ES338970A3 - Un procedimiento para preparar un compuesto antibiotico de cefalosporina. - Google Patents

Info

Publication number

ES338970A3

ES338970A3 ES338970A ES338970A ES338970A3 ES 338970 A3 ES338970 A3 ES 338970A3 ES 338970 A ES338970 A ES 338970A ES 338970 A ES338970 A ES 338970A ES 338970 A3 ES338970 A3 ES 338970A3

Authority

ES

Spain

Prior art keywords

class consisting

cephalosporin

general formula

carbon atoms

radical

Prior art date

1967-04-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Links

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• 230000003115 biocidal effect Effects 0.000 title abstract 2
• 238000000034 method Methods 0.000 title abstract 2
• 239000003242 anti bacterial agent Substances 0.000 title 1
• 239000002131 composite material Substances 0.000 title 1
• 150000001875 compounds Chemical class 0.000 abstract 5
• 125000004432 carbon atom Chemical group C* 0.000 abstract 4
• HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 4
• 229930186147 Cephalosporin Natural products 0.000 abstract 3
• 229940124587 cephalosporin Drugs 0.000 abstract 3
• 150000001780 cephalosporins Chemical class 0.000 abstract 3
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 3
• 229910052739 hydrogen Inorganic materials 0.000 abstract 3
• 239000001257 hydrogen Substances 0.000 abstract 3
• 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
• 125000001302 tertiary amino group Chemical group 0.000 abstract 3
• -1 bensofuryl Chemical group 0.000 abstract 2
• 125000002619 bicyclic group Chemical group 0.000 abstract 2
• 239000003795 chemical substances by application Substances 0.000 abstract 2
• 239000000470 constituent Substances 0.000 abstract 2
• 108010013043 Acetylesterase Proteins 0.000 abstract 1
• 102100036617 Monoacylglycerol lipase ABHD2 Human genes 0.000 abstract 1
• 125000002252 acyl group Chemical group 0.000 abstract 1
• 125000004423 acyloxy group Chemical group 0.000 abstract 1
• 125000003545 alkoxy group Chemical group 0.000 abstract 1
• 125000000217 alkyl group Chemical group 0.000 abstract 1
• 239000012736 aqueous medium Substances 0.000 abstract 1
• 125000004196 benzothienyl group Chemical group S1C(=CC2=C1C=CC=C2)* 0.000 abstract 1
• 229910052799 carbon Inorganic materials 0.000 abstract 1
• XWCFYHBHOFBVIV-JWKOBGCHSA-N deacetylcephalosporin C Chemical class S1CC(CO)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@H]21 XWCFYHBHOFBVIV-JWKOBGCHSA-N 0.000 abstract 1
• 125000002541 furyl group Chemical group 0.000 abstract 1
• 229910052736 halogen Inorganic materials 0.000 abstract 1
• 150000002367 halogens Chemical class 0.000 abstract 1
• 238000010438 heat treatment Methods 0.000 abstract 1
• 125000001624 naphthyl group Chemical group 0.000 abstract 1
• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
• 238000010992 reflux Methods 0.000 abstract 1
• 230000001105 regulatory effect Effects 0.000 abstract 1
• 125000001424 substituent group Chemical group 0.000 abstract 1
• 238000006467 substitution reaction Methods 0.000 abstract 1
• 150000003512 tertiary amines Chemical class 0.000 abstract 1
• 125000001544 thienyl group Chemical group 0.000 abstract 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1