ES310959A1 - Procedimiento para la preparaciën de derivados del acido glicerretinico - Google Patents
Procedimiento para la preparaciën de derivados del acido glicerretinicoInfo
- Publication number
- ES310959A1 ES310959A1 ES0310959A ES310959A ES310959A1 ES 310959 A1 ES310959 A1 ES 310959A1 ES 0310959 A ES0310959 A ES 0310959A ES 310959 A ES310959 A ES 310959A ES 310959 A1 ES310959 A1 ES 310959A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- glycyrrhetinic acid
- preparation
- keto
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical class C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- WTDHULULXKLSOZ-UHFFFAOYSA-N Hydroxylamine hydrochloride Chemical compound Cl.ON WTDHULULXKLSOZ-UHFFFAOYSA-N 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- YYROPELSRYBVMQ-UHFFFAOYSA-N 4-toluenesulfonyl chloride Chemical compound CC1=CC=C(S(Cl)(=O)=O)C=C1 YYROPELSRYBVMQ-UHFFFAOYSA-N 0.000 abstract 1
- 238000006237 Beckmann rearrangement reaction Methods 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 150000003950 cyclic amides Chemical class 0.000 abstract 1
- 229960003720 enoxolone Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- LVWZTYCIRDMTEY-UHFFFAOYSA-N metamizole Chemical compound O=C1C(N(CS(O)(=O)=O)C)=C(C)N(C)N1C1=CC=CC=C1 LVWZTYCIRDMTEY-UHFFFAOYSA-N 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/48—Chrysenes; Hydrogenated chrysenes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB12273/64A GB1046413A (en) | 1964-03-24 | 1964-03-24 | New derivatives of glycyrrhetinic acid and process for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES310959A1 true ES310959A1 (es) | 1966-01-16 |
Family
ID=10001528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0310959A Expired ES310959A1 (es) | 1964-03-24 | 1965-03-24 | Procedimiento para la preparaciën de derivados del acido glicerretinico |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3311613A (es) |
| BR (1) | BR6568086D0 (es) |
| DE (1) | DE1227893B (es) |
| ES (1) | ES310959A1 (es) |
| FR (2) | FR1574652A (es) |
| GB (2) | GB1046849A (es) |
| SE (1) | SE308520B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1093908A (en) * | 1965-11-26 | 1967-12-06 | Biorex Laboratories Ltd | New derivatives of glycyrrhetinic acid |
| GB1144862A (en) * | 1967-04-11 | 1969-03-12 | Biorex Laboratories Ltd | New tetracyclic triketones |
| EP2627327A1 (en) * | 2010-08-10 | 2013-08-21 | onepharm Research & Development GmbH | Novel triterpene derivatives |
| CN102516350B (zh) * | 2011-11-10 | 2014-12-10 | 沈阳化工大学 | 一种具有抗肿瘤活性的甘草次酸修饰物及其制备方法 |
| DK3539974T5 (en) * | 2016-11-09 | 2024-05-27 | Univ Osaka | Method for modifying t cell population |
| ES3053332A1 (es) * | 2024-06-27 | 2026-01-21 | Univ Oviedo | Compuestos obtenibles por modificación química del ácido glicirretínico, preparaciones farmacéuticas y sus usos, y método para la preparación de los mismos |
-
1964
- 1964-03-24 GB GB48214/65A patent/GB1046849A/en not_active Expired
- 1964-03-24 GB GB12273/64A patent/GB1046413A/en not_active Expired
-
1965
- 1965-03-04 DE DEB80814A patent/DE1227893B/de active Pending
- 1965-03-16 US US440290A patent/US3311613A/en not_active Expired - Lifetime
- 1965-03-23 SE SE3735/65A patent/SE308520B/xx unknown
- 1965-03-24 BR BR168086/65A patent/BR6568086D0/pt unknown
- 1965-03-24 FR FR1574652D patent/FR1574652A/fr not_active Expired
- 1965-03-24 ES ES0310959A patent/ES310959A1/es not_active Expired
- 1965-06-23 FR FR21900A patent/FR4947M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6568086D0 (pt) | 1973-09-11 |
| GB1046413A (en) | 1966-10-26 |
| US3311613A (en) | 1967-03-28 |
| FR4947M (es) | 1967-03-28 |
| GB1046849A (en) | 1966-10-26 |
| SE308520B (es) | 1969-02-17 |
| FR1574652A (es) | 1969-07-18 |
| DE1227893B (de) | 1966-11-03 |
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