ES342646A1 - Procedimiento para la fabricacion de nuevas amidas y este- ramidas n-sustituidas de acido fosforico y tiofosforico. - Google Patents

Procedimiento para la fabricacion de nuevas amidas y este- ramidas n-sustituidas de acido fosforico y tiofosforico.

Info

Publication number: ES342646A1
Authority: ES; Spain
Prior art keywords: formula; compound; halogen; reacting; alkyl
Prior art date: 1966-07-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES342646A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ASTA-WERKE A G CHEMISCHE FABRIK

Asta Medica GmbH

Original Assignee

ASTA-WERKE A G CHEMISCHE FABRIK

Asta Werke AG Chemische Fabrik

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-07-11

Filing date

1967-07-05

Publication date

1968-10-16

1967-07-05 Application filed by ASTA-WERKE A G CHEMISCHE FABRIK, Asta Werke AG Chemische Fabrik filed Critical ASTA-WERKE A G CHEMISCHE FABRIK

1968-10-16 Publication of ES342646A1 publication Critical patent/ES342646A1/es

Status Expired legal-status Critical Current

Links

-1 N-Substituted Amides Chemical class 0.000 title abstract 2
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 title 1
RYYWUUFWQRZTIU-UHFFFAOYSA-N Thiophosphoric acid Chemical compound OP(O)(S)=O RYYWUUFWQRZTIU-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 8
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052736 halogen Inorganic materials 0.000 abstract 4
150000002367 halogens Chemical class 0.000 abstract 4
125000005843 halogen group Chemical group 0.000 abstract 3
239000002253 acid Substances 0.000 abstract 2
239000011230 binding agent Substances 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
239000005864 Sulphur Substances 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
230000002140 halogenating effect Effects 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES342646A 1966-07-11 1967-07-05 Procedimiento para la fabricacion de nuevas amidas y este- ramidas n-sustituidas de acido fosforico y tiofosforico. Expired ES342646A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE1966A0052989 DE1645921C3 (de)	1966-07-11	1966-07-11	2-Oxo-13,2-osazaphosphorinane, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
US10656971A	1971-01-14	1971-01-14

Publications (1)

Publication Number	Publication Date
ES342646A1 true ES342646A1 (es)	1968-10-16

Family

ID=25964360

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES342646A Expired ES342646A1 (es)	1966-07-11	1967-07-05	Procedimiento para la fabricacion de nuevas amidas y este- ramidas n-sustituidas de acido fosforico y tiofosforico.

Country Status (12)

Country	Link
BE (1)	BE700711A (fr)
CH (1)	CH510699A (fr)
DE (1)	DE1645921C3 (fr)
DK (1)	DK119407B (fr)
ES (1)	ES342646A1 (fr)
FI (1)	FI48602C (fr)
FR (1)	FR6695M (fr)
GB (1)	GB1188159A (fr)
LU (1)	LU53924A1 (fr)
NL (1)	NL148323B (fr)
SE (1)	SE330174B (fr)
YU (2)	YU36187B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3220432A1 (de) *	1981-03-24	1983-12-01	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Oxazaphosphorin-4-thio-alkansulfonsaeure, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate
DE3111428A1 (de) *	1981-03-24	1982-10-07	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3220672A1 (de) *	1981-03-24	1983-12-08	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Cis-oxazaphosphorin-4-thio-alkansulfonsaeuren, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate
DE3133077A1 (de) *	1981-08-21	1983-03-10	Henkel KGaA, 4000 Düsseldorf	Neue cytostatisch wirksame epoxidgruppen tragende 1,3,2-oxazaphosphorin-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung in pharmazeutischen zubereitungen
EP0235661A3 (fr) *	1986-02-22	1989-01-11	ASTA Pharma Aktiengesellschaft	Composés hétérocycliques avec un reste[(N,N-bis(chloro-2-éthyl)-diamido-phosphoryl-oxy)-2 éthyl]-2
ES2021771B3 (es) *	1987-03-06	1991-11-16	Asta Pharma Ag	Procedimiento para la obtencion de ifosfamida con propiedades mejoradas.
GB9323399D0 (en) *	1993-11-12	1994-01-05	Univ Newcastle Ventures Ltd	Pharmaceutical formulations
DE19739159C1 (de) *	1997-09-06	1999-01-28	Asta Medica Ag	Verfahren zur Herstellung von Oxazaphosphorin-2-aminen

1966
- 1966-07-11 DE DE1966A0052989 patent/DE1645921C3/de not_active Expired
1967
- 1967-06-20 LU LU53924D patent/LU53924A1/xx unknown
- 1967-06-30 BE BE700711D patent/BE700711A/xx not_active IP Right Cessation
- 1967-06-30 SE SE09970/67*A patent/SE330174B/xx unknown
- 1967-07-05 ES ES342646A patent/ES342646A1/es not_active Expired
- 1967-07-06 FI FI671879A patent/FI48602C/fi active
- 1967-07-07 CH CH967367A patent/CH510699A/de not_active IP Right Cessation
- 1967-07-10 DK DK353667AA patent/DK119407B/da not_active IP Right Cessation
- 1967-07-11 FR FR113841A patent/FR6695M/fr not_active Expired
- 1967-07-11 GB GB31849/67A patent/GB1188159A/en not_active Expired
- 1967-07-11 NL NL676709606A patent/NL148323B/xx not_active IP Right Cessation
1972
- 1972-12-28 YU YU03284/72A patent/YU36187B/xx unknown
1974
- 1974-08-16 YU YU2251/74A patent/YU39527B/xx unknown

Also Published As

Publication number	Publication date
CH510699A (de)	1971-07-31
DE1645921B2 (de)	1978-02-09
NL148323B (nl)	1976-01-15
SE330174B (fr)	1970-11-09
LU53924A1 (fr)	1967-08-21
YU39527B (en)	1984-12-31
YU225174A (en)	1982-02-28
FI48602C (fi)	1974-11-11
DK119407B (da)	1970-12-28
FR6695M (fr)	1969-02-10
BE700711A (fr)	1967-12-01
FI48602B (fr)	1974-07-31
YU36187B (en)	1982-02-25
GB1188159A (en)	1970-04-15
NL6709606A (fr)	1968-01-12
DE1645921A1 (de)	1970-07-16
DE1645921C3 (de)	1978-10-12
YU328472A (en)	1981-06-30

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