ES322331A1 - PROCEDURE TO EXTRACT PROTECTIVE ANTIGEN AND TO PREPARE A VACCINE FROM SAME. - Google Patents

PROCEDURE TO EXTRACT PROTECTIVE ANTIGEN AND TO PREPARE A VACCINE FROM SAME.

Info

Publication number
ES322331A1
ES322331A1 ES0322331A ES322331A ES322331A1 ES 322331 A1 ES322331 A1 ES 322331A1 ES 0322331 A ES0322331 A ES 0322331A ES 322331 A ES322331 A ES 322331A ES 322331 A1 ES322331 A1 ES 322331A1
Authority
ES
Spain
Prior art keywords
protective antigen
vaccine
prepare
procedure
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0322331A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES322331A1 publication Critical patent/ES322331A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Method for extracting protective antigen and for preparing a vaccine therefrom, according to which the protective antigen is extracted from the material isolated from the cell wall of B. pertussis, mixing under alkaline conditions, and at a temperature comprised between approximately 2 and 5º C , a suspension of 100 to 2,000 B/ml of said cell wall material and sufficient amount of solution of a salt chosen between sodium chloride and potassium chloride to obtain a final concentration comprised between 0.5 and 1.5 M. (Machine-translation by Google Translate, not legally binding)
ES0322331A 1965-01-19 1966-01-18 PROCEDURE TO EXTRACT PROTECTIVE ANTIGEN AND TO PREPARE A VACCINE FROM SAME. Expired ES322331A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42669165A 1965-01-19 1965-01-19

Publications (1)

Publication Number Publication Date
ES322331A1 true ES322331A1 (en) 1966-11-16

Family

ID=23691819

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0322331A Expired ES322331A1 (en) 1965-01-19 1966-01-18 PROCEDURE TO EXTRACT PROTECTIVE ANTIGEN AND TO PREPARE A VACCINE FROM SAME.

Country Status (11)

Country Link
BE (1) BE675310A (en)
BR (1) BR6676474D0 (en)
DE (1) DE1617605C3 (en)
DK (1) DK115720B (en)
ES (1) ES322331A1 (en)
FR (2) FR1475742A (en)
GB (1) GB1119543A (en)
IL (1) IL24946A (en)
NL (1) NL6600703A (en)
NO (1) NO116869B (en)
SE (1) SE326797B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ188211A (en) * 1977-10-28 1984-09-28 American Cyanamid Co Isolation of polyribosyl ribitol phosphate(prp)from haemophilus influenzae type b;vaccine comprising prp and bordetellapertussis antigens
DE3043291A1 (en) * 1980-11-17 1982-07-01 Dso Pharmachim Whooping cough vaccine - contg. live Bordetella pertussis EM 1964
US4474758A (en) * 1981-11-19 1984-10-02 American Cyanamid Company Haemophilus influenzae type b and pertussis outer membrane component combined vaccine
US6479277B2 (en) * 1997-06-04 2002-11-12 Cellular Improvements Ltd. Method and apparatus for disruption of biological material

Also Published As

Publication number Publication date
FR1475742A (en) 1967-04-07
FR5550M (en) 1967-11-20
IL24946A (en) 1969-05-28
DE1617605B2 (en) 1974-01-31
SE326797B (en) 1970-08-03
DE1617605A1 (en) 1971-04-01
DE1617605C3 (en) 1974-08-29
DK115720B (en) 1969-11-03
BE675310A (en) 1966-07-19
NO116869B (en) 1969-06-02
GB1119543A (en) 1968-07-10
BR6676474D0 (en) 1973-09-11
NL6600703A (en) 1966-07-20

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