ES336531A1 - Procedimiento para preparar derivados del acido d-lisergi- co. - Google Patents

Procedimiento para preparar derivados del acido d-lisergi- co.

Info

Publication number: ES336531A1
Authority: ES; Spain
Prior art keywords: acid; lysergic; lysergic acid; carbons; dihydro
Prior art date: 1966-02-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES336531A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-02-08

Filing date

1967-02-07

Publication date

1968-04-01

1967-02-07 Application filed by Sandoz AG filed Critical Sandoz AG

1968-04-01 Publication of ES336531A1 publication Critical patent/ES336531A1/es

Status Expired legal-status Critical Current

Links

ZAGRKAFMISFKIO-QMTHXVAHSA-N lysergic acid Chemical class C1=CC(C2=C[C@H](CN([C@@H]2C2)C)C(O)=O)=C3C2=CNC3=C1 ZAGRKAFMISFKIO-QMTHXVAHSA-N 0.000 title abstract 3
239000002253 acid Substances 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
ORBSYPFBZQJNJE-MPKXVKKWSA-N (6ar,9r,10ar)-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carboxylic acid Chemical compound C1=CC([C@H]2C[C@H](CN([C@@H]2C2)C)C(O)=O)=C3C2=CNC3=C1 ORBSYPFBZQJNJE-MPKXVKKWSA-N 0.000 abstract 1
NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
ZAGRKAFMISFKIO-UHFFFAOYSA-N Isolysergic acid Natural products C1=CC(C2=CC(CN(C2C2)C)C(O)=O)=C3C2=CNC3=C1 ZAGRKAFMISFKIO-UHFFFAOYSA-N 0.000 abstract 1
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
150000008064 anhydrides Chemical class 0.000 abstract 1
230000003042 antagnostic effect Effects 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
150000005840 aryl radicals Chemical class 0.000 abstract 1
150000001540 azides Chemical class 0.000 abstract 1
125000001246 bromo group Chemical group Br* 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
230000003993 interaction Effects 0.000 abstract 1
239000003176 neuroleptic agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
-1 piperazine compound Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229940076279 serotonin Drugs 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1
235000011149 sulphuric acid Nutrition 0.000 abstract 1
239000001117 sulphuric acid Substances 0.000 abstract 1
239000000829 suppository Substances 0.000 abstract 1
235000020357 syrup Nutrition 0.000 abstract 1
239000006188 syrup Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
- C07D457/08—Lysergic acid amides in which the amide nitrogen is a member of a heterocyclic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES336531A 1966-02-08 1967-02-07 Procedimiento para preparar derivados del acido d-lisergi- co. Expired ES336531A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH175666A CH475252A (de)	1966-02-08	1966-02-08	Verfahren zur Herstellung neuer Lysergsäure-Derivate
CH1753066A CH493521A (de)	1966-02-08	1966-12-09	Verfahren zur Herstellung neuer heterocyclischer Verbindungen

Publications (1)

Publication Number	Publication Date
ES336531A1 true ES336531A1 (es)	1968-04-01

Family

ID=25688570

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES336531A Expired ES336531A1 (es)	1966-02-08	1967-02-07	Procedimiento para preparar derivados del acido d-lisergi- co.

Country Status (8)

Country	Link
CH (2)	CH475252A (de)
DE (1)	DE1695682A1 (de)
DK (1)	DK125175B (de)
ES (1)	ES336531A1 (de)
FI (1)	FI47189C (de)
FR (2)	FR1510553A (de)
GB (1)	GB1154682A (de)
SE (1)	SE324785B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE564825A (de) *	1957-02-15
IL41409A (en) *	1972-02-04	1977-04-29	Richter Gedeon Vegyeszet	Lysergic acid amides and process for their preparation
HU169073B (de) *	1974-05-28	1976-09-28
GB9711043D0 (en) *	1997-05-29	1997-07-23	Ciba Geigy Ag	Organic compounds

1966
- 1966-02-08 CH CH175666A patent/CH475252A/de not_active IP Right Cessation
- 1966-12-09 CH CH1753066A patent/CH493521A/de not_active IP Right Cessation
1967
- 1967-01-12 GB GB181367A patent/GB1154682A/en not_active Expired
- 1967-02-04 DE DE19671695682 patent/DE1695682A1/de active Pending
- 1967-02-06 FI FI33867A patent/FI47189C/fi active
- 1967-02-07 ES ES336531A patent/ES336531A1/es not_active Expired
- 1967-02-07 FR FR93979A patent/FR1510553A/fr not_active Expired
- 1967-02-07 DK DK66267A patent/DK125175B/da unknown
- 1967-02-07 SE SE1702/67A patent/SE324785B/xx unknown
- 1967-05-03 FR FR105145A patent/FR6554M/fr not_active Expired

Also Published As

Publication number	Publication date
SE324785B (de)	1970-06-15
CH475252A (de)	1969-07-15
CH493521A (de)	1970-07-15
FR1510553A (fr)	1968-01-19
FI47189B (de)	1973-07-02
DK125175B (da)	1973-01-08
FI47189C (fi)	1973-10-10
FR6554M (de)	1968-12-23
GB1154682A (en)	1969-06-11
DE1695682A1 (de)	1971-04-08

Similar Documents

Publication	Publication Date	Title
GB1299621A (en)	1972-12-13	0-substituted-2-methylbenzimidazoles
IE41528L (en)	1975-04-27	Furfuryl-benzomorphane derivatives.
ES291240A1 (es)	1964-03-01	Procedimiento para la obtenciën de nuevos derivados heterociclicos
ES336531A1 (es)	1968-04-01	Procedimiento para preparar derivados del acido d-lisergi- co.
ES265136A1 (es)	1961-08-16	Procedimiento de obtenciën de derivados de tiaxantena
GB1228736A (de)	1971-04-15
GB1169945A (en)	1969-11-05	Pharmaceutical Compositions containing Diphenylalkyl-amine Derivatives
GB1059994A (en)	1967-02-22	Preparation of 3-amino-2-pyrazolin-5-one derivatives
GB1348142A (en)	1974-03-13	Derivatives of alpha-cyanacrylic acid their production and use as stabilizers for organic materials
GB1188248A (en)	1970-04-15	2-Isothiouronium-Methyl-Quinoxaline-1,4,di-N-Oxide-3-Carboxylic Acid Amide Halides
GB1085672A (en)	1967-10-04	Substituted phthalazines
GB1068083A (en)	1967-05-10	í¸-1,2,4-triazolone-(5) derivatives
ES345690A1 (es)	1968-11-16	Procedimiento para la preparacion de 2-aminometil-benzofu- ranos sustituidos.
GB1188197A (en)	1970-04-15	Lysergic Acid Derivatives
GB1069204A (en)	1967-05-17	Improvements in or relating to piperazines
GB1017264A (en)	1966-01-19	Quinazolinone derivatives and the manufacture thereof
ES369889A1 (es)	1971-07-16	Procedimiento para la preparacion de quinoxalin-1,4-dioxi- dos.
ES349555A1 (es)	1969-09-16	Un procedimiento para la preparacion de mucononitrilos.
GB1043853A (en)	1966-09-28	Improvements in or relating to diphenylsulphide compounds
GB1073976A (en)	1967-06-28	New biologically active derivatives of pyrrolidine and the manufacture thereof
ES355551A1 (es)	1970-03-01	Procedimiento para la preparacion de derivados de piperidi-na.
GB1103155A (en)	1968-02-14	Improvements in and relating to quinazolines
ES377508A1 (es)	1973-02-01	Procedimiento para la obtencion de composiciones herbici- das.
ES339128A1 (es)	1968-08-01	Procedimiento para la produccion de n-guanil-3-azabiciclo (3,2,0) heptano-3-carboxamidina.
GB1227965A (de)	1971-04-15