ES345831A1 - Procedimiento para la preparacion de nuevos acidos fenila- ceticos sustituidos. - Google Patents
Procedimiento para la preparacion de nuevos acidos fenila- ceticos sustituidos.Info
- Publication number
- ES345831A1 ES345831A1 ES345831A ES345831A ES345831A1 ES 345831 A1 ES345831 A1 ES 345831A1 ES 345831 A ES345831 A ES 345831A ES 345831 A ES345831 A ES 345831A ES 345831 A1 ES345831 A1 ES 345831A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- anilino
- hydrogen
- alkyl
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical class OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- SHYRNAJCPIECFE-UHFFFAOYSA-N 1-(2-anilinophenyl)ethanone Chemical compound CC(=O)C1=CC=CC=C1NC1=CC=CC=C1 SHYRNAJCPIECFE-UHFFFAOYSA-N 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- BWCSVQOHJHWHOD-UHFFFAOYSA-N 2-(2-anilinophenyl)-1-morpholin-4-ylethanethione Chemical compound N(C1=CC=CC=C1)C1=C(C=CC=C1)CC(=S)N1CCOCC1 BWCSVQOHJHWHOD-UHFFFAOYSA-N 0.000 abstract 1
- NJFCAWNKWPIBAG-UHFFFAOYSA-N 2-(2-anilinophenyl)acetic acid Chemical class OC(=O)CC1=CC=CC=C1NC1=CC=CC=C1 NJFCAWNKWPIBAG-UHFFFAOYSA-N 0.000 abstract 1
- DOXCWSBETLOACP-UHFFFAOYSA-N 2-anilinobenzoyl chloride Chemical class ClC(=O)C1=CC=CC=C1NC1=CC=CC=C1 DOXCWSBETLOACP-UHFFFAOYSA-N 0.000 abstract 1
- LZHUTAUPAKOTFY-UHFFFAOYSA-N CCO[Mg].CCOC(=O)CC(=O)OCC Chemical compound CCO[Mg].CCOC(=O)CC(=O)OCC LZHUTAUPAKOTFY-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 238000005672 Willgerodt-Kindler rearrangement reaction Methods 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- LJPIGDQQWFXJBF-UHFFFAOYSA-N diethyl 2-(2-anilinobenzoyl)propanedioate Chemical class C(C)OC(C(C(=O)OCC)C(C=1C(NC2=CC=CC=C2)=CC=CC=1)=O)=O LJPIGDQQWFXJBF-UHFFFAOYSA-N 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1451766A CH470349A (de) | 1966-10-07 | 1966-10-07 | Verfahren zur Herstellung von neuen substituierten Phenylessigsäuren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES345831A1 true ES345831A1 (es) | 1968-11-16 |
Family
ID=4401487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES345831A Expired ES345831A1 (es) | 1966-10-07 | 1967-10-06 | Procedimiento para la preparacion de nuevos acidos fenila- ceticos sustituidos. |
Country Status (12)
| Country | Link |
|---|---|
| AT (1) | AT273935B (es) |
| BE (1) | BE704820A (es) |
| CH (1) | CH470349A (es) |
| DK (1) | DK120243B (es) |
| ES (1) | ES345831A1 (es) |
| FI (1) | FI47880C (es) |
| GB (1) | GB1183968A (es) |
| GR (1) | GR37760B (es) |
| NL (1) | NL6713629A (es) |
| NO (1) | NO121047B (es) |
| SE (1) | SE345997B (es) |
| YU (1) | YU32369B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT370721B (de) * | 1981-02-24 | 1983-04-25 | Ciba Geigy Ag | Verfahren zur herstellung von neuen salzen der 2- (2,6-dichloranilino)-phenylessigsaeure, der |
| LU83138A1 (de) * | 1981-02-16 | 1981-09-11 | T Eckert | Topische pharmazeutische praeparate,enthaltend salze von alkancarbonsaeuren sowie neue carbonsaeuresalze und verfahren zu ihrer herstellung |
-
1966
- 1966-10-07 CH CH1451766A patent/CH470349A/de not_active IP Right Cessation
-
1967
- 1967-10-04 FI FI265567A patent/FI47880C/fi active
- 1967-10-06 DK DK497867A patent/DK120243B/da not_active IP Right Cessation
- 1967-10-06 ES ES345831A patent/ES345831A1/es not_active Expired
- 1967-10-06 SE SE1371067A patent/SE345997B/xx unknown
- 1967-10-06 GR GR670137760A patent/GR37760B/el unknown
- 1967-10-06 GB GB4572467A patent/GB1183968A/en not_active Expired
- 1967-10-06 AT AT910467A patent/AT273935B/de active
- 1967-10-06 NO NO17002467A patent/NO121047B/no unknown
- 1967-10-06 NL NL6713629A patent/NL6713629A/xx unknown
- 1967-10-06 YU YU194267A patent/YU32369B/xx unknown
- 1967-10-06 BE BE704820D patent/BE704820A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| YU32369B (en) | 1974-10-31 |
| GB1183968A (en) | 1970-03-11 |
| AT273935B (de) | 1969-08-25 |
| CH470349A (de) | 1969-03-31 |
| BE704820A (es) | 1968-04-08 |
| DK120243B (da) | 1971-05-03 |
| SE345997B (es) | 1972-06-19 |
| YU194267A (en) | 1974-04-30 |
| GR37760B (el) | 1969-07-12 |
| NO121047B (es) | 1971-01-11 |
| NL6713629A (es) | 1968-04-08 |
| FI47880B (es) | 1974-01-02 |
| FI47880C (fi) | 1974-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19860809 |