ES309304A2 - PROCEDURE FOR THE MANUFACTURE OF NEW DIPHENYL-AMINO-ALKYLAMINES AND THEIR SALTS - Google Patents

Abstract

Improvements introduced in the main patent 308,580 on procedure for the manufacture of new diphenyl-amino-alkylamines of the general formula IX ** (See formula) ** wherein n is equal to 2 or 3, it means hydrogen or a lower alkyl radical and R 2 and R 3 hydrogen, halogen or lower alkyl radicals, but where R 2 and R 3 must not be hydrogen at the same time, and their salts, characterized in that O well a) amines of the general formula II are reduced ** (See formula) ** wherein R1 and n have the above meaning, together with phenylpropanones of the general formula III ** (See formula) ** wherein R2 and R3 have the above meaning, or b) diphenylamine is reacted with a halogenide of formula IV ** (See formula) ** wherein R1, R2, R3 and n have the above meaning, optionally in the presence of hydrazide linking means, or c) amines of the general formula V are reacted ** (See formula) ** wherein R1, R2 and R3 have the above meaning, with a halogenide of the general formula VI ** (See formula) ** wherein n has the above meaning, possibly in the presence of hydrazide linking means, or d) amides of organic acid of the general formula VII or VIII are reduced ** (See formula) ** wherein R 1, R 2, R 3 and n have the above meaning, to the state of the corresponding amines, after which the compounds obtained - if R 1 signifies a hydrogen atom - are subsequently subsequently distilled, as usual, in nitrogen, or else - provided that R1 and R3 mean alkoxy or aralkoxy groups, they are converted as usual to the corresponding hydroxy compounds, and if desired they are transferred to their salts. (Machine-translation by Google Translate, not legally binding)