ES353213A1 - Procedimiento para la produccion de derivados de dibenzo- tiazepina. - Google Patents
Procedimiento para la produccion de derivados de dibenzo- tiazepina.Info
- Publication number
- ES353213A1 ES353213A1 ES353213A ES353213A ES353213A1 ES 353213 A1 ES353213 A1 ES 353213A1 ES 353213 A ES353213 A ES 353213A ES 353213 A ES353213 A ES 353213A ES 353213 A1 ES353213 A1 ES 353213A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- hydrogen
- alkyl
- haloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008509 dibenzothiazepines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000001188 haloalkyl group Chemical group 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- NJZMXHPPLVFYHA-UHFFFAOYSA-N 11-methyl-6h-benzo[c][1,5]benzothiazepine Chemical compound C1SC2=CC=CC=C2N(C)C2=CC=CC=C21 NJZMXHPPLVFYHA-UHFFFAOYSA-N 0.000 abstract 1
- KOQNCVXJKCNFNN-UHFFFAOYSA-N 6-(3-chloropropyl)-11-methyl-6H-benzo[c][1,5]benzothiazepine Chemical compound CN1C2=C(SC(C3=C1C=CC=C3)CCCCl)C=CC=C2 KOQNCVXJKCNFNN-UHFFFAOYSA-N 0.000 abstract 1
- MFESCIUQSIBMSM-UHFFFAOYSA-N I-BCP Chemical compound ClCCCBr MFESCIUQSIBMSM-UHFFFAOYSA-N 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000002642 lithium compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- NHKJPPKXDNZFBJ-UHFFFAOYSA-N phenyllithium Chemical compound [Li]C1=CC=CC=C1 NHKJPPKXDNZFBJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/14—[b, e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2762567 | 1967-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES353213A1 true ES353213A1 (es) | 1969-10-01 |
Family
ID=12226117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES353213A Expired ES353213A1 (es) | 1967-04-28 | 1968-04-26 | Procedimiento para la produccion de derivados de dibenzo- tiazepina. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3625974A (es) |
| CH (1) | CH518301A (es) |
| DE (1) | DE1770242C3 (es) |
| ES (1) | ES353213A1 (es) |
| FR (1) | FR7638M (es) |
| GB (1) | GB1213172A (es) |
| SE (1) | SE366047B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA918659A (en) * | 1969-07-31 | 1973-01-09 | Yoshitomi Pharmaceutical Industries | 11-(4-substituted-1-piperazinyl)-dibenzo (b,f) (1,4) thiazepines |
| US4500472A (en) * | 1981-05-11 | 1985-02-19 | Ciba-Geigy Corporation | Process for preparing imidazobenzothiadiazepines |
| US6323206B1 (en) | 1996-07-12 | 2001-11-27 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6509346B2 (en) | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6613905B1 (en) | 1998-01-21 | 2003-09-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| AU2331999A (en) | 1998-01-21 | 1999-08-09 | Kyowa Hakko Kogyo Co. Ltd. | Chemokine receptor antagonists and methods of use therefor |
| CA2318088A1 (en) | 1998-01-21 | 1999-07-29 | Yoshisuke Nakasato | Chemokine receptor antagonists and methods of use therefor |
| US7271176B2 (en) | 1998-09-04 | 2007-09-18 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use thereof |
| US7541365B2 (en) | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3188322A (en) * | 1962-08-08 | 1965-06-08 | Olin Mathieson | Dihydrodibenzothiazepines |
-
1968
- 1968-04-18 US US722169A patent/US3625974A/en not_active Expired - Lifetime
- 1968-04-20 DE DE1770242A patent/DE1770242C3/de not_active Expired
- 1968-04-22 GB GB08954/68A patent/GB1213172A/en not_active Expired
- 1968-04-23 SE SE05450/68A patent/SE366047B/xx unknown
- 1968-04-26 FR FR149715A patent/FR7638M/fr not_active Expired
- 1968-04-26 CH CH625468A patent/CH518301A/de not_active IP Right Cessation
- 1968-04-26 ES ES353213A patent/ES353213A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1770242B2 (de) | 1978-09-14 |
| SE366047B (es) | 1974-04-08 |
| GB1213172A (en) | 1970-11-18 |
| FR7638M (es) | 1970-02-02 |
| CH518301A (de) | 1972-01-31 |
| US3625974A (en) | 1971-12-07 |
| DE1770242C3 (de) | 1979-05-03 |
| DE1770242A1 (de) | 1971-10-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES353213A1 (es) | Procedimiento para la produccion de derivados de dibenzo- tiazepina. | |
| GB1120463A (en) | Derivatives of 1,3-diazafluoranthene-1-oxide | |
| GB1106040A (en) | Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof | |
| GB1111989A (en) | 2',3'-dideoxyriboside-2',3'-olefins | |
| CH611615A5 (en) | Process for the preparation of novel indole derivatives | |
| ZA818934B (en) | Trisubstituted pyrimido pyrimidines,processes for their preparation,and pharmaceutical compositions thereof | |
| GB1456627A (en) | Pyridobenzodiazepinones | |
| GB1023793A (en) | The manufacture of benzodiazepine derivatives | |
| GB1069797A (en) | ª-aminoketone derivatives | |
| GB1086338A (en) | Basically substituted derivatives of 5,6-dihydro-dibenzo-[b,e]-azepine-6,11-dione-11-oxime | |
| GB1023205A (en) | -triazino(5,6-6) indoles | |
| ES428673A1 (es) | Procedimiento para la obtencion de derivados de nitrobenzo-fenona sustituidos. | |
| GB1218590A (en) | N-substituted piperidine spiro compounds | |
| GB1085135A (en) | Aryl-ª-aminoketone derivatives | |
| GB1043853A (en) | Improvements in or relating to diphenylsulphide compounds | |
| GB1245155A (en) | NOVEL 5-SUBSTITUTED-gamma-CARBOLINE DERIVATIVES AND THE SALTS THEREOF | |
| GB2001062A (en) | Preparation of Pyridinecarboxylic acid piperazides | |
| ES8307233A1 (es) | Procedimiento para preparar derivados del acido 1,4-tiazan-3-carboxilico. | |
| GB992731A (en) | Aminoalkyl-indolyl-benzyl alcohols | |
| GB1114694A (en) | Diazaspiro[4,5]decan-1,3-dione derivatives | |
| GB1172341A (en) | Oxazine Derivatives | |
| GB956616A (en) | New substituted diphenylalkylamines | |
| GB1421058A (en) | Dibenzocycloheptenyl lactamimides | |
| GB1115327A (en) | Dibenzocycloheptene derivatives | |
| GB1420758A (en) | Anti-ulcer compositions |