ES312185A1 - Procedimiento de preparacion de nuevas penicilinas y sales atoxicas de las mismas - Google Patents
Procedimiento de preparacion de nuevas penicilinas y sales atoxicas de las mismasInfo
- Publication number
- ES312185A1 ES312185A1 ES0312185A ES312185A ES312185A1 ES 312185 A1 ES312185 A1 ES 312185A1 ES 0312185 A ES0312185 A ES 0312185A ES 312185 A ES312185 A ES 312185A ES 312185 A1 ES312185 A1 ES 312185A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- acid
- aralkyl
- aryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930182555 Penicillin Natural products 0.000 title abstract 4
- 150000002960 penicillins Chemical class 0.000 title abstract 3
- -1 m - aminophenyl Chemical group 0.000 abstract 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000003277 amino group Chemical group 0.000 abstract 2
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 1
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 150000001555 benzenes Chemical class 0.000 abstract 1
- HSDAJNMJOMSNEV-UHFFFAOYSA-N benzyl chloroformate Chemical compound ClC(=O)OCC1=CC=CC=C1 HSDAJNMJOMSNEV-UHFFFAOYSA-N 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- UKJLNMAFNRKWGR-UHFFFAOYSA-N cyclohexatrienamine Chemical class NC1=CC=C=C[CH]1 UKJLNMAFNRKWGR-UHFFFAOYSA-N 0.000 abstract 1
- 125000001240 enamine group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB16799/64A GB1033257A (en) | 1964-04-23 | 1964-04-23 | Penicillins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES312185A1 true ES312185A1 (es) | 1965-08-16 |
Family
ID=10083873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0312185A Expired ES312185A1 (es) | 1964-04-23 | 1965-04-23 | Procedimiento de preparacion de nuevas penicilinas y sales atoxicas de las mismas |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT264711B (de) |
| BE (1) | BE662478A (de) |
| BR (1) | BR6568922D0 (de) |
| CH (1) | CH442311A (de) |
| DE (1) | DE1545586A1 (de) |
| ES (1) | ES312185A1 (de) |
| FR (1) | FR4394M (de) |
| GB (1) | GB1033257A (de) |
| NL (1) | NL6505163A (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1190897B (it) * | 1982-06-29 | 1988-02-24 | Opos Biochimica Srl | Procedimento per la preparazione dell'estere 1-etossicarbonilossietilico dell'acido 6-(d(-)-alfa aminoalfa fenilacetamido)-penicillanico |
-
1964
- 1964-04-23 GB GB16799/64A patent/GB1033257A/en not_active Expired
-
1965
- 1965-04-13 BR BR16892265A patent/BR6568922D0/pt unknown
- 1965-04-14 BE BE662478D patent/BE662478A/xx unknown
- 1965-04-16 FR FR13595A patent/FR4394M/fr not_active Expired
- 1965-04-21 CH CH553365A patent/CH442311A/de unknown
- 1965-04-21 DE DE19651545586 patent/DE1545586A1/de active Pending
- 1965-04-21 AT AT365565A patent/AT264711B/de active
- 1965-04-22 NL NL6505163A patent/NL6505163A/xx unknown
- 1965-04-23 ES ES0312185A patent/ES312185A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH442311A (de) | 1967-08-31 |
| AT264711B (de) | 1968-09-10 |
| BR6568922D0 (pt) | 1973-08-07 |
| NL6505163A (de) | 1965-10-25 |
| FR4394M (de) | 1966-09-05 |
| BE662478A (de) | 1965-10-14 |
| DE1545586A1 (de) | 1969-07-31 |
| GB1033257A (en) | 1966-06-22 |
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