ES333365A1 - Procedimiento para la preparacion de una composicion farmaceutica. - Google Patents
Procedimiento para la preparacion de una composicion farmaceutica.Info
- Publication number
- ES333365A1 ES333365A1 ES0333365A ES333365A ES333365A1 ES 333365 A1 ES333365 A1 ES 333365A1 ES 0333365 A ES0333365 A ES 0333365A ES 333365 A ES333365 A ES 333365A ES 333365 A1 ES333365 A1 ES 333365A1
- Authority
- ES
- Spain
- Prior art keywords
- acetylsalicylic acid
- ethylcellulose
- particles
- pharmaceutical composition
- millimeters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 5
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 5
- 239000002245 particle Substances 0.000 abstract 5
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 4
- 239000001856 Ethyl cellulose Substances 0.000 abstract 4
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 4
- 229920001249 ethyl cellulose Polymers 0.000 abstract 4
- 230000000717 retained effect Effects 0.000 abstract 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 abstract 2
- 238000013019 agitation Methods 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 abstract 1
- 229960004889 salicylic acid Drugs 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50852865A | 1965-11-18 | 1965-11-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES333365A1 true ES333365A1 (es) | 1967-07-16 |
Family
ID=24023098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0333365A Expired ES333365A1 (es) | 1965-11-18 | 1966-11-15 | Procedimiento para la preparacion de una composicion farmaceutica. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3488418A (es) |
| BR (1) | BR6678816D0 (es) |
| DE (1) | DE1617374C2 (es) |
| ES (1) | ES333365A1 (es) |
| GB (1) | GB1116438A (es) |
| IT (1) | IT1193741B (es) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5788M (es) * | 1965-11-18 | 1968-03-18 | ||
| NL7112083A (es) * | 1970-09-16 | 1972-03-20 | ||
| US4025613A (en) * | 1971-07-19 | 1977-05-24 | Richard G. Powers | Timed-release aspirin |
| BE791458A (fr) * | 1972-07-31 | 1973-05-16 | Merck & Co Inc | Produit microencapsule |
| DE2347713C3 (de) * | 1972-09-25 | 1980-03-06 | Warner-Lambert Co., Morris Plains, N.J. (V.St.A.) | Acetylsalicylsäurekautablette |
| JPS4962623A (es) * | 1972-10-18 | 1974-06-18 | ||
| FR2236483B1 (es) * | 1973-07-12 | 1976-11-12 | Choay Sa | |
| GB1561204A (en) * | 1977-06-01 | 1980-02-13 | Ici Ltd | Sustained release pharmaceutical composition |
| US4153677A (en) * | 1978-05-18 | 1979-05-08 | Sterling Drug Inc. | Controlled-release composition |
| US4316884A (en) * | 1979-01-25 | 1982-02-23 | Adria Laboratories, Inc. | Sustained release pharmaceutical formulation |
| US4508702A (en) * | 1982-06-14 | 1985-04-02 | Key Pharmaceuticals, Inc. | Sustained release aspirin |
| US4507276A (en) * | 1982-08-20 | 1985-03-26 | Bristol-Myers Company | Analgesic capsule |
| HU187215B (en) * | 1983-01-26 | 1985-11-28 | Egyt Gyogyszervegyeszeti Gyar | Method for producing pharmaceutical product of high actor content and prolonged effect |
| US4555399A (en) * | 1983-11-18 | 1985-11-26 | Key Pharmaceuticals, Inc. | Aspirin tablet |
| DE3508097A1 (de) * | 1984-07-21 | 1986-02-06 | Hoechst Ag, 6230 Frankfurt | Kombinationspraeparat aus xanthinderivaten und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung |
| US4937076A (en) * | 1984-08-10 | 1990-06-26 | Combe Incorporated | Chewable aspirin and buffering material tablet and method for producing same |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US4867984A (en) * | 1984-11-06 | 1989-09-19 | Nagin K. Patel | Drug in bead form and process for preparing same |
| US4874614A (en) * | 1985-03-25 | 1989-10-17 | Abbott Laboratories | Pharmaceutical tableting method |
