ES359021A1 - Preparation procedure of 17-oxygenated-3-etoxy-6- (a- minometil-disused) pregna-3,5-dien-20-onas. (Machine-translation by Google Translate, not legally binding) - Google Patents
Preparation procedure of 17-oxygenated-3-etoxy-6- (a- minometil-disused) pregna-3,5-dien-20-onas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES359021A1 ES359021A1 ES359021A ES359021A ES359021A1 ES 359021 A1 ES359021 A1 ES 359021A1 ES 359021 A ES359021 A ES 359021A ES 359021 A ES359021 A ES 359021A ES 359021 A1 ES359021 A1 ES 359021A1
- Authority
- ES
- Spain
- Prior art keywords
- pregna
- dien
- translation
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- CPUKWYXYHPOQJH-RDQPJNLGSA-N (8r,9s,10s,13s,14s)-17-ethenyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1h-cyclopenta[a]phenanthrene Chemical compound C1CCC[C@]2(C)[C@H]3CC[C@](C)(C(=CC4)C=C)[C@@H]4[C@@H]3CCC21 CPUKWYXYHPOQJH-RDQPJNLGSA-N 0.000 abstract 1
- YXRFQWKNFFQPAQ-LEKSSAKUSA-N 1-[(8s,9s,10r,13s,14s,17s)-10,13-dimethyl-2,7,8,9,11,12,14,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-17-yl]ethanone Chemical class C1C=C2C=CCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 YXRFQWKNFFQPAQ-LEKSSAKUSA-N 0.000 abstract 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- TUCNEACPLKLKNU-UHFFFAOYSA-N acetyl Chemical compound C[C]=O TUCNEACPLKLKNU-UHFFFAOYSA-N 0.000 abstract 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910001882 dioxygen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical class [H]N([H])* 0.000 abstract 1
- 238000006268 reductive amination reaction Methods 0.000 abstract 1
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Preparation process of 17-oxygenate-3-ethoxy-6- (aminomethyl-disubstituted) pregna-3,5-dien-20-ones, of general formula, ** (see formula) ** Wherein r and r'can be alkyl, alkanoyl or alkanoylalkylene radicals, x' can be a hydrogen atom or a chloro, fluoro or acetoxy substituent, r "is acetyl when x'is a chloro or fluoro substituent: r''is hydrogen or an acetyl radical when x' is an acetoxy group and r "may also be acetyl when x'is hydrogen and r and r' are non-identical functions, characterized in that it comprises the reductive amination of a compound of general formula, ** (see formula) ** Wherein r "and x'are as defined above, employing a primary amine and molecular oxygen in the presence of a hydrogenation catalyst, to produce the corresponding 6 - [- (monosubstituted) -amino-methyl] pregnadiene. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES359021A ES359021A1 (en) | 1968-10-10 | 1968-10-10 | Preparation procedure of 17-oxygenated-3-etoxy-6- (a- minometil-disused) pregna-3,5-dien-20-onas. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES359021A ES359021A1 (en) | 1968-10-10 | 1968-10-10 | Preparation procedure of 17-oxygenated-3-etoxy-6- (a- minometil-disused) pregna-3,5-dien-20-onas. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES359021A1 true ES359021A1 (en) | 1970-05-16 |
Family
ID=8450592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES359021A Expired ES359021A1 (en) | 1968-10-10 | 1968-10-10 | Preparation procedure of 17-oxygenated-3-etoxy-6- (a- minometil-disused) pregna-3,5-dien-20-onas. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES359021A1 (en) |
-
1968
- 1968-10-10 ES ES359021A patent/ES359021A1/en not_active Expired
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