ES313426A1 - Mejoras introducidas en la preparaciën de soluciones de insulina estables y farmaceuticamente aceptables - Google Patents

Mejoras introducidas en la preparaciën de soluciones de insulina estables y farmaceuticamente aceptables

Info

Publication number: ES313426A1
Authority: ES; Spain
Prior art keywords: insulin; stable; less; days; cell
Prior art date: 1964-05-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0313426A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wellcome Foundation Ltd

Original Assignee

Wellcome Foundation Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1964-05-26

Filing date

1965-05-26

Publication date

1966-02-16

1965-05-26 Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd

1966-02-16 Publication of ES313426A1 publication Critical patent/ES313426A1/es

Status Expired legal-status Critical Current

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 10
102000004877 Insulin Human genes 0.000 title abstract 5
108090001061 Insulin Proteins 0.000 title abstract 5
229940125396 insulin Drugs 0.000 title abstract 5
230000003287 optical effect Effects 0.000 abstract 2
239000000243 solution Substances 0.000 abstract 2
102000003670 Carboxypeptidase B Human genes 0.000 abstract 1
108090000087 Carboxypeptidase B Proteins 0.000 abstract 1
102000005237 Isophane Insulin Human genes 0.000 abstract 1
108010081368 Isophane Insulin Proteins 0.000 abstract 1
102000007327 Protamines Human genes 0.000 abstract 1
108010007568 Protamines Proteins 0.000 abstract 1
238000002835 absorbance Methods 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
235000015278 beef Nutrition 0.000 abstract 1
239000012470 diluted sample Substances 0.000 abstract 1
229940006445 isophane insulin Drugs 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
229940048914 protamine Drugs 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C07K14/625—Extraction from natural sources
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Fixed Capacitors And Capacitor Manufacturing Machines (AREA)

ES0313426A 1964-05-26 1965-05-26 Mejoras introducidas en la preparaciën de soluciones de insulina estables y farmaceuticamente aceptables Expired ES313426A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB21686/64A GB1106076A (en)	1964-05-26	1964-05-26	Stable, aqueous insulin solutions

Publications (1)

Publication Number	Publication Date
ES313426A1 true ES313426A1 (es)	1966-02-16

Family

ID=10167129

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0313426A Expired ES313426A1 (es)	1964-05-26	1965-05-26	Mejoras introducidas en la preparaciën de soluciones de insulina estables y farmaceuticamente aceptables

Country Status (16)

Country	Link
AT (1)	AT262502B (de)
BE (1)	BE664409A (de)
BR (1)	BR6569960D0 (de)
CH (1)	CH477882A (de)
DE (1)	DE1285674B (de)
DK (1)	DK111701B (de)
ES (1)	ES313426A1 (de)
FI (1)	FI44453B (de)
FR (2)	FR1587319A (de)
GB (1)	GB1106076A (de)
IL (1)	IL23611A (de)
LU (1)	LU48698A1 (de)
NL (1)	NL150683B (de)
NO (1)	NO118392B (de)
OA (1)	OA02001A (de)
SE (1)	SE360561B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20120241356A1 (en)	2009-07-06	2012-09-27	Sanofi-Aventis Deutschland Gmbh	Heat- and vibration-stable insulin preparations

1964
- 1964-05-26 GB GB21686/64A patent/GB1106076A/en not_active Expired
1965
- 1965-05-19 DE DEW39181A patent/DE1285674B/de active Pending
- 1965-05-24 BE BE664409A patent/BE664409A/xx unknown
- 1965-05-25 NO NO158255A patent/NO118392B/no unknown
- 1965-05-26 FI FI1265/65A patent/FI44453B/fi active
- 1965-05-26 ES ES0313426A patent/ES313426A1/es not_active Expired
- 1965-05-26 AT AT483165A patent/AT262502B/de active
- 1965-05-26 IL IL23611A patent/IL23611A/en unknown
- 1965-05-26 OA OA51910A patent/OA02001A/xx unknown
- 1965-05-26 LU LU48698D patent/LU48698A1/xx unknown
- 1965-05-26 FR FR1587319D patent/FR1587319A/fr not_active Expired
- 1965-05-26 DK DK268065AA patent/DK111701B/da unknown
- 1965-05-26 SE SE06947/65A patent/SE360561B/xx unknown
- 1965-05-26 NL NL656506714A patent/NL150683B/xx not_active IP Right Cessation
- 1965-05-26 BR BR169960/65A patent/BR6569960D0/pt unknown
- 1965-05-26 CH CH739865A patent/CH477882A/de not_active IP Right Cessation
- 1965-08-25 FR FR29358A patent/FR5038M/fr not_active Expired

Also Published As

Publication number	Publication date
OA02001A (fr)	1970-05-05
FI44453B (de)	1971-08-02
DE1285674B (de)	1968-12-19
BE664409A (de)	1965-11-24
AT262502B (de)	1968-06-10
NL6506714A (de)	1965-11-29
IL23611A (en)	1968-10-24
GB1106076A (en)	1968-03-13
NL150683B (nl)	1976-09-15
BR6569960D0 (pt)	1973-08-02
FR5038M (de)	1967-05-02
LU48698A1 (de)	1965-11-26
CH477882A (de)	1969-09-15
DK111701B (da)	1968-09-30
NO118392B (de)	1969-12-22
SE360561B (de)	1973-10-01
FR1587319A (de)	1970-03-20

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