ES358828A1 - Procedimiento para la preparacion de un nuevo acido arilo- xialcano y sus sales. - Google Patents
Procedimiento para la preparacion de un nuevo acido arilo- xialcano y sus sales.Info
- Publication number
- ES358828A1 ES358828A1 ES358828A ES358828A ES358828A1 ES 358828 A1 ES358828 A1 ES 358828A1 ES 358828 A ES358828 A ES 358828A ES 358828 A ES358828 A ES 358828A ES 358828 A1 ES358828 A1 ES 358828A1
- Authority
- ES
- Spain
- Prior art keywords
- pentyl
- prepared
- biphenylyloxy
- acid
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 5
- 239000002253 acid Substances 0.000 title abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 4
- -1 alkali metal salt Chemical class 0.000 abstract 4
- 229910052708 sodium Inorganic materials 0.000 abstract 4
- 239000011734 sodium Substances 0.000 abstract 4
- 239000000543 intermediate Substances 0.000 abstract 3
- RGMMREBHCYXQMA-UHFFFAOYSA-N 2-hydroxyheptanoic acid Chemical compound CCCCCC(O)C(O)=O RGMMREBHCYXQMA-UHFFFAOYSA-N 0.000 abstract 2
- WEAFBPWCYVGTAB-UHFFFAOYSA-N 2-(4-phenylphenoxy)heptanoic acid Chemical compound C1=CC(OC(CCCCC)C(O)=O)=CC=C1C1=CC=CC=C1 WEAFBPWCYVGTAB-UHFFFAOYSA-N 0.000 abstract 1
- YVTMVUAFKLSFJY-UHFFFAOYSA-N 2-cyano-2-(4-phenylphenoxy)heptanoic acid Chemical compound C1(=CC=C(C=C1)OC(C(=O)O)(C#N)CCCCC)C1=CC=CC=C1 YVTMVUAFKLSFJY-UHFFFAOYSA-N 0.000 abstract 1
- YRKANMSVJZVSLB-UHFFFAOYSA-N 2-pentyl-2-(4-phenylphenoxy)propanedioic acid Chemical compound C1(=CC=C(C=C1)OC(C(=O)O)(C(=O)O)CCCCC)C1=CC=CC=C1 YRKANMSVJZVSLB-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- YXVFYQXJAXKLAK-UHFFFAOYSA-N biphenyl-4-ol Chemical compound C1=CC(O)=CC=C1C1=CC=CC=C1 YXVFYQXJAXKLAK-UHFFFAOYSA-N 0.000 abstract 1
- 230000031709 bromination Effects 0.000 abstract 1
- 238000005893 bromination reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 230000000911 decarboxylating effect Effects 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- PSOUETBRCHLRNY-UHFFFAOYSA-N diethyl 2-bromo-2-pentylpropanedioate Chemical compound CCCCCC(Br)(C(=O)OCC)C(=O)OCC PSOUETBRCHLRNY-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- VRCFFPJTGBDVAA-UHFFFAOYSA-N ethyl 2-(4-phenylphenoxy)heptanoate Chemical compound C(C)OC(C(CCCCC)OC1=CC=C(C=C1)C1=CC=CC=C1)=O VRCFFPJTGBDVAA-UHFFFAOYSA-N 0.000 abstract 1
- HONATTAEGBOECL-UHFFFAOYSA-N ethyl 2-cyano-2-(4-phenylphenoxy)heptanoate Chemical compound C1(=CC=C(C=C1)OC(C(=O)OCC)(C#N)CCCCC)C1=CC=CC=C1 HONATTAEGBOECL-UHFFFAOYSA-N 0.000 abstract 1
- ZIUSEGSNTOUIPT-UHFFFAOYSA-N ethyl 2-cyanoacetate Chemical compound CCOC(=O)CC#N ZIUSEGSNTOUIPT-UHFFFAOYSA-N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000000055 hyoplipidemic effect Effects 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/06—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1402967A CH501575A (de) | 1967-10-06 | 1967-10-06 | Verfahren zur Herstellung einer neuen Aryloxyalkansäure und ihrer Salze |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES358828A1 true ES358828A1 (es) | 1970-06-01 |
Family
ID=4397336
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES358828A Expired ES358828A1 (es) | 1967-10-06 | 1968-10-04 | Procedimiento para la preparacion de un nuevo acido arilo- xialcano y sus sales. |
| ES358825A Expired ES358825A1 (es) | 1967-10-06 | 1968-10-04 | Procedimiento para la preparacion de un nuevo acido arilo- xialcanico y sus sales. |
| ES358827A Expired ES358827A1 (es) | 1967-10-06 | 1968-10-04 | Procedimiento para la preparacion de un nuevo acido arolo- xialcano y sus sales. |
