ES334879A2 - Procedure for the preparation of an amidine or a corresponding acid addition salt. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of an amidine or a corresponding acid addition salt. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES334879A2 ES334879A2 ES0334879A ES334879A ES334879A2 ES 334879 A2 ES334879 A2 ES 334879A2 ES 0334879 A ES0334879 A ES 0334879A ES 334879 A ES334879 A ES 334879A ES 334879 A2 ES334879 A2 ES 334879A2
- Authority
- ES
- Spain
- Prior art keywords
- group
- phenyl
- substituted
- amidine
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000001409 amidines Chemical class 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004429 atom Chemical group 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical class [H]N([H])* 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/38—Amides of thiocarboxylic acids
- C07C327/48—Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Improvements introduced in the subject of the main patent No. 315,014 by a process for the preparation of an amidine or a corresponding acid addition salt characterized in that an imidocarbonyl compound is reacted with ammonia, a primary amine or a reducing agent in order to form an amidine that frames the formula: ** (See formula) ** wherein one of x1 and X2 is a phenyl group substituted in at least one position with a group or with a group X3O, X3 being a phenyl or phenylalkyl moiety, with each phenyl ring being in the whole group optionally further substituted with substituent (s) each being a halogen atom or an alkyl, alkoxy, hydroxy, alkylthio, alkylsulfinyl or aminosulfonyl group; the other X1 and X2 is an X3-substituted or X3O-substituted phenyl group as defined above, or a phenyl or thien-2-yl ring optionally substituted with substituent (s) each being a halogen atom or an alkyl group , alkoxy, hydroxy, alkylthio, alkylsulfinyl or alkylsulfonyl; A 'is a straight or branched divalent group containing from two to six carbon atoms and one or two divalent atoms each being an oxygen or sulfur atom, as long as there are at least two carbon atoms between the divalent atom and the carbon atom. group -NH- and between the two divalent atoms; and A2 is a straight or branched chain alkylene group containing from one to four carbon atoms: each of the "alkyl" and "alkoxy" groups containing from one to four carbon atoms or a respective acid addition salt. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB54489/65A GB1145278A (en) | 1964-07-07 | 1965-12-23 | Amidine derivatives, processes for their preparation, and compositions incorporating them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES334879A2 true ES334879A2 (en) | 1967-11-01 |
Family
ID=10471168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0334879A Expired ES334879A2 (en) | 1965-12-23 | 1966-12-23 | Procedure for the preparation of an amidine or a corresponding acid addition salt. (Machine-translation by Google Translate, not legally binding) |
Country Status (7)
| Country | Link |
|---|---|
| AT (1) | AT294037B (en) |
| CS (1) | CS152438B2 (en) |
| DK (1) | DK137270B (en) |
| ES (1) | ES334879A2 (en) |
| FI (1) | FI44606C (en) |
| NO (1) | NO120031B (en) |
| SE (1) | SE353320B (en) |
-
1966
- 1966-12-15 NO NO166009A patent/NO120031B/no unknown
- 1966-12-21 AT AT1175766A patent/AT294037B/en not_active IP Right Cessation
- 1966-12-21 SE SE17506/66D patent/SE353320B/xx unknown
- 1966-12-22 FI FI663413A patent/FI44606C/en active
- 1966-12-23 CS CS8279A patent/CS152438B2/cs unknown
- 1966-12-23 ES ES0334879A patent/ES334879A2/en not_active Expired
- 1966-12-23 DK DK666466AA patent/DK137270B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI44606B (en) | 1971-08-31 |
| DK137270C (en) | 1978-07-17 |
| NO120031B (en) | 1970-08-17 |
| AT294037B (en) | 1971-11-10 |
| SE353320B (en) | 1973-01-29 |
| FI44606C (en) | 1971-12-10 |
| DK137270B (en) | 1978-02-13 |
| CS152438B2 (en) | 1973-12-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES375013A1 (en) | Pyrrolobenzodiazepinone derivatives | |
| ES407390A1 (en) | Pyrazoline compounds | |
| GB1441056A (en) | Phenyl-pyridazines their preparation and use as herbicides | |
| FI832639A0 (en) | FOUNDATION MAKING MACHINES | |
| ES312384A1 (en) | Procedure for the preparation of fenilalquilaminoguanidinas. (Machine-translation by Google Translate, not legally binding) | |
| GB1109786A (en) | Benzimidazole ethers | |
| ES461979A1 (en) | Derivatives of substituted n-alkyl imidazoles having pharmaceutical activity | |
| GB1049960A (en) | Phosphorus-containing esters | |
| ES334879A2 (en) | Procedure for the preparation of an amidine or a corresponding acid addition salt. (Machine-translation by Google Translate, not legally binding) | |
| ES315014A1 (en) | Procedures for the preparation of an amidine or a corresponding acid addition salt. (Machine-translation by Google Translate, not legally binding) | |
| ES418827A1 (en) | 2-aminoindane derivatives | |
| ES423104A1 (en) | Procedure for preparing heterociclic anilides. (Machine-translation by Google Translate, not legally binding) | |
| GB1512179A (en) | Thionobenzenephosphonic acid 0,0-diesters and their use as insecticides and acaricides | |
| ES443201A1 (en) | PROCEDURE FOR PREPARING DERIVATIVES OF 5-NITROIMIDAZOLE. | |
| ES376983A1 (en) | Chemical compounds, processes for their preparation, and pharmaceutical compositions incorporating the same | |
| GB1229993A (en) | ||
| GB1317598A (en) | Pesticidal adducts of thiophosphorus acids and n-vinyl compounds and process of preparing same | |
| GB1314937A (en) | Phenyl-urea derivatives and herbicidal | |
| GB1026929A (en) | Improvements in or relating to 2-aryl-4,6,7-triaminopteridines | |
| DE2967195D1 (en) | Derivatives of substituted n-alkyl imidazoles, their preparation and these compounds for pharmaceutical use | |
| ES381429A1 (en) | Penicillins | |
| ES340047A1 (en) | PROCEDURE FOR THE PRODUCTION OF SULPHONILIC UREA DERIVATIVES. | |
| GB1087001A (en) | Novel tropylium compounds and process for preparing the same | |
| ES388284A1 (en) | Dihydrobenzthiazine-s-dioxides and their preparation | |
| ES331239A3 (en) | A procedure for preparing fenotiazine compounds. (Machine-translation by Google Translate, not legally binding) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170629 |