ES320497A1 - Procedimiento para la obtenciën de 21-pivalato de dexametasona - Google Patents

Info

Publication number

ES320497A1

ES320497A1 ES0320497A ES320497A ES320497A1 ES 320497 A1 ES320497 A1 ES 320497A1 ES 0320497 A ES0320497 A ES 0320497A ES 320497 A ES320497 A ES 320497A ES 320497 A1 ES320497 A1 ES 320497A1

Authority

ES

Spain

Prior art keywords

dexamethasone

pivalate

translation

procedure

obtaining

Prior art date

1965-11-30

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Links

• Espacenet
• Global Dossier
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• XMQRFWOHEPJZPS-JHUFMRCFSA-N [2-[(8s,9r,10s,11s,13s,14s,16r,17r)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)COC(=O)C(C)(C)C)(O)[C@@]1(C)C[C@@H]2O XMQRFWOHEPJZPS-JHUFMRCFSA-N 0.000 title abstract 2
• 238000000034 method Methods 0.000 title abstract 2
• QOSSAOTZNIDXMA-UHFFFAOYSA-N Dicylcohexylcarbodiimide Chemical compound C1CCCCC1N=C=NC1CCCCC1 QOSSAOTZNIDXMA-UHFFFAOYSA-N 0.000 abstract 2
• 239000002253 acid Substances 0.000 abstract 1
• 239000012024 dehydrating agents‎ Substances 0.000 abstract 1
• UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
• 229960003957 dexamethasone Drugs 0.000 abstract 1
• 230000032050 esterification Effects 0.000 abstract 1
• 238000005886 esterification reaction Methods 0.000 abstract 1
• 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1