| US4863741A (en) * | 1985-03-25 | 1989-09-05 | Abbott Laboratories | Tablet composition for drug combinations |
| US4710384A (en) * | 1986-07-28 | 1987-12-01 | Avner Rotman | Sustained release tablets made from microcapsules |
| US4786509A (en) * | 1987-05-18 | 1988-11-22 | Schering Corporation | Dry sustained release theophylline oral formulation |
| US5026559A (en) * | 1989-04-03 | 1991-06-25 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
| US4983401A (en) * | 1989-05-22 | 1991-01-08 | Kinaform Technology, Inc. | Sustained release pharmaceutical preparations having pH controlled membrane coatings |
| IE64128B1 (en) * | 1990-02-26 | 1995-07-12 | Byrne Rynne Holdings Ltd | A pharmaceutical composition |
| US5376384A (en) * | 1992-12-23 | 1994-12-27 | Kinaform Technology, Inc. | Delayed, sustained-release pharmaceutical preparation |
| FR2741534B1 (fr) * | 1995-11-23 | 1998-09-11 | Mazal Pharma | Composition pharmaceutique stable a base d'acide acetylsalicylique et de tocopherol |
| FR2766089B1 (fr) * | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
| GB9814215D0 (en) * | 1998-07-01 | 1998-09-02 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
| BR0013719A (pt) | 1999-09-02 | 2002-07-23 | Nostrum Pharmaceuticals Inc | Dosagem oral de liberaçâo controlada, apropriada para administração oral |
| US20040131662A1 (en) | 2003-11-12 | 2004-07-08 | Davidson Robert S. | Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films |
| US9561182B2 (en) * | 2003-08-22 | 2017-02-07 | Cure Pharmaceutical Corporation | Edible films for administration of medicaments to animals, methods for their manufacture and methods for their use for the treatment of animals |
| US8999372B2 (en) * | 2002-11-14 | 2015-04-07 | Cure Pharmaceutical Corporation | Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use |
| US20040191302A1 (en) | 2003-03-28 | 2004-09-30 | Davidson Robert S. | Method and apparatus for minimizing heat, moisture, and shear damage to medicants and other compositions during incorporation of same with edible films |
| US7387793B2 (en) | 2003-11-14 | 2008-06-17 | Eurand, Inc. | Modified release dosage forms of skeletal muscle relaxants |
| CA2883060C (en) * | 2005-11-09 | 2019-01-08 | Philera New Zealand Limited | Treatment of mitochondria-related diseases and improvement of age-related metabolic deficits |
| WO2010081722A2 (en) * | 2009-01-16 | 2010-07-22 | Add Technologies Ltd. | Orally disintegrating tablets for the treatment of pain |
| CA2845617A1 (en) | 2011-08-18 | 2013-02-21 | Otago Innovation Limited | Cardiovascular therapeutics |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3146168A (en) * | 1962-04-10 | 1964-08-25 | Fmc Corp | Manufacture of pharmaceutical preparations containing cellulose crystallite aggregates |
| US3115441A (en) * | 1962-06-06 | 1963-12-24 | Victor M Hermelin | Timed release pharmaceutical preparations and method of making the same |
| US3155590A (en) * | 1962-08-02 | 1964-11-03 | Ncr Co | Encapsulation process and its product |
| US3341416A (en) * | 1963-12-11 | 1967-09-12 | Ncr Co | Encapsulation of aspirin in ethylcellulose and its product |
-
1965
- 1965-11-18 US US508528A patent/US3488418A/en not_active Expired - Lifetime
-
1966
- 1966-04-13 IT IT8225/66A patent/IT1193741B/it active
- 1966-04-13 GB GB16221/66A patent/GB1116438A/en not_active Expired
- 1966-04-18 BR BR178816/66A patent/BR6678816D0/pt unknown
- 1966-06-01 DE DE1617374A patent/DE1617374C2/de not_active Expired
- 1966-11-15 ES ES0333365A patent/ES333365A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6678816D0 (pt) | 1973-09-18 |
| GB1116438A (en) | 1968-06-06 |
| IT1193741B (it) | 1988-08-24 |
| US3488418A (en) | 1970-01-06 |
| DE1617374A1 (de) | 1971-04-01 |
| DE1617374C2 (de) | 1984-04-26 |
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