ES351960A1 - Preparation of a Sulphur-Containing Pyridine Derivative - Google Patents
Preparation of a Sulphur-Containing Pyridine DerivativeInfo
- Publication number
- ES351960A1 ES351960A1 ES351960A ES351960A ES351960A1 ES 351960 A1 ES351960 A1 ES 351960A1 ES 351960 A ES351960 A ES 351960A ES 351960 A ES351960 A ES 351960A ES 351960 A1 ES351960 A1 ES 351960A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- preparation
- sulphur
- hydrogen
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003222 pyridines Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001118 alkylidene group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
A process for the preparation of compound I herein and its salts, which comprises treating a compound of the Formula II in which R 1 and R 2 , which may be the same or different, are hydrogen or acyl groups or together form the divalent radical R 3 and R 4 , which may be the same or different, are hydrogen or alkyl groups containing up to 5 carbon atoms or together form an alkylidene group containing up to 5 carbon atoms or, together with the carbon atoms to which they are attached, form a 5- or 6-membered hydrocarbon ring, and m is an alkali metal, with an acidic medium and then adjusting the reaction mixture to a neutral, weakly acidic or weakly alkaline pH and, if desired, converting the product of Formula I obtained to an acid addition or quaternary ammonium salt thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEM0073338 | 1967-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES351960A1 true ES351960A1 (en) | 1969-06-01 |
Family
ID=7314979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES351960A Expired ES351960A1 (en) | 1967-03-25 | 1968-03-23 | Preparation of a Sulphur-Containing Pyridine Derivative |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE711087A (en) |
| CH (1) | CH494759A (en) |
| CS (1) | CS150572B2 (en) |
| ES (1) | ES351960A1 (en) |
| FR (1) | FR1568119A (en) |
| GB (1) | GB1153555A (en) |
| IL (1) | IL29534A (en) |
| NL (1) | NL151074B (en) |
| SE (1) | SE336791B (en) |
| YU (1) | YU32925B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100509787C (en) * | 2006-01-20 | 2009-07-08 | 山东轩竹医药科技有限公司 | New pharmaceutically acceptable salt of pyritinol, and a preparation method thereof |
-
1968
- 1968-02-12 CH CH202068A patent/CH494759A/en not_active IP Right Cessation
- 1968-02-13 FR FR1568119D patent/FR1568119A/fr not_active Expired
- 1968-02-13 GB GB712568A patent/GB1153555A/en not_active Expired
- 1968-02-19 NL NL6802320A patent/NL151074B/en unknown
- 1968-02-21 BE BE711087D patent/BE711087A/xx unknown
- 1968-02-27 IL IL2953468A patent/IL29534A/en unknown
- 1968-03-01 CS CS165168A patent/CS150572B2/cs unknown
- 1968-03-04 YU YU49468A patent/YU32925B/en unknown
- 1968-03-21 SE SE375568A patent/SE336791B/xx unknown
- 1968-03-23 ES ES351960A patent/ES351960A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE711087A (en) | 1968-07-01 |
| IL29534A (en) | 1971-07-28 |
| CS150572B2 (en) | 1973-09-04 |
| YU32925B (en) | 1975-12-31 |
| CH494759A (en) | 1970-08-15 |
| DE1695402A1 (en) | 1971-03-18 |
| DE1695402B2 (en) | 1975-07-24 |
| SE336791B (en) | 1971-07-19 |
| NL6802320A (en) | 1968-09-26 |
| NL151074B (en) | 1976-10-15 |
| GB1153555A (en) | 1969-05-29 |
| FR1568119A (en) | 1969-05-23 |
| YU49468A (en) | 1975-06-30 |
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