| ES358826A Expired ES358826A1 (es) | 1967-10-06 | 1968-10-04 | Procedimiento para la preparacion de un nuevo acido arilo- xialcano y sus sales. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES358825A Expired ES358825A1 (es) | 1967-10-06 | 1968-10-04 | Procedimiento para la preparacion de un nuevo acido arilo- xialcanico y sus sales. |
| ES358827A Expired ES358827A1 (es) | 1967-10-06 | 1968-10-04 | Procedimiento para la preparacion de un nuevo acido arolo- xialcano y sus sales. |
| ES358826A Expired ES358826A1 (es) | 1967-10-06 | 1968-10-04 | Procedimiento para la preparacion de un nuevo acido arilo- xialcano y sus sales. |
Country Status (10)
| Country | Link |
|---|---|
| AT (3) | AT282604B (fr) |
| BE (1) | BE721973A (fr) |
| BR (1) | BR6802881D0 (fr) |
| CH (2) | CH542806A (fr) |
| DE (1) | DE1801312A1 (fr) |
| ES (4) | ES358828A1 (fr) |
| FR (2) | FR1596597A (fr) |
| GB (1) | GB1249492A (fr) |
| IL (1) | IL30817A0 (fr) |
| NL (1) | NL6813908A (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5252252A (en) * | 1983-09-10 | 1993-10-12 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Anisotropic compounds and liquid crystal mixtures |
| DE3332692A1 (de) * | 1983-09-10 | 1985-03-28 | Merck Patent Gmbh, 6100 Darmstadt | Anisotrope verbindungen und fluessigkristallmischungen |
| BRPI0409914A (pt) * | 2003-04-30 | 2006-04-25 | Inst For Pharm Discovery Inc | ácidos carboxìlicos substituìdos |
| WO2008033931A1 (fr) * | 2006-09-13 | 2008-03-20 | The Institutes For Pharmaceutical Discovery, Llc | Acides carboxyliques de para-xylylène et isothiazolones utiles comme protéines tyrosine phosphatases (ptps) en particulier ptp-ib |
-
1967
- 1967-10-06 CH CH239570A patent/CH542806A/de not_active IP Right Cessation
- 1967-10-06 CH CH1402967A patent/CH501575A/de not_active IP Right Cessation
-
1968
- 1968-09-27 NL NL6813908A patent/NL6813908A/xx unknown
- 1968-10-04 BR BR202881/68A patent/BR6802881D0/pt unknown
- 1968-10-04 GB GB47167/68A patent/GB1249492A/en not_active Expired
- 1968-10-04 AT AT968268A patent/AT282604B/de not_active IP Right Cessation
- 1968-10-04 IL IL30817A patent/IL30817A0/xx unknown
- 1968-10-04 AT AT764869A patent/AT282607B/de not_active IP Right Cessation
- 1968-10-04 AT AT765069A patent/AT282608B/de not_active IP Right Cessation
- 1968-10-04 ES ES358828A patent/ES358828A1/es not_active Expired
- 1968-10-04 ES ES358825A patent/ES358825A1/es not_active Expired
- 1968-10-04 ES ES358827A patent/ES358827A1/es not_active Expired
- 1968-10-04 ES ES358826A patent/ES358826A1/es not_active Expired
- 1968-10-04 DE DE19681801312 patent/DE1801312A1/de active Pending
- 1968-10-07 BE BE721973D patent/BE721973A/xx unknown
- 1968-10-07 FR FR1596597D patent/FR1596597A/fr not_active Expired
-
1969
- 1969-01-03 FR FR183176A patent/FR8267M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH542806A (de) | 1973-10-15 |
| AT282604B (de) | 1970-07-10 |
| BR6802881D0 (pt) | 1973-02-22 |
| AT282608B (de) | 1970-07-10 |
| ES358826A1 (es) | 1970-06-01 |
| FR1596597A (fr) | 1970-06-22 |
| ES358825A1 (es) | 1970-06-01 |
| DE1801312A1 (de) | 1969-05-08 |
| FR8267M (fr) | 1970-10-26 |
| IL30817A0 (en) | 1968-12-26 |
| NL6813908A (fr) | 1969-04-09 |
| GB1249492A (en) | 1971-10-13 |
| CH501575A (de) | 1971-01-15 |
| BE721973A (fr) | 1969-04-08 |
| ES358827A1 (es) | 1970-06-01 |
| AT282607B (de) | 1970-07-10 |
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