ES341056A1 - Procedimiento para la preparacion de morfantridinas 6-basi-camente sustituidas. - Google Patents
Procedimiento para la preparacion de morfantridinas 6-basi-camente sustituidas.Info
- Publication number
- ES341056A1 ES341056A1 ES341056A ES341056A ES341056A1 ES 341056 A1 ES341056 A1 ES 341056A1 ES 341056 A ES341056 A ES 341056A ES 341056 A ES341056 A ES 341056A ES 341056 A1 ES341056 A1 ES 341056A1
- Authority
- ES
- Spain
- Prior art keywords
- reaction
- formula
- morphanthridine
- morphanthridines
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001768 cations Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001408 amides Chemical class 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 abstract 2
- -1 ethylene, trimethylene Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- CYQAYERJWZKYML-UHFFFAOYSA-N phosphorus pentasulfide Chemical compound S1P(S2)(=S)SP3(=S)SP1(=S)SP2(=S)S3 CYQAYERJWZKYML-UHFFFAOYSA-N 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FQUYSHZXSKYCSY-UHFFFAOYSA-N 1,4-diazepane Chemical class C1CNCCNC1 FQUYSHZXSKYCSY-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 150000008425 anthrones Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 1
- 238000010494 dissociation reaction Methods 0.000 abstract 1
- 230000005593 dissociations Effects 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 150000002828 nitro derivatives Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Chemical group CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 abstract 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nonwoven Fabrics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH794366A CH469723A (de) | 1966-06-01 | 1966-06-01 | Verfahren zur Herstellung 6basisch substituierter Morphanthridine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES341056A1 true ES341056A1 (es) | 1968-07-01 |
Family
ID=4332743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES341056A Expired ES341056A1 (es) | 1966-06-01 | 1967-05-27 | Procedimiento para la preparacion de morfantridinas 6-basi-camente sustituidas. |
Country Status (13)
| Country | Link |
|---|---|
| AT (4) | AT271488B (de) |
| BE (1) | BE699280A (de) |
| CH (1) | CH469723A (de) |
| DK (1) | DK117707B (de) |
| ES (1) | ES341056A1 (de) |
| FI (1) | FI46161C (de) |
| FR (1) | FR6504M (de) |
| GB (1) | GB1142596A (de) |
| GR (1) | GR36292B (de) |
| IL (1) | IL28036A (de) |
| NL (1) | NL6707571A (de) |
| NO (1) | NO120792B (de) |
| SE (1) | SE345269B (de) |
-
1966
- 1966-06-01 CH CH794366A patent/CH469723A/de unknown
-
1967
- 1967-05-25 IL IL2803667A patent/IL28036A/en unknown
- 1967-05-25 GB GB24378/67A patent/GB1142596A/en not_active Expired
- 1967-05-25 FI FI148767A patent/FI46161C/fi active
- 1967-05-27 ES ES341056A patent/ES341056A1/es not_active Expired
- 1967-05-29 AT AT488768A patent/AT271488B/de active
- 1967-05-29 FR FR108222A patent/FR6504M/fr not_active Expired
- 1967-05-29 AT AT488868A patent/AT270663B/de active
- 1967-05-29 AT AT498567A patent/AT271480B/de active
- 1967-05-29 AT AT488968A patent/AT270664B/de active
- 1967-05-30 GR GR670136292A patent/GR36292B/el unknown
- 1967-05-31 NO NO16840167A patent/NO120792B/no unknown
- 1967-05-31 SE SE763967A patent/SE345269B/xx unknown
- 1967-05-31 NL NL6707571A patent/NL6707571A/xx unknown
- 1967-05-31 DK DK283867A patent/DK117707B/da unknown
- 1967-05-31 BE BE699280D patent/BE699280A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT270663B (de) | 1969-05-12 |
| CH469723A (de) | 1969-03-15 |
| GR36292B (el) | 1969-01-20 |
| FI46161B (de) | 1972-10-02 |
| AT270664B (de) | 1969-05-12 |
| AT271480B (de) | 1969-06-10 |
| AT271488B (de) | 1969-06-10 |
| DK117707B (da) | 1970-05-25 |
| GB1142596A (en) | 1969-02-12 |
| SE345269B (de) | 1972-05-23 |
| FR6504M (de) | 1968-12-02 |
| BE699280A (de) | 1967-11-30 |
| IL28036A (en) | 1972-02-29 |
| FI46161C (fi) | 1973-01-10 |
| NO120792B (de) | 1970-12-07 |
| NL6707571A (de) | 1967-12-04 |
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