ES315046A1 - Un procedimiento para la produccion de nuevos derivados de codeina y morfina - Google Patents

Un procedimiento para la produccion de nuevos derivados de codeina y morfina

Info

Publication number: ES315046A1
Authority: ES; Spain
Prior art keywords: group; compound; hydrogen atom; alkyl; general formula
Prior art date: 1964-07-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0315046A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Reckitt and Sons Ltd

Original Assignee

Reckitt and Sons Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1964-07-08

Filing date

1965-07-07

Publication date

1966-04-01

1965-07-07 Application filed by Reckitt and Sons Ltd filed Critical Reckitt and Sons Ltd

1966-04-01 Publication of ES315046A1 publication Critical patent/ES315046A1/es

Status Expired legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 abstract 10
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 10
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 6
125000000217 alkyl group Chemical group 0.000 abstract 6
125000004432 carbon atom Chemical group C* 0.000 abstract 6
125000003118 aryl group Chemical group 0.000 abstract 5
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 5
125000003342 alkenyl group Chemical group 0.000 abstract 3
-1 tetrahydroxy furanyl group Chemical group 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
125000002723 alicyclic group Chemical group 0.000 abstract 2
150000001350 alkyl halides Chemical class 0.000 abstract 2
FAMRKDQNMBBFBR-BQYQJAHWSA-N diethyl azodicarboxylate Chemical compound CCOC(=O)\N=N\C(=O)OCC FAMRKDQNMBBFBR-BQYQJAHWSA-N 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 2
BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
150000001266 acyl halides Chemical class 0.000 abstract 1
239000003513 alkali Substances 0.000 abstract 1
238000005904 alkaline hydrolysis reaction Methods 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
125000004429 atom Chemical group 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical class C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
150000004678 hydrides Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
125000000468 ketone group Chemical group 0.000 abstract 1
239000012280 lithium aluminium hydride Substances 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
229960005181 morphine Drugs 0.000 abstract 1
230000001590 oxidative effect Effects 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012279 sodium borohydride Substances 0.000 abstract 1
229910000033 sodium borohydride Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES0315046A 1964-07-08 1965-07-07 Un procedimiento para la produccion de nuevos derivados de codeina y morfina Expired ES315046A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB28156/64A GB1116595A (en)	1964-07-08	1964-07-08	Codeine and morphine derivatives

Publications (1)

Publication Number	Publication Date
ES315046A1 true ES315046A1 (es)	1966-04-01

Family

ID=31898259

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0315046A Expired ES315046A1 (es)	1964-07-08	1965-07-07	Un procedimiento para la produccion de nuevos derivados de codeina y morfina

Country Status (6)

Country	Link
US (1)	US3329682A (es)
BE (1)	BE666564A (es)
ES (1)	ES315046A1 (es)
FR (1)	FR5192M (es)
GB (1)	GB1116595A (es)
NL (1)	NL6508759A (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1136764A (en) *	1965-08-13	1968-12-18	Reckitt & Sons Ltd	Derivatives of thebaine and oripavine
GB1164671A (en) *	1967-03-31	1969-09-17	Reckitt & Sons Ltd	Novel Derivatives of Thebaine and Oripavine to their Salts, and to processes for their preparation
GB1164672A (en) *	1967-03-31	1969-09-17	Reckitt & Sons Ltd	Novel Derivatives of Thebaine and Oripavine, their Pharmaceutically Acceptable Salts, and to processes of their production
US3474102A (en) *	1967-12-08	1969-10-21	American Cyanamid Co	Substituted 7 - (2 - formyl-1-alkoxyvinyl)-7,8-dihydro-6-(hydroxy or methoxy)-6,14-endo (etheno or ethano) codides and morphides
US3931188A (en) *	1974-05-06	1976-01-06	Bristol-Myers Company	3-Hydroxy-5,6-benzomorphinan derivatives
KR100204659B1 (ko) *	1996-05-28	1999-06-15	강재헌	신규한 부프레노핀계 진통제용 화합물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB937214A (en) *	1961-06-02	1963-09-18	J F Macfarlan & Company Ltd	Oripavine derivatives

1964
- 1964-07-08 GB GB28156/64A patent/GB1116595A/en not_active Expired
1965
- 1965-07-07 FR FR23761A patent/FR5192M/fr not_active Expired
- 1965-07-07 ES ES0315046A patent/ES315046A1/es not_active Expired
- 1965-07-07 US US470249A patent/US3329682A/en not_active Expired - Lifetime
- 1965-07-07 NL NL6508759A patent/NL6508759A/xx unknown
- 1965-07-08 BE BE666564D patent/BE666564A/xx unknown

Also Published As

Publication number	Publication date
NL6508759A (es)	1966-01-10
BE666564A (es)	1966-01-10
GB1116595A (en)	1968-06-06
US3329682A (en)	1967-07-04
FR5192M (es)	1967-06-26

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