ES357216A2 - Procedimiento para la preparacion de derivados de isoindol - Google Patents
Procedimiento para la preparacion de derivados de isoindolInfo
- Publication number
- ES357216A2 ES357216A2 ES357216A ES357216A ES357216A2 ES 357216 A2 ES357216 A2 ES 357216A2 ES 357216 A ES357216 A ES 357216A ES 357216 A ES357216 A ES 357216A ES 357216 A2 ES357216 A2 ES 357216A2
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- chlorine
- fluorine atom
- formula
- meaning
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VHMICKWLTGFITH-UHFFFAOYSA-N 2H-isoindole Chemical class C1=CC=CC2=CNC=C21 VHMICKWLTGFITH-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 8
- 229910052739 hydrogen Inorganic materials 0.000 abstract 8
- 229910052801 chlorine Inorganic materials 0.000 abstract 5
- 239000000460 chlorine Substances 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052731 fluorine Inorganic materials 0.000 abstract 4
- 125000001153 fluoro group Chemical group F* 0.000 abstract 4
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 3
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical compound F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 3
- -1 alkyl radical Chemical class 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- QKDLQFSLLCQTOH-UHFFFAOYSA-N Trichodonin Natural products C1C(O)C2C3(COC(=O)C)C(C=O)C(C)(C)CCC3OC(=O)C22C(=O)C(=C)C1C2 QKDLQFSLLCQTOH-UHFFFAOYSA-N 0.000 abstract 1
- 239000012298 atmosphere Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 239000012299 nitrogen atmosphere Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
- C07C51/21—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen
- C07C51/23—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups
- C07C51/245—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups of keto groups or secondary alcohol groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/34—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62529967A | 1967-03-23 | 1967-03-23 | |
| ES351834A ES351834A1 (es) | 1967-03-23 | 1968-03-21 | Procedimiento para la preparacion de derivados de isoindol. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES357216A2 true ES357216A2 (es) | 1971-01-16 |
Family
ID=24505431
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES351834A Expired ES351834A1 (es) | 1967-03-23 | 1968-03-21 | Procedimiento para la preparacion de derivados de isoindol. |
| ES357216A Expired ES357216A2 (es) | 1967-03-23 | 1968-08-13 | Procedimiento para la preparacion de derivados de isoindol |
| ES368450A Expired ES368450A2 (es) | 1967-03-23 | 1969-06-17 | Procedimiento para la preparacion de derivados de isoindol. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES351834A Expired ES351834A1 (es) | 1967-03-23 | 1968-03-21 | Procedimiento para la preparacion de derivados de isoindol. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES368450A Expired ES368450A2 (es) | 1967-03-23 | 1969-06-17 | Procedimiento para la preparacion de derivados de isoindol. |
Country Status (12)
| Country | Link |
|---|---|
| AT (1) | AT299187B (es) |
| BE (1) | BE712596A (es) |
| DE (2) | DE1770030A1 (es) |
| DK (1) | DK136117B (es) |
| ES (3) | ES351834A1 (es) |
| FI (1) | FI48840C (es) |
| FR (1) | FR7623M (es) |
| GB (1) | GB1225411A (es) |
| MY (1) | MY7300316A (es) |
| NL (1) | NL6803799A (es) |
| NO (1) | NO130826C (es) |
| SE (1) | SE335349B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1770009C2 (de) * | 1968-03-20 | 1987-04-16 | American Home Products Corp., New York, N.Y. | Verfahren zur Herstellung von Imidazolinyl-Verbindungen |
| CH531511A (de) * | 1969-03-05 | 1972-12-15 | Sandoz Ag | Verfahren zur Herstellung des N,o-Dilithium-Derivats von 2-Phenyl-2-imidazolin |
| US4200759A (en) * | 1978-07-20 | 1980-04-29 | Delmar Chemicals, Limited | Preparation of imidazo[2,1-a]isoindole compounds |
| DE19720859A1 (de) * | 1997-05-13 | 1998-11-19 | Inst Chemo Biosensorik | Vorrichtung zum schnellen elektrischen Verbinden einer Sensoranordnung mit einem Meßgerät |
-
1968
- 1968-03-18 NL NL6803799A patent/NL6803799A/xx unknown
- 1968-03-21 BE BE712596D patent/BE712596A/xx not_active IP Right Cessation
- 1968-03-21 ES ES351834A patent/ES351834A1/es not_active Expired
- 1968-03-21 AT AT283568A patent/AT299187B/de active
- 1968-03-22 FI FI680807A patent/FI48840C/fi active
- 1968-03-22 GB GB1225411D patent/GB1225411A/en not_active Expired
- 1968-03-22 DE DE19681770030 patent/DE1770030A1/de active Pending
- 1968-03-22 DE DE19681795758 patent/DE1795758A1/de active Pending
- 1968-03-22 SE SE03840/68A patent/SE335349B/xx unknown
- 1968-03-22 DK DK126068AA patent/DK136117B/da not_active IP Right Cessation
- 1968-06-18 FR FR155413A patent/FR7623M/fr not_active Expired
- 1968-08-13 ES ES357216A patent/ES357216A2/es not_active Expired
-
1969
- 1969-06-17 ES ES368450A patent/ES368450A2/es not_active Expired
-
1972
- 1972-09-27 NO NO723452A patent/NO130826C/no unknown
-
1973
- 1973-12-30 MY MY316/73A patent/MY7300316A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI48840C (fi) | 1975-01-10 |
| DE1770030A1 (de) | 1971-09-23 |
| AT299187B (de) | 1972-06-12 |
| NL6803799A (es) | 1968-09-24 |
| SE335349B (es) | 1971-05-24 |
| MY7300316A (en) | 1973-12-31 |
| DE1795758A1 (de) | 1974-10-10 |
| NO130826C (es) | 1975-02-19 |
| BE712596A (es) | 1968-09-23 |
| FI48840B (es) | 1974-09-30 |
| GB1225411A (es) | 1971-03-17 |
| DK136117C (es) | 1978-01-16 |
| FR7623M (es) | 1970-01-26 |
| DK136117B (da) | 1977-08-15 |
| ES368450A2 (es) | 1971-07-16 |
| ES351834A1 (es) | 1969-12-01 |
| NO130826B (es) | 1974-11-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES380041A1 (es) | Procedimiento para la obtencion de derivados de quinazoli- nona. | |
| ES378367A1 (es) | Procedimiento para la preparacion de nucleosidos. | |
| RO70893B (ro) | Procedeu pentru prepararea azinelor | |
| ES357216A2 (es) | Procedimiento para la preparacion de derivados de isoindol | |
| ES376661A1 (es) | Procedimiento para la obtencion de derivados de acetil-gua-nidina. | |
| ES454824A1 (es) | Procedimiento para la preparacion de derivados de imidazo (1,2-a) piridina. | |
| ES458381A1 (es) | Procedimiento para la preparacion de 1.2.6-tiadiazinonas. | |
| ES386121A1 (es) | Procedimiento para la obtencion de derivados de 4-amino- quinazolina. | |
| ES324510A1 (es) | Procedimiento para la polimerizacion de compuestos organicos no saturados. | |
| ES436742A1 (es) | Procedimiento para la preparacion de aceites cosmeticos protectores frente a la luz. | |
| ES335708A1 (es) | Procedimiento para la preparacion de derivados de la isoindolo-benzodiacepin-6-ona. | |
| ES456048A1 (es) | Procedimiento de preparacion de derivados de la piridoxina. | |
| ES386567A1 (es) | Procedimiento para la obtencion de derivados de piridazona. | |
| ES474955A1 (es) | Un procedimiento para la preparacion de un compuesto polici-clico | |
| JPS5242292A (en) | Base and spacer for communication and power cable or conduit | |
| ES477430A1 (es) | Un procedimiento para la preparacion de 5'8-dihidro-6,6,8- trimetil-5'8-etano-6h-pirano(4,3-e)-as-triacinas y sus 4 o- xidos. | |
| ES379160A1 (es) | Procedimiento para la obtencion de derivados del 4-metil - 2 - nitrobenzonitrilo. | |
| ES404833A1 (es) | Procedimiento para la obtencion de derivados de la quinazo-linona. | |
| ES345217A1 (es) | Procedimiento para la preparacion de compuestos derivados del alcohol bencilico. | |
| ES434406A1 (es) | Procedimiento para preparar derivados de naftiridina. | |
| ES396873A1 (es) | Procedimiento para la obtencion de derivados de piridaci- na. | |
| ES338206A1 (es) | Procedimiento para la produccion de derivados de urea sul- fonilica. | |
| ES326147A1 (es) | Procedimiento para la obtencion de derivados de la benzodiacepin-2-ona. | |
| ES313761A1 (es) | Procedimiento para la obtencion de derivados del acido ergolenil(8)-hidroxamido. | |
| ES428968A1 (es) | Procedimiento para la preparacion de 1, 2, 2, 2-tetrafluo- raltil-eteres. |