ES340056A1 - Un procedimiento para preparar un esteroide. - Google Patents
Un procedimiento para preparar un esteroide.Info
- Publication number
- ES340056A1 ES340056A1 ES340056A ES340056A ES340056A1 ES 340056 A1 ES340056 A1 ES 340056A1 ES 340056 A ES340056 A ES 340056A ES 340056 A ES340056 A ES 340056A ES 340056 A1 ES340056 A1 ES 340056A1
- Authority
- ES
- Spain
- Prior art keywords
- cyclopropyl
- alpha
- hydroxy
- oxo
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- YSQFBLFEYNOIBW-UHFFFAOYSA-N lithium;cyclopropane Chemical compound [Li+].C1C[CH-]1 YSQFBLFEYNOIBW-UHFFFAOYSA-N 0.000 abstract 3
- 150000000297 16-estratetraenes Chemical class 0.000 abstract 1
- MNRGTYIVYMTMKH-UHFFFAOYSA-N 2-sulfinylpropane Chemical compound CC(C)=S=O MNRGTYIVYMTMKH-UHFFFAOYSA-N 0.000 abstract 1
- LULAYUGMBFYYEX-UHFFFAOYSA-M 3-chlorobenzoate Chemical compound [O-]C(=O)C1=CC=CC(Cl)=C1 LULAYUGMBFYYEX-UHFFFAOYSA-M 0.000 abstract 1
- QZLYKIGBANMMBK-UGCZWRCOSA-N 5α-Androstane Chemical compound C([C@@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CCC[C@@]2(C)CC1 QZLYKIGBANMMBK-UGCZWRCOSA-N 0.000 abstract 1
- AEMFNILZOJDQLW-QAGGRKNESA-N androst-4-ene-3,17-dione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 AEMFNILZOJDQLW-QAGGRKNESA-N 0.000 abstract 1
- 229960005471 androstenedione Drugs 0.000 abstract 1
- AEMFNILZOJDQLW-UHFFFAOYSA-N androstenedione Natural products O=C1CCC2(C)C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 AEMFNILZOJDQLW-UHFFFAOYSA-N 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 cyclopropyl magnesium halide Chemical class 0.000 abstract 1
- 239000012024 dehydrating agents Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002162 estranes Chemical class 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000000871 hypocholesterolemic effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- LULAYUGMBFYYEX-UHFFFAOYSA-N metachloroperbenzoic acid Natural products OC(=O)C1=CC=CC(Cl)=C1 LULAYUGMBFYYEX-UHFFFAOYSA-N 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 230000001016 myotrophic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001817 pituitary effect Effects 0.000 abstract 1
- 230000001072 progestational effect Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54651466A | 1966-05-02 | 1966-05-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES340056A1 true ES340056A1 (es) | 1968-09-01 |
Family
ID=24180777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES340056A Expired ES340056A1 (es) | 1966-05-02 | 1967-05-02 | Un procedimiento para preparar un esteroide. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3501462A (es) |
| BE (1) | BE697861A (es) |
| ES (1) | ES340056A1 (es) |
| FR (1) | FR6938M (es) |
| GB (1) | GB1188373A (es) |
| GR (1) | GR33801B (es) |
| NL (1) | NL6706170A (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1550343A (en) * | 1975-07-16 | 1979-08-15 | Gist Brocades Nv | Androstane derivatives |
-
1966
- 1966-05-02 US US546514A patent/US3501462A/en not_active Expired - Lifetime
-
1967
- 1967-04-27 GB GB09575/67A patent/GB1188373A/en not_active Expired
- 1967-05-02 BE BE697861D patent/BE697861A/xx unknown
- 1967-05-02 ES ES340056A patent/ES340056A1/es not_active Expired
- 1967-05-02 GR GR670133801A patent/GR33801B/el unknown
- 1967-05-02 NL NL6706170A patent/NL6706170A/xx unknown
- 1967-05-02 FR FR104839A patent/FR6938M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR6938M (es) | 1969-05-12 |
| NL6706170A (es) | 1967-11-03 |
| US3501462A (en) | 1970-03-17 |
| GR33801B (el) | 1968-02-05 |
| GB1188373A (en) | 1970-04-15 |
| BE697861A (es) | 1967-11-03 |
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