ES351702A1 - Parasiticidal Thionosalicylic Acid Anilides - Google Patents
Parasiticidal Thionosalicylic Acid AnilidesInfo
- Publication number
- ES351702A1 ES351702A1 ES351702A ES351702A ES351702A1 ES 351702 A1 ES351702 A1 ES 351702A1 ES 351702 A ES351702 A ES 351702A ES 351702 A ES351702 A ES 351702A ES 351702 A1 ES351702 A1 ES 351702A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- halogen
- nitro
- alkoxy
- signify
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title 1
- 229940051881 anilide analgesics and antipyretics Drugs 0.000 title 1
- 150000003931 anilides Chemical class 0.000 title 1
- 230000000590 parasiticidal effect Effects 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 241000242711 Fasciola hepatica Species 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 241000244206 Nematoda Species 0.000 abstract 1
- 241000869417 Trematodes Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 208000006275 fascioliasis Diseases 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- APFANDXNLZVWKT-UHFFFAOYSA-M potassium 2-aminoethanol hydroxide Chemical compound [OH-].[K+].NCCO APFANDXNLZVWKT-UHFFFAOYSA-M 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Pharmaceutical preparations suitable for combatting internal parasites, e.g. cestodes, nematodes, trematodes (particularly liver flukes), contain as active ingredient compounds of the general formula I '(including salts thereof wherein R is a hydrogen atom or an acyl radical, R, and R 2 signify hydrogen, alkyly or alkoxy (R 2 may also be halogen), R 3 , R 4 and R signify hydrogen. halogen, alkyl, hydroxy, alkoxy, nitro, haloalkyl, alkylmercapto or acyloxy and X and Y signify hydrogen, halogen or nitro and with the provisor that X and Y cannot in the same compound both be hydrogen and that when X is hydrogen Y can only be chlorine or bromine if each of the substituents R 3 , R 4 and R 5 is different from' the other two. Salts are those formed with bases such as sodium and potassium hydroxide ethanolamine, diethanolamine and piperazine. Alministration is orally, parenterally or subcutaneously, e.g. in the form of tablets, suppositories, pills, dragees, wrapped powders, cachets, sachets, capsules or ampoules.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0049138 | 1966-05-06 | ||
| DEF0049965 | 1966-08-17 | ||
| DEF0050110 | 1966-09-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES351702A1 true ES351702A1 (en) | 1969-06-16 |
Family
ID=27210481
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES340145A Expired ES340145A1 (en) | 1966-05-06 | 1967-05-05 | Parasiticidal Thionosalicylic Acid Anilides |
| ES351702A Expired ES351702A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
| ES351703A Expired ES351703A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
| ES351704A Expired ES351704A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
| ES351701A Expired ES351701A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
| ES351700A Expired ES351700A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES340145A Expired ES340145A1 (en) | 1966-05-06 | 1967-05-05 | Parasiticidal Thionosalicylic Acid Anilides |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES351703A Expired ES351703A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
| ES351704A Expired ES351704A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
| ES351701A Expired ES351701A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
| ES351700A Expired ES351700A1 (en) | 1966-05-06 | 1968-03-16 | Parasiticidal Thionosalicylic Acid Anilides |
Country Status (11)
| Country | Link |
|---|---|
| AT (1) | AT278840B (en) |
| BG (4) | BG15756A3 (en) |
| CH (4) | CH505134A (en) |
| DE (3) | DE1568522B1 (en) |
| DK (1) | DK124204B (en) |
| ES (6) | ES340145A1 (en) |
| FR (1) | FR1522005A (en) |
| GB (2) | GB1164017A (en) |
| IL (2) | IL36414A (en) |
| NL (1) | NL155254B (en) |
| SE (5) | SE364264B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1805156B2 (en) * | 1968-10-25 | 1976-01-29 | Bayer Ag, 5090 Leverkusen | PROCESS FOR THE PREPARATION OF 2-ACYLOXYTHIONOBENZAMIDES |
| JPS63313780A (en) * | 1987-04-14 | 1988-12-21 | ユニロイヤル ケミカル カンパニー インコーポレーテツド | Substituted benzoxazinone compound, manufacture and agricultural drug |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1045717B (en) * | 1956-07-06 | 1958-12-04 | Bayer Ag | Gastropod control agents |
-
1966
- 1966-05-06 DE DE19661568522D patent/DE1568522B1/en active Pending
- 1966-08-17 DE DE19661670733 patent/DE1670733A1/en active Pending
- 1966-09-03 DE DE19661568577 patent/DE1568577A1/en active Pending
-
1967
- 1967-04-10 CH CH1652169A patent/CH505134A/en not_active IP Right Cessation
- 1967-04-10 CH CH1652069A patent/CH503002A/en not_active IP Right Cessation
- 1967-04-10 CH CH505167A patent/CH493496A/en not_active IP Right Cessation
- 1967-04-10 CH CH1651969A patent/CH505078A/en not_active IP Right Cessation
- 1967-04-18 IL IL36414A patent/IL36414A/en unknown
- 1967-04-18 IL IL27811A patent/IL27811A/en unknown
- 1967-04-22 BG BG010487A patent/BG15756A3/en unknown
- 1967-04-22 BG BG010490A patent/BG15758A3/en unknown
- 1967-04-22 BG BG010489A patent/BG18418A3/en unknown
- 1967-04-22 BG BG010488A patent/BG15757A3/en unknown
- 1967-04-24 SE SE05757/67A patent/SE364264B/xx unknown
- 1967-04-24 SE SE07678/69A patent/SE364265B/xx unknown
- 1967-04-24 SE SE07676/69A patent/SE364042B/xx unknown
- 1967-04-24 SE SE07675/69A patent/SE364041B/xx unknown
- 1967-05-01 GB GB56732/68A patent/GB1164017A/en not_active Expired
- 1967-05-01 GB GB20013/67A patent/GB1164016A/en not_active Expired
- 1967-05-05 NL NL676706356A patent/NL155254B/en not_active IP Right Cessation
- 1967-05-05 AT AT09061/68A patent/AT278840B/en not_active IP Right Cessation
- 1967-05-05 ES ES340145A patent/ES340145A1/en not_active Expired
- 1967-05-05 FR FR105457A patent/FR1522005A/en not_active Expired
-
1968
- 1968-03-16 ES ES351702A patent/ES351702A1/en not_active Expired
- 1968-03-16 ES ES351703A patent/ES351703A1/en not_active Expired
- 1968-03-16 ES ES351704A patent/ES351704A1/en not_active Expired
- 1968-03-16 ES ES351701A patent/ES351701A1/en not_active Expired
- 1968-03-16 ES ES351700A patent/ES351700A1/en not_active Expired
-
1969
- 1969-05-30 SE SE7677/69A patent/SE345461B/xx unknown
- 1969-12-10 DK DK655169AA patent/DK124204B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG18418A3 (en) | 1974-10-25 |
| GB1164017A (en) | 1969-09-10 |
| NL155254B (en) | 1977-12-15 |
| IL27811A (en) | 1971-07-28 |
| BG15758A3 (en) | 1976-08-25 |
| IL36414A (en) | 1971-10-20 |
| DE1568577A1 (en) | 1970-03-19 |
| BG15756A3 (en) | 1976-06-26 |
| SE364264B (en) | 1974-02-18 |
| FR1522005A (en) | 1968-04-19 |
| CH503002A (en) | 1971-02-15 |
| ES340145A1 (en) | 1968-09-01 |
| ES351703A1 (en) | 1969-06-16 |
| SE345461B (en) | 1972-05-29 |
| SE364041B (en) | 1974-02-11 |
| CH505078A (en) | 1971-03-31 |
| CH493496A (en) | 1970-07-15 |
| SE364265B (en) | 1974-02-18 |
| ES351701A1 (en) | 1969-06-16 |
| DE1670733A1 (en) | 1970-12-23 |
| BG15757A3 (en) | 1976-06-25 |
| DE1568522B1 (en) | 1970-11-12 |
| GB1164016A (en) | 1969-09-10 |
| SE364042B (en) | 1974-02-11 |
| AT278840B (en) | 1970-02-10 |
| DK124204B (en) | 1972-09-25 |
| ES351704A1 (en) | 1969-07-16 |
| NL6706356A (en) | 1967-11-07 |
| ES351700A1 (en) | 1969-06-16 |
| CH505134A (en) | 1971-03-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1334138A (en) | Immunological adjuvatns | |
| SE340459B (en) | ||
| ES336020A1 (en) | Procedure for the preparation of new derivatives of imidazol. (Machine-translation by Google Translate, not legally binding) | |
| ES340145A1 (en) | Parasiticidal Thionosalicylic Acid Anilides | |
| ES340221A1 (en) | N-(hydroxy-cyclohexyl)-aminobenzylamines and the salts thereof | |
| GB1023793A (en) | The manufacture of benzodiazepine derivatives | |
| ES368908A1 (en) | A PROCEDURE FOR THE PREPARATION OF IMDAZOLIDINOQUINA-ZOLINAS. | |
| IE34665L (en) | Isothioureas | |
| GB1154547A (en) | Substituted Benzylamines | |
| GB1061306A (en) | 4-substituted-2-benzhydryl-2-butanol derivatives | |
| GB1185045A (en) | Amine Derivatives | |
| GB1454864A (en) | Thioureas | |
| ES314360A1 (en) | A procedure for the elaboration of sulfonamides of the pirimidinicas series. (Machine-translation by Google Translate, not legally binding) | |
| GB1195319A (en) | Alkyl Sulfate Salts of 1-(p-Chlorobenzhydryl)-4-Methylhomopiperazines | |
| IE33915B1 (en) | Phenethyl alcohols | |
| GB1391052A (en) | Medicinal use of pyrazolone derivatives | |
| GB1055741A (en) | Pharmaceutical compositions comprising substituted urea derivatives | |
| GB1252815A (en) | ||
| GB1034872A (en) | Benzodiazepine derivatives | |
| GB1025577A (en) | Benzdiaz[1,4]epine derivatives and the manufacture thereof | |
| GB1159748A (en) | Thiol-Type Thiamine Thionocarbonates | |
| GB935860A (en) | Unsaturated new sulphonamides | |
| HU9301498D0 (en) | Pharmaceutical preparatives containing sulfonamides, new sulfonamides and method for producing them | |
| GB1152677A (en) | Improved Anabolic Agent | |
| GB1157632A (en) | Therapeutic Compositions comprising 1-Arylthiocarbamyl-Imidazolidine-2-Thiones |