 1
229940125722 laxative agent Drugs 0.000 abstract 1
239000007788 liquid Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
VBTQNRFWXBXZQR-UHFFFAOYSA-N n-bromoacetamide Chemical compound CC(=O)NBr VBTQNRFWXBXZQR-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
WYVAMUWZEOHJOQ-UHFFFAOYSA-N propionic anhydride Chemical compound CCC(=O)OC(=O)CC WYVAMUWZEOHJOQ-UHFFFAOYSA-N 0.000 abstract 1
229940125723 sedative agent Drugs 0.000 abstract 1
239000000932 sedative agent Substances 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
YBBRCQOCSYXUOC-UHFFFAOYSA-N sulfuryl dichloride Chemical compound ClS(Cl)(=O)=O YBBRCQOCSYXUOC-UHFFFAOYSA-N 0.000 abstract 1
239000001117 sulphuric acid Substances 0.000 abstract 1
239000000829 suppository Substances 0.000 abstract 1
239000011782 vitamin Substances 0.000 abstract 1
229940088594 vitamin Drugs 0.000 abstract 1
229930003231 vitamin Natural products 0.000 abstract 1
235000013343 vitamin Nutrition 0.000 abstract 1
150000003722 vitamin derivatives Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ES0302968A 1963-08-08 1964-08-08 Un método de preparacion de compuestos de alfa- (dialquilamino) trifluorometilpropiofenona Expired ES302968A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US30090963A	1963-08-08	1963-08-08

Publications (1)

Publication Number	Publication Date
ES302968A1 true ES302968A1 (es)	1965-01-16

Family

ID=23161116

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0302968A Expired ES302968A1 (es)	1963-08-08	1964-08-08	Un método de preparacion de compuestos de alfa- (dialquilamino) trifluorometilpropiofenona

Country Status (3)

Country	Link
ES (1)	ES302968A1 (fr)
FR (1)	FR3590M (fr)
GB (1)	GB1019128A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2430933A1 (fr) *	1978-07-13	1980-02-08	Synthelabo	Derives de propiophenone et leur application en therapeutique

1964
- 1964-08-07 GB GB32345/64A patent/GB1019128A/en not_active Expired
- 1964-08-07 FR FR984594A patent/FR3590M/fr active Active
- 1964-08-08 ES ES0302968A patent/ES302968A1/es not_active Expired

Also Published As

Publication number	Publication date
FR3590M (fr)	1965-10-04
GB1019128A (en)	1966-02-02

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