ES329014A1 - A procedure for the preparation of benzimidazoles. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of benzimidazoles. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES329014A1 ES329014A1 ES0329014A ES329014A ES329014A1 ES 329014 A1 ES329014 A1 ES 329014A1 ES 0329014 A ES0329014 A ES 0329014A ES 329014 A ES329014 A ES 329014A ES 329014 A1 ES329014 A1 ES 329014A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- translation
- preparation
- machine
- benzimidazoles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001556 benzimidazoles Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 abstract 1
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 abstract 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001356 alkyl thiols Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000002577 pseudohalo group Chemical group 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- PVFOMCVHYWHZJE-UHFFFAOYSA-N trichloroacetyl chloride Chemical compound ClC(=O)C(Cl)(Cl)Cl PVFOMCVHYWHZJE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
A process for the preparation of substituted benzimidazoles of the formula ** (See formula) ** which comprises reacting the ortho-phenylenediamine of the formula ** (See formula) ** with trichloroacetyl chloride; in the formulas set forth above, R1 is hydrogen, alkyl, substituted alkyl, aryl or substituted aryl, R2, R3, R4 and R5 are the same or different and are selected from the group comprising hydrogen, alkyl, alkoxy, nitro, halogen, pseudo halogen, substituted alkyl, carboxy, disubstituted amino, alkyl thiol and oxygenated derivatives thereof, sulfonic acid, acid halide or a heterocyclic ring linked to the benzimidazole system by a nitrogen atom. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB29584/65A GB1138823A (en) | 1965-07-13 | 1965-07-13 | Process for the preparation of substituted benzimidazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES329014A1 true ES329014A1 (en) | 1967-05-01 |
Family
ID=10293852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0329014A Expired ES329014A1 (en) | 1965-07-13 | 1966-07-12 | A procedure for the preparation of benzimidazoles. (Machine-translation by Google Translate, not legally binding) |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT268270B (en) |
| BE (1) | BE683811A (en) |
| BR (1) | BR6680828D0 (en) |
| CH (1) | CH459233A (en) |
| ES (1) | ES329014A1 (en) |
| FR (1) | FR1503581A (en) |
| GB (1) | GB1138823A (en) |
| LU (1) | LU51495A1 (en) |
| NL (1) | NL6609597A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005500303A (en) * | 2001-06-15 | 2005-01-06 | ジェネンテック・インコーポレーテッド | Human growth hormone antagonist |
-
1965
- 1965-07-13 GB GB29584/65A patent/GB1138823A/en not_active Expired
-
1966
- 1966-06-30 BR BR180828/66A patent/BR6680828D0/en unknown
- 1966-07-06 LU LU51495A patent/LU51495A1/xx unknown
- 1966-07-07 BE BE683811D patent/BE683811A/xx unknown
- 1966-07-08 NL NL6609597A patent/NL6609597A/xx unknown
- 1966-07-08 CH CH992166A patent/CH459233A/en unknown
- 1966-07-11 AT AT663166A patent/AT268270B/en active
- 1966-07-12 ES ES0329014A patent/ES329014A1/en not_active Expired
- 1966-07-13 FR FR69330A patent/FR1503581A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6680828D0 (en) | 1973-11-13 |
| LU51495A1 (en) | 1967-01-06 |
| CH459233A (en) | 1968-07-15 |
| GB1138823A (en) | 1969-01-01 |
| FR1503581A (en) | 1967-12-01 |
| BE683811A (en) | 1967-01-09 |
| AT268270B (en) | 1969-02-10 |
| NL6609597A (en) | 1967-01-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES394421A1 (en) | Phenyl-imidazolylalkanyl derivatives | |
| ES336020A1 (en) | Procedure for the preparation of new derivatives of imidazol. (Machine-translation by Google Translate, not legally binding) | |
| ES424483A1 (en) | Hererocyclic derivatives of a guanidine | |
| ES450381A1 (en) | Indaneacetic acid derivatives | |
| ES324834A1 (en) | Improved improvements in the preparation of herbicidal compositions that comprise a substituteed benzymidazole mixture. (Machine-translation by Google Translate, not legally binding) | |
| ES336066A1 (en) | Procedure for the preparation of cylopropan diarylic derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES324565A1 (en) | Procedure for preparing substituteed benzymidazoles. (Machine-translation by Google Translate, not legally binding) | |
| ES332061A1 (en) | PROCEDURE TO PREPARE 3,6-PYRIDAZINE DISUSTITUTED. | |
| ES419019A1 (en) | Indolo-2,3-c quinolinone derivatives | |
| ES425576A1 (en) | Pyrazoles and process for their preparation | |
| ES323401A1 (en) | A procedure that includes the use, as insecticide, of a benzymidazole. (Machine-translation by Google Translate, not legally binding) | |
| ES329580A1 (en) | A procedure for the preparation of substituted benzymidazoles. (Machine-translation by Google Translate, not legally binding) | |
| GB1138823A (en) | Process for the preparation of substituted benzimidazoles | |
| ES308860A1 (en) | Improvements introduced in the preparation of physiologically active compositions. (Machine-translation by Google Translate, not legally binding) | |
| ES392665A1 (en) | Novel process for preparing i-substituted benzodiazepine derivatives | |
| ES392065A1 (en) | A PROCEDURE FOR THE PREPARATION OF A HYDRAZE-NIO SALT. | |
| ES391118A1 (en) | Novel glucuronic acid derivatives and process for the preparation thereof | |
| ES291226A1 (en) | Procedure for the obtaining of new colors (Machine-translation by Google Translate, not legally binding) | |
| ES291049A1 (en) | Procedure for the preparation of new derivatives of 3-azabiciclo- (3,2,2) -nonano (Machine-translation by Google Translate, not legally binding) | |
| ES322851A1 (en) | Procedure for the synthesis of basic derivatives of dihidro-1,3-benzoxacin-2,4-diona. (Machine-translation by Google Translate, not legally binding) | |
| ES412248A1 (en) | O2,2-anhydro-1- beta-d-arabino-furanosyl-cytosine derivatives methods for their preparation and related procedures | |
| ES251042A1 (en) | Procedure for the obtaining of new hydracides (Machine-translation by Google Translate, not legally binding) | |
| ES395875A1 (en) | A procedure for the preparation of indol derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES426329A1 (en) | A PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF 1,2,3,4-TETRAHIDROISOQUINOLEINA. | |
| ES350187A1 (en) | Procedure for the preparation of furazan derivatives. (Machine-translation by Google Translate, not legally binding